c— primary sclerosing cholangitis

Tài liệu Báo cáo khoa học: The diacylglycerol and protein kinase C pathways are not involved in insulin signalling in primary rat hepatocytes doc

... signalling and PKC during hepatic insulin action in a differentiated model for the adult organ, the primary adult rat hepatocyte cultured serum-free with dexamethasone This system shows high insulin ... was included in some experiments Metabolic effects We found that the addition of insulin to our primary rat hepatocyte cultures stimulated glycolysis 4.5-fold, with a 50% effective dose (ED50) ... entirely consistent with our observation that insulin, EGF and TGF-a have no effect on DAG levels in primary rat hepatocytes In contrast, 100 lM ATP and 100 mUÆmL)1 PLC showed a dramatic change in...

Báo cáo khoa học: Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of speciﬁc proteins and functions docx

Danh mục: Báo cáo khoa học

... classes of caveolae, which demonstrate a segregation of functions in caveolae subclasses Results Primary rat adipocytes were homogenized and plasma membranes isolated by differential and density ... analysis membrane in response to insulin stimulation of 3T3-L1 adipocytes, but much less so in primary rat adipocytes [16] We found, however, no signiﬁcant effect of 3386 insulin on the amount ... respectively, in Fig scopy to demonstrate that the localization of the caveolin in the plasma membrane of primary rat adipocytes is found in caveolar structures, with negligible amounts of caveolin in noninvaginated,...

Báo cáo sinh học: " Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages" docx

Danh mục: Hóa học - Dầu khí

... replication (Fig 3) Comparison of the primary isolates of subtype B and subtype C also showed that the subtype C primary isolates replicated better than the subtype B primary isolates These data suggest ... assay in the culture medium (not shown) Replication of subtype C chimeras in primary peripheral blood T-lymphocytes Primary T-lymphocytes from peripheral blood express CD4 and both chemokine receptors, ... HIV-1 subtype C env V3–V5 region chimeras in primary peripheral blood T-lymphocytes (PBL) Replication of HIV-1 subtype C env V3–V5 region chimeras in primary peripheral blood T-lymphocytes (PBL)...

Báo cáo hóa học: " Research Article Opportunistic Spectrum Access in Self-Similar Primary Trafﬁc" docx

Danh mục: Hóa học - Dầu khí

... self-similar primary traffic It builds upon our prior work on a POMDP framework for the joint design of opportunistic spectrum access that adopts a firstorder Markovian model for the primary traffic ... transmission rate Bn (n = 1, , N) These N channels are allocated to a primary network with slotted transmissions The primary traffic in each channel is a self-similar process following the hierarchical ... established, leading to simple, robust, and optimal solutions The first-order Markovian model of the primary traffic, however, has its limitations It cannot capture the long-range dependency exhibited...

Báo cáo y học: "No evidence for an association between the -871 T/C promoter polymorphism in the B-cell-activating factor gene and primary Sjögren''''s syndrome" pptx

Danh mục: Báo cáo khoa học

... 95 patients with pSS The bar represents the standard error BAFF = B-cell-activating factor; pSS, primary Sjögren's syndrome Discussion level in 95 patients with pSS Association between BAFF -871 ... 95 patients with pSS Bars represent mean serum BAFF levels BAFF = B-cell-activating factor; pSS, primary Sjögren's syndrome ± 6.3 ng/ml; P = 0.08) and in the 68 patients with anti-SSA or anti-SSB ... patients with pSS [2-6] Moreover, because one-third of first-degree relatives of patients with primary pSS suffer from other autoimmune diseases [10] and given that BAFF over-expression was also...

Báo cáo y học: "Early Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response" ppt

Danh mục: Báo cáo khoa học

... epithelial cells (SAEC) Cytokine and chemokine secretion by stimulated primary Cytokine and chemokine secretion by stimulated primary small airway epithelial cells (SAEC) SAEC were stimulated for ... µg/ml IgG poly(I:C) Figure Chemokine secretion by stimulated primary small airway epithelial cells (SAEC) Chemokine secretion by stimulated primary small airway epithelial cells (SAEC) (A) SAEC were ... metalloproteinase (MMP) and cells secretion Matrix primary small airway epithelial TIMP (SAEC) by stimMatrix metalloproteinase (MMP) and TIMP secretion by stimulated primary small airway epithelial cells...

báo cáo khoa học: " The effectiveness of behavioural interventions in the primary prevention of Hepatitis C amongst injecting drug users: a randomised controlled trial and lessons learned" pot

Danh mục: Báo cáo khoa học

... enhanced prevention counselling (EPC) in reducing HCV infection in HCV sero-negative patients Our primary hypothesis was that EPC is more effective and cost-effective than simple educational counselling ... months post randomisation, and blood tests for hepatitis C at both six months and twelve months The primary outcome measure was the number of new cases of HCV infection by sero-conversion detected ... otherwise It was also felt that not blinding would have minimal impact on the research outcomes as the primary outcome measure was rate of sero-conversion, which is not open to bias, and in addition...

báo cáo khoa học: " A review of the evidence for the effectiveness of primary prevention interventions for Hepatitis C among injecting drug users" potx

Danh mục: Báo cáo khoa học

... may vary according to data availability [13] However prevalence data is not solely a marker of primary prevention, which is the process of preventing disease transmission It is also a marker ... Therefore, to further understand the epidemiology of HCV so as to explore the effectiveness of primary prevention interventions, the international studies of anti-HCV incidence must be considered ... [20] Either intervention or observational studies were included in the review if they described a primary prevention intervention targeting injecting drug using populations with the outcome to reduce...

Development of direct asymmetric aldol reactions mediated by primary amino acid derived organocatalysts exploring DNA cleaving activities of varacin b and varacin c

Danh mục: Cao đẳng - Đại học

... Scheme 1-12 L-Proline and primary amino acid-mediated enamine catalytic cycles 16 Scheme 1-13 Primary amino acids as organocatalysts for Robinson-type annulation 17 Scheme 1-14 Primary amino acid-promoted ... Subsequently, a number of primary amino acids and their derivatives have been investigated as catalysts for the asymmetric aldol reactions Some selective primary amino acids or peptides with primary amino ... chapter, we describe: (a) catalytic effects of various primary amino acids and their derivatives, (b) the reaction scope of primary amino acid and primary amine-catalysed direct asymmetric aldol reactions,...