... carcinoma - patterns of failure and salvage treatment after curative radiotherapy in 861 consecutive patients Radiotherapy and Oncology 2002, 63:257-267 Yamazaki H, Nishiyama K, Tanaka E, et al: Radiotherapy ... http://www.ro-journal.com/content/6/1/53 Page of Table Univariate and multivariate analysis of factors affecting local control Parameters Events/ patients Uni-variate analysis Table Category- A: grouping according ... univariate and multivariate analysis to determine the hazard ratios and significance of potential risk factors for local control (LC) All statistical tests were two- sided and performed at the...
... backbone carbonyl group of Val4 ofthe peptide andthe backbone amide hydrogen of Ala743 ofthe enzyme, between the side chain carbonyl group of Asn7 of Tat(1–9) andthe side chain of Lys554 of ... differs bythe factor aThe Ki values ofthe inhibition of DP IV by these oligopeptides were in the micromolar range andthea values were in a range between 9.4 and 16 (Table 1) indicating a greater ... ofthe side chain carboxylic group of Glu668 and between the carbonyl carbon atom of Pro ofthe substrate Ala-Pro-pNA andthe Ser630 oxygen atom ofthe enzyme to hold the substrate inside the active...
... containing 100 lm of (GlcNAc)14 was analysed at the start, in the middle and at the end of each series of samples The resulting average values ofthe standards (displaying standard deviations of < 5%) ... regular time intervals The degradation of a- chitin by LlChi1 8A started with a rapid phase, regardless ofthe presence of LlCBP3 3A In the presence of LlCBP3 3A, the fast initial phase was maintained ... instructions, containing ends compatible with the expression vector (forward primer, 5Â-GGTATTGAGGGTCGCCATGGTTATGTTC AATCACCA-3Â; reverse primer, 5Â-AGAGGAGAGTTAG AGCCTTACAAGAAGGGTCCAAAGA-3Â) The PCR product...
... tyrosine kinases participates in growth regulation of human breast carcinoma cells Oncogene 20, 2499–2513 Kanda N, Seno H, Konda Y, Marusawa H, Kanai M, Nakajima T, Kawashima T, Nanakin A, Sawabu T, ... STAT1 The actions of STAT3 and STAT1 are highly entangled, they also have antagonistic activities, and they regulate each others activity Thus, the inhibition of both factors in vivo may have unpredictible ... which was derived fromthe seruminducible element ofthe human c-fos promoter, and RHN(CH2)6- CATTTCCCTTAAATCGAAGATTTAAG GGAAATG-(CH2)3NHR (mutated hairpin control ODN) (Sigma-Proligo; Sigma-Aldrich...
... position ofthe lower jaw to a greater extent than the position ofthe upper jaw in cases of upper and lower jaw surgery Another obvious fact was that male profile with bimaxillary protrusion was not ... and F5 (normal profile) represented Mexican profiles with skeletal Class basal relation and incisor Class with average of cephalometric normal values These were used as templates from which the ... their respective lateral cephalometries were used to generate another manipulated images In these created images, hard tissue normal values were altered in at least two standard deviations Facial...
... Social Research, Zomba, Malawi, James Kaphuka, the National Statistical Office, Zomba, Malawi; and Dixie MaluwaBanda, University of Malawi, Chancellor College, Zomba, Malawi The authors thank their ... health Malawi: Political and Historical Background Malawi is a small landlocked country located in southeast Africa and shares its boundary with Mozambique, Zambia and Tanzania The country was ... (Uganda); Kofi Awusabo-Asare and Akwasi Kumi-Kyereme, University of Cape Coast (Ghana); Alex Ezeh, African Population and Health Research Center (Kenya); and Pav Govindasamy, Albert Themme, Jeanne...
... 174 UCITS types Equity Balanced Total Equity & Balanced Funds of funds (4) Other Total (excl Ireland & Netherlands) of w hich guaranteed funds Total (incl Ireland & Netherlands) 36,733 in No in ... drop was mainly attributable to large outflows from money market funds, as well as concerns regarding the strength ofthe global economic recovery and increasing tensions in the euro area, which ... in net sales of UCITS in April and May following the Japanese earthquake in March was short-lived This can be seen fromthe trends in monthly net sales for UCITS, which shows a sharp turnaround...
... Total Equity & Balanced Funds of funds (4) Other Total (excl Ireland & Netherlands) of w hich guaranteed funds Total (incl Ireland & Netherlands) 35,766 (1 No full data breakdo wn is available ... r EFA M A members fo r which data are available ) EFAMA Quarterly Statistical Release N°50 (Second Quarter of 2012) Trends in the European Investment Fund Industry Net Assets by Country of Domiciliation ... r EFA M A members fo r which data are available; (2) including funds o f funds, except fo r France, Germany and Italy fo r which the funds o f funds data are ) included in the o ther fund catego...
... capacity to dramatically increase the association ofthe p66 and p51 RT subunits [58] Using a yeast two hybrid RT dimerization assay that specifically detects the interaction between the p66 and ... Craigie, R (1991) HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer Cell 67, 1211–1221 62 Asante-Appiah, E & Skalka, A. M (1999) HIV-1 integrase: Structural organization, ... intrinsically asymmetric Thermodynamic evaluations ofthe association between the p66 and p51 subunits of RT have estimated a Gibbs free energyof dimer stabilization of approximately 10–12 kcalÆmol)1,...
... life; as a class, they assemble data about the population as a whole Students examine the data the class assembles and draw a set of important generalizations about cancer from them These generalizations ... its associa tion with the skin cancer on the hand ofa lab technician by 1902 Within a decade, many more physicians and scientists, unaware ofthe dangers of radiation, developed a variety of cancers ... NCI and created the National Cancer Program Over the years, the NCI’s mandate has come to include dis semination of current cancer information and assess ment ofthe incorporation of state -of -the- art...
... right ofthe burning area anda bare tree to the left The Rockies sit in the background, extending about a sixth ofthe way fromthe bottom ofthe frame Parts ofthe sky are the same shade of black ... Ansel Adams I 13 8×10 view camera All of those are heavy, andthe view cameras are extremely hard to handhold and focus because the image is displayed on the back glass upside-down (and you need a ... classes in a tough economic climate Many of these images are portraits of people in daily activities, such as a portrait ofa woman at a crowded beach and one ofa family at the dinner table He also...
... spoken local languages in Ghana The approach adopted for the translation was to first translate the questionnaires into the Ghanaian languages and then back into English The retranslated English ... the past year andthe past three months As was shown in Table 4.2, 30% of females and 16% of males aged 15–19 years and only 1–2% of females and males aged 12–14 years had ever had sexual intercourse ... that 78% of females and 60% of males who had ever had sex reported only one lifetime sexual partner Another 18% of females and 21% of males had two lifetime sexual partners and 4% of females and...
... the steady-state kinetic behavior of wild-type anda subset ofthe mutants of FrdABCD in DW35 membranes The wild-type enzyme has a Km for LPCH2 of approximately 225 lm anda kcat of approximately ... was funded bythe Canadian Institutes of Health Research andthe Canada Foundation for Innovation A. -M.C.S and A. M.S were supported by Alberta Heritage Foundation for Medical Research Summer Studentships ... (at a QD site), and that electron-transfer across the membrane to ⁄ fromthe catalytic dimer is mediated bythetwo hemes in a manner similar to that observed in E coli nitrate reductase A (NarGHI)...
... collected fromthe skin exhibited high antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as against the yeast C albicans As seen in Fig and Table 1, the antiCandida activity ... mm) and for E coli at 2000 and 1000 mm Growth of C albicans was observed at all concentrations of NaCl After incubation ofthe extracts with pepsin, the antibacterial activity ofthe extract was ... activity ofthe cod mucus extract The mucus extract, comprising approximately 42% protein, was assayed for antimicrobial activity against Bacillus megaterium, Escherichia coli and Candida albicans The...
... inhibitor and release of active enzyme A decreased overall inhibition rate can thus be the result ofa shift ofthe rate constants ofthe branched part of mechanism, i.e increased cleavage at the expense ... the thrombin-VR1tPA–PAI-1 interaction appears to Fig TM does not alter the distribution ofthe cleavage and substrate pathway Analysis by SDS/PAGE ofthe products ofthe reaction of 600 nM thrombin ... inactivation ofthe PAI-1 pool in the vascular wall by thrombin, making it no longer available for interaction with u-PA and VN, which can explain part ofthe effect of thrombin on the proliferation and...
... work was supported by grants fromthe Australian National Health and Medical Research Council, the Flinders Medical Centre Foundation andthe Drug and Alcohol Services Council of South Australia ... whereas ATP concentrations fell The extent of these changes andthe rate of glycerol uptake and glucose synthesis were dependent on the initial concentration of added substrate and were maximal by ... for the separation of radiolabelled glucose and its metabolic products, were obtained from Bio-Rad (Hercules, CA, USA) Preparation and incubation of hepatocytes Hepatocytes were prepared from male...
... school levels; staffing and staff development; collaboration between health education staff and other agency and organization staff; andthe educational background and credentials ofthe person who ... 23 state education agencies, and through them their state health agencies, to build state education agency and state health agency partnerships and their capacity to implement and coordinate school ... expectations for health education The Joint Committee on National Health Education Standards released the first set of standards in 1995.15 The National Health Education Standards Review and Revision...
... synergistic actions of ANP and BNP and their cognate receptor GC -A ⁄ NPRA make them novel therapeutic targets in renal, cardiac and vascular diseases The critical physiological and pathophysiological ... cardiovascular sequelae such as hypertension, heart attack, and stroke Nevertheless, the paradigms ofthe molecular basis ofthe functional regulation of Npr1 andthe mechanisms of ANP–NPRA action ... dysplasia [144] Biological actions of GC -A ⁄ NPRA in renal and vascular cells ANP–NPRA signaling in the kidneys promotes the excretion of salt and water, and enhances glomerular filtration rate and...
... Layering and striating all of this early American activity in drafting confederations and constitzrtions kvas the massive brilliance ofthe early American political elite, " u particularly that of Hamilton ... appmaches, and concepts h early exmple of this appmach to the theory of public admkistratian is that af Robert B* Denhardt and Jan Perkirrs (1976), who argued that mainstream organizational analysis ... manage, and have a loud voice in the adjudication ofthe laws within the bomds of his (that is, the sherif-fs)shire That all, ofthe states were influenced by King Edgar % aadministrative creativity...