... structure, the extent to which the substance is absorbed by the body, and the body’s ability to detoxify the substance (change it into less toxic substances) and eliminate it fromthe body The toxicity ... in the type of health effect produced For example, certain organic solvents can cause cancer The way the atoms and molecules cause harm to living tissues is called the mechanism of toxicity The ... laboratory animals If animals were exposed tothe low levels typical of most human exposure, many hundreds of animals would be required for only a few to get cancer To avoid this expense, animal cancer...
... for them! Although the matter of health can be challenging, there are ways to make it easier To start, it is important to learn about the things you can and can’t control Understanding risk factors: ... legs *If you’re an African American, Hispanic, American Indian/Alaska Native, Asian American, or Pacific Islander woman, you’re more than twice as likely as a Caucasian woman to get type diabetes ... family history, cannot be changed But many risk factors can be changed by making simple changes in the way you live Risk factors that you can change (pages 18–25): •Abnormal blood cholesterol and...
... in the N-terminal strand and three in the C-terminal strand This leads to a higher twist of the b sheet of androctonin compared tothe two other peptides Despite such differences, the rmsd of the ... concentration tends to adsorb in the headgroup region of the membrane, leading to a decrease of the thickness of the lipid bilayer, and then to (b) an active state, when the peptide penetrates the hydrocarbon ... similarities between gomesin and peptides belonging tothe families of tachyplesins and polyphemusins from horseshoe crabs [34,35], to androctonin from scorpion [36], and to PG-1 from porcine leukocytes...
... – the cytoskeleton and membrane skeleton – and the specialized arrangement of force-generating components – the contractile apparatus The major components of the cytoskeleton, membrane skeleton ... Wlamin, an actin-associated protein involved in actin polymerization, may be an important regulator of the linkage between the cytoskeleton and the contractile machinery The cytoskeleton also ... returning tothe heart and thus inXuences preload on the heart and hence cardiac output Similarly, the compliance of the aorta and large arteries enables them to accommodate blood ejected from the...
... elements: the Means element (e.g “in a stock-for-stock transaction”) and the Time element (e.g “on October 9, 2006”) Words from these elements, like “stock”, or “October”, are likely to occur ... in positive bags, and vice-versa In order to evaluate the relation extraction performance at the sentence level, we manually annotated all instances fromthe positive test bags The last column ... examples, and they are also many and small – consequently, the two types of bias are not likely to have significant impact on their system’s performance 10 Conclusion References Stuart Andrews, Ioannis...
... draft the manuscript JM, FP and MU participated in the design of the study and helped draft the manuscript KJ conceived of the study, participated in its design and coordination and helped to draft ... progression and poor prognosis in malignant melanoma: An analysis of 215 cases fromthe Malmö Diet and Cancer Study Journal of Translational Medicine 2011 9:114 Submit your next manuscript to BioMed ... significantly improved survival in breast cancer [14] and ovarian cancer [15], and that RBM3 confers cisplatin sensitivity in ovarian cancer cells [15] Apart from these studies, we are not aware of any...
... malignant transformation in the FTE Models of Ovarian Cancer for mechanistic and therapeutic studies Crucial tothe better understanding of EOC etiology and progression, the development and study ... knowledge is translated into clinically effective therapies remains an immediate challenge This meeting has renewed and strengthened the resolve of the Canadian ovarian cancer scientific and clinical ... designed and wrote the manuscript TS synthesized information fromthe meeting, and facilitated in the design and writing of the manuscript All authors read and approved the final manuscript Competing...
... out that more than a half of them not pay attention to small mammals or cannot determine the species and so they are unable to specify which of them contribute tothe damage Among the species classified ... rodents to plantations of forest tree species, to learn about the practical knowledge of foresters related to this problem and to evaluate their positive and negative experiences on the scale of the ... behaviour and the damage they cause At the beginning of the research, we conducted a survey among foresters in the form of a questionnaire with the aim to find out how they perceive the significance...
... attempts to reduce psychiatric hospital bed numbers and provide a stepping stone toward the community, these institutions nevertheless resemble the hospitals that they are supposed to replace Belgian ... for noncompliance with the law are too low to motivate employers” Similarly, occupational doctors, rather than helping on the journey to recovery, are allowed simply to declare an individual ... same remarks on the way to organise the mental health system in Belgium.”2 Nor is anyone in the country under any illusions about the need for change According to Mr Bracke, the more informed...
... to avail themselves of airplanes to find the range for them The French were just at the time trying to get revenge for an attack we made the day before, and the artillery was very busy From there ... also got out to be able to fire at the retreating enemy to better advantage Again and again the French officers tried to close up their ranks, rally their men, and lead them anew tothe attack ... They had been forced to land behind the enemy's line because their motor had stopped They were hardly down when the "Pisangs" (French peasants) came running toward them from every direction They...
... and manage through the daily pushes and pulls of being a manager Chapter 2, Transition: From Individual Contributor to a Manager – One of the most testing times is the transition from being an ... managers must know the situation on the ground, the resolution, and the fact that you managed it well Resource allocator This is another well-understood role A manager is supposed to manage the ... showed me the ropes and put his faith in me when very few would have Thanks to my teams, past and present; to my managers in the past and present; tothe organizations I worked for, and to my teachers...
... means the investigators are willing to take a 5% risk that any differences found were due to chance At the completion of the study, the investigators then calculate the probability (known as the ... pharmaceutical company or other commercial organization funded the study, look for assurances from investigators that this association did not influence the design and results The answers tothe next three ... over another (selection bias) It is important to determine how the investigators actually Is the sample similar to your population? How was the sample selected? The Population The Sample Randomization...
... evaluation The present study therefore adds additional tools tothe analyst's tool-box; increasing the chances that an appropriate tool with be available for the job at hand Findings fromthe present ... edits and revisions tothe manuscript JS contributed tothe acquisition and interpretation of the data, participated in the interpretation of results, and suggested edits and revisions tothe manuscript ... transformations fromthe SF-36 and Barthel tothe AQoL provided sufficient predictive power to suggest that stroke-relevant outcomes can be transformed to preferencebased measures for the purposes...
... over Other than suicide and antidepressant prescribing, the pattern of hospital admissions for depression can be another valid indicator when exploring trends in the prevalence of depression and ... includes data from 2000 to 2005 For every patient discharged froman Italian hospital, an official discharge form (the SDO) needs to be completed and sent tothe Ministry of Health The SDO includes ... in Scotland from 1992 to 2000 Also, the studies by Walsh [14] and Guaiana et al [2], examining admissions in Ireland and in Italy, respectively, referred toan earlier timeframe Our hypothesis...
... would then be reviewed to extract relevant causes in the context of the main presenting problem These causes would then be organized in the ‘fish bones’ of an Ishikawa diagram (Figure 1) There ... students and junior doctors to identify the main presenting problem of a patient, conduct brainstorming sessions and search in the literature to find the potential causes, then categorize these ... this topic Information gathered from other sources can be included in the diagram as well, such as the paper published in the British Journal of Obstetrics and Gynaecology, which has substantiated...
... Instrument of the analysis 2.6.5.1 Constructing the content analysis card To conduct a quantitative content analysis for the textbook I used one tool to collect, describe and analyze data: an analysis ... countries and develop a positive attitude towards the people, cultures and language of these countries; cultivate the pride in, love for and respect tothe Vietnamese culture and language” (Hoang, ... card The criteria to fit into four domains of the analysis card were designed in the light of the criteria for analysis The criteria for analysis were made in the light of the discussion and arguments...
... Differences in the Angle of the Thigh when Embarking fromthe Ground and fromthe Edge of Kerb 103 4.24 The Distance between the Sole of the Left Foot and the Surface of Ground as the Angle of the Thigh ... Rotation Angle, β: Angle between the postural angle plane and the photographic plane; Photographic plane: Plane of the camera on which the image is projected; Optical axis: Line through the optical ... by the Gap Width 27 3.4 One Instance of Describing the Detailed Scenario Settings: The Handrails, the Entrance Step, the Kerb and the Gap between the First Step and the Edge of Kerb 28 3.5 The...
... and appearance Appearance and reality Sense-datum theories and the argument from illusion Other arguments for sense-data Objections to sense-datum theories The adverbial theory of sensation The ... enable the reader to build upon the understanding gained from earlier chapters in getting to grips with the topics of later chapters Rather than include separate guides to further reading for the topics ... activity in the brain, that they would find it more compelling to argue from (2), (3) and the negation of (4) tothe negation of (1) than to argue, as the physicalist does, from (1), (2) and (3) to (4)...