2—design of b regions

Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt

... adhesion inhibition (Eur J Biochem 271) 2877 Fig Ribbon diagram of crystal structure of CD2–CD58 complex and crystal structure of rat CD2 (A) Ribbon diagram of crystal structure of CD2–CD58 (LFA-3) ... hydrogen bonds between NH of Thr5 and CO of Arg2, as well as NH of Arg2 and CO of Thr5 Structure of cyclic hexapeptides – cYT peptide The NMR data of the cYT peptide were indicative of its ﬂexible ... different epitopes to bind to antibody in the antibody binding assay Comparing the concentration of peptides used in inhibition studies by all the three methods, the antibody binding inhibition assay...

Báo cáo khoa học: Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a b-lactamase fold ppt

Danh mục: Báo cáo khoa học

... a 1.4 kb EcoRI ⁄ HindIII fragment containing the Hyb-24gene [4,7] [7–9] Hyb-24 Hyb-24D Hyb-24D-A112 Hyb-24N Hyb-24Y Hyb-24DN Hyb-24DN-A112 Hyb-24DY Hyb-24DNY Hyb-24DNY-A112 Hyb-24DD Hyb-24DG ... available: Fig S1 Stereoview of the catalytic cleft of Hyb-24DN Fig S2 Stereoviews of surface structure of Ald-bound and unbound Hyb-24DNY Fig S3 Stereoview of the catalytic cleft of Hyb24DNY ... substitution decreased the Km to mm (23% of the level of Hyb-24D), but barely affected the kcat value (see Hyb-24DY) Thus, D370Y substitutions mainly improved Ald binding In Hyb-24DN, D370Y substitution...

Báo cáo khóa học: Conformational changes of b-lactoglobulin in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles A ﬂuorescence and CD study docx

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... Ó FEBS 2004 Conformational changes of bLG in reverse micelles (Eur J Biochem 271) 735 Scheme Ribbon diagram of a single unit of bovine b- lactoglobulin (bLG) drawn using SWISS PDBVIEWER, ... may be induced by high temperature as well as by encapsulation in AOT RM A decreased ratio of native dimers to monomers, and the loss of H-bonding involving the strands bI of bLG [47], could be ... that of bovine bLG As mentioned previously, disulﬁde bonds also contribute to the near-UV CD spectrum, giving a broad band near 260 nm that seems to be related to the dihedral angle of the bond...

Báo cáo khoa học: Identiﬁcation and characterization of B¢¢-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues Evidence for an independent N-terminal splice variant of PR130 and an extended human PR48 protein pot

Danh mục: Báo cáo khoa học

... Sozzi, G., Croce, C.M., Barbanti-Brodano, G., Russo, G & Negrini, M (2000) Low frequency of alterations of the a (PPP2R1A-) and b (PPP2R 1B) isoforms of the subunit A of the serine-threonine phosphatase ... part of PR130 which has the highest similarity with other subunits of the B ¢-family and has been demonstrated to contain two putative A-subunit binding domains responsible for PR65/A-subunit binding ... homology (accession number AL555389 being the longest) Figure 3B shows an alignment of the ﬁrst 340 bp of cDNA sequences of human PR48 (accession number: AF135016), the ﬁrst 868 bp of Xenopus PR70 and...

Báo cáo khoa học: Side-chain control of b-peptide secondary structures Design principles doc

Danh mục: Báo cáo khoa học

... interactions stemming from b2 or b3 substitution cannot bring about a prevailing h in solution, but by means of b2 ,3 disubstitution the conformational preference along the C2-C3 bond can be modulated successfully ... structures possess helical symmetry, but strands will be distinguished from helices on the basis of the angle of the backbone H-bonds The structures stabilized by H-bonds with an angle < 120° are classiﬁed ... Fulop (Eur J Biochem 270) ¨ ¨ Ó FEBS 2003 Fig General constitution, deﬁnition of the backbone torsions and designation of the substitution pattern of b- amino acid residues body of high-resolution...

Báo cáo hóa học: " Design of Uniformly Most Powerful Alphabets for HDF 2-Way Relaying Employing Non-Linear Frequency Modulations" ppt

Danh mục: Hóa học - Dầu khí

... Defining a symbol error ∂ AB ≠ c AB , the symbol error probability is well approximated by sum of weighted pairwise error probabilities The pairwise error probability is a function of distance between ... ||scB − scB ||2 − 2|α| scA − scA , scB − scB ≥ |α|2 δmin , Page 16 of 18 for c A ≠ c A ’, c B ≠ c B ’, c A ⊕ c B ≠ c A ’ ⊕ c B ’, where cA , cB , cA , cB , ∈ ZMc and ∀a Î ℂ, |a| ≤ Assume a biorthonormal ... perform Viterbi decoding (31) where auxiliary constants b = scA − scA , scB − scB 2 || scB − scB || − δmin , b ≥ (32) and c = b2 + ||scA − scA ||2 ||scB − scB ||2 − δmin are not functions of |a| Thus,...

Báo cáo hóa học: " Transformation of b-Ni(OH)2 to NiO nano-sheets via surface nanocrystalline zirconia coating: Shape and size retention" potx

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... Fig 2 (b3 ) First, pure cubic NiO phase was revealed and monoclinic ZrO2 was not observed It was possible that the amount of the ZrO2 was much less compared to that of NiO The broadening of the ... surface Fig Schematic illustration of synthesis of ZrO2-coated NiO nano-sheet 123 30 Fig XRD patterns of (a) the synthesized b- Ni(OH)2, (b1 ) 300NiO, (b2 ) 600-NiO, and (b3 ) 600 °C-treated ZrO2-coated ... retarded by the surface ZrO2 The fact of the nano-sized nature of the ZrO2coated NiO could also be evidenced by nitrogen absorption measurement For the 600 °C-treated ZrO2-coated NiO, the BET surface...

Báo cáo hóa học: " Research Article Noniterative Design of 2-Channel FIR Orthogonal Filters" pptx

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... Again, by using (27), the sum of the coefficients of h is a linear combination of the sum of each one of the two columns: s = h1 + ut (b + c) + hL + ut (c − b) (34) so we get the equation of a straight ... part of the complex number We summarize that the coefficients of P, which are the autocorrelation coefficients r(n) of the filter, can be easily obtained by means of the coefficients of C and B2 (resp., ... Pheven = c −Pb h1 hL hL −h1 + At b = − bt a ≥ 1, = bt I + AAt b = −bt a ≥ 1= h (26) ⎞ (29) (28) (30) Due to the orthogonality of the two columns of this expression (27), the norm of h is very...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 1 Part 2 doc

Danh mục: Kĩ thuật Viễn thông

... of the tube by a conduction process which is controlled by the tubewall's thermal conductivity and tube-wall thickness The transfer of heat from the outside wall of the tube to the bulk of the ... Btu/hr-ft2-°F k = bath fluid thermal conductivity, Btu/hr-ft-°F C = bath fluid specific heat, Btu/lb-°F p = bath fluid density, lb/ft3 P = bath fluid coefficient of thermal expansion, 1/°F [i = bath fluid ... be added or removed from the process fluids to create the required change in temperature This can be in the form of sensible heat, latent heat, or both Sensible Heat The amount of heat absorbed...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 1 docx

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... countercurrent to the absorber oil The gas leaves the top of the absorber while the absorber oil, now rich in light hydrocarbons from the gas, leaves the bottom of the absorber The cooler the inlet ... amount of reboiler duty, the composition of the bottoms liquid can be determined By decreasing the pressure and increasing the bottoms temperature more methane and ethane can be boiled off the bottoms ... MMcf x 90 Ib/MMcf = 1,500 Ib H2O/cycle Loading Because of the relative cost, use Sorbeads as the desiccant and design on the basis of 6% loading Sorbeads weigh approximately 49 lb/ft3 (bulk density)...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 2 pps

Danh mục: Kĩ thuật Viễn thông

... approximation of the number of stages can be made by assuming a maximum compressor ratio per stage of 3,0 to 4.0 and choosing the number of stages such that: where R = ratio per stage n = number of stages ... must be known The detailed calculation of horsepower and number of stages depends upon the choice of type of compressor, and the type of compressor depends in part upon horsepower and number of ... number of stages has not been selected or additional cooling of the suction gas is required If the suction gas temperature to each stage cannot be decreased, increase the number of stages by...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 3 potx

Danh mục: Kĩ thuật Viễn thông

... rod by the pressure differential between the two ends of the piston Each frame is designed for a maximum number of cylinders The frame itself does not indicate the number of stages or the duty of ... compressor cylinders may be reduced by 25% by unloading the outer end of one cylinder and by another 25% by unloading the outer end of the second cylinder Unloading the frame ends of the cylinders at ... clearance is important, because it allows variable clearances (both fixed volume and adjustable volume pockets) to be used to control capacity and obtain the maximum use of available driver horsepower...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 4 pdf

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... sizing rules of thumb discussed above, in conjunction with pulsation bottles sized from Figure 11 -24, should be sufficient for individual field compressors These rules of thumb can also be used for ... moments tha cannot be completely eliminated and must be absorbed by the foundation The manufacturer has the ability to rninimize the magnitude of these forces and moments by adding counterweights ... classes Table 12-2 is a summary of the more detailed Table 9-11 in Volume (1st Edition: Table 99) and presents the MAWP of carbon steel fittings manufactured in Table 12-1 Setting Maximum Allowable...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 5 pps

Danh mục: Kĩ thuật Viễn thông

... Scrubber Heat Exchanger Compressor Scrubber Compressor Discharge Blocked Discharge Blocked Discharge Blocked Discharge or Blowby Fire Gas Blowby or Fire Regulator Failure Tube Rupture Fire Blocked ... from both sides of the break A vessel may be subject to more than one condition under different failure scenarios For example, a low pressure separator may be subject to blocked discharge, gas blowby ... could be damaged when the relief Mechanical Design of Pressure Vessels 349 VENT HOLES In service of hydrocarbons or other combustible liquids or gases the skirts shall be provided with minimum of...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 6 docx

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... pilot-operated and balanced-bellows relief valves, the capacity is reduced as the back-pressure goes above a certain limit Pressure Relief 369 For balanced-bellows relief valves, above about 35% back-pressure, ... For subcriticat flow back-pressures below 50 pounds per square inch gauge, the manufacturer must be consulted for values of /Cb Figure 13-8 Bock-pressure sizing factor, Kk, for balanced-bellows ... disc This is called "backflow protection." A backflow preventer should be specified if the vessel could be subject to vacuum, such as a compressor suction scrubber, or where the back-pressure in...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 7 docx

Danh mục: Kĩ thuật Viễn thông

... Fire tubes can also be a source of ignition if the burner controls fail and the tube overheats or if the pilot is out and the burner turns on when there is a combustible mixture in the tubes Because ... independent back-up to the sensor as a second level of defense before an identified hazard is created The degree of reliability of the back-up device will be dependent upon the severity of the problem ... probability of building failure should be lower than the probability of tripping because of the severity of injury that may be associated with building failure Figure 14-1 Hazard tree for injury suffered...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 8 docx

Danh mục: Kĩ thuật Viễn thông

... (Ambient Temperature) N Pressure Vessel (Heated) P Q Z Pump Wellhead Other BG AR, AS, AT AA, AH, AQ AG AB, AD, AF, AJ, AK, AM, AV, BD, BF, BH, BJ, BL, BM AC, AF, AM,AP BC, BD, BG, BJ, BK AX, BA, ... BM AC, AF, AM,AP BC, BD, BG, BJ, BK AX, BA, BE AR, AT, AY, AZ AL AM AN AP AQ AR AS AT AU AV AW AX AY AZ A1-A9 BA BB BC BD BE BF BG BH BJ BK BL BM BN ZZ Forced Draft Free water Knockout Generator ... Hydrocarbons Corrosive Hydrocarbons Corrosive Hydrocarbons Corrosive Hydrocarbons Corrosive Hydrocarbons Corrosive Hydrocarbons Corrosive Hydrocarbons General ISOlbANSI 300 Ib ANSI 400 Ib ANSI 600 Ib...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 9 ppt

Danh mục: Kĩ thuật Viễn thông

... such as Table 15-2, or from a separate valve specification for VBF-15-1, as shown in Table 15-5 Table 15-3 Comparison of Valve Properties Valve Bubble Tight Ball Yes Plug Yes Gate Yes Butterfly ... should be socket welded for: Hydrocarbon service above 600 ANSI Hydrocarbon service above 200°F Hydrocarbon service subject to vibration Glycol service • Pipe inches and larger should be flanged ... facility piping is fabricated from ASTM A-106 Grade B or API 5L Grade B pipe, which is acceptable for sweet service and temperatures above ~20°F Between -20 °F and -50 °F, ANSI B3 1.3, "Chemical Plant...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 10 pptx

Danh mục: Kĩ thuật Viễn thông

... will be throttled through the valve manually during the bypass operation, or it could be an on/off valve if the flow is to be cycled Because globe valves not provide positive shutoff, often globe-bypass ... reasonable distance upstream and downstream so that the choke bean or disc can be changed without having to bleed down a long length of pipeline A vent valve for bleeding pressure off the segment of ... separation is not often done because of the expense of separating two chokes by a spool of pipe rated for well shut-in pressure It is much less expensive to bolt the flanges of the two chokes...

ARNOLD, K. (1999). Design of Gas-Handling Systems and Facilities (2nd ed.) Episode 2 Part 11 ppsx

Danh mục: Kĩ thuật Viễn thông

... cable, the facility could be shut in for extended periods of time To avoid extended shut-ins, either a spare or alternate cable can be installed or standby generators can be installed on the offshore ... may be present—gas, dust, or fiber; second, one must designate the specific "group" of the hazardous substance; third, one must determine the probability that the hazardous substance will be present ... characterize substances by Groups designated as I, IIA, IIB, and IIC Group I is applicable to below-ground installations where methane may be present Group IIA is applicable to above-ground installations...

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