1920— member of the tuscan branch of the house of habsburg lorraine
Tài liệu Báo cáo khoa học: Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family pptx
... to the residue in the midpoint of the respective loop, as shown in Fig To the east of the active site the 37- and 60-loops border the S2¢ pocket of the proteinase The observed differences in the ... below) The southern boundary of the active site cleft of DESC1 is formed by the 145 autolysis loop The backbone of this loop differs markedly from the other serine proteinases, making the active ... that the most similar regions of these proteinases mediate interaction of the two b-barrels, formation of the catalytic machinery and structures required for binding of the main chain of the substrate...
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Báo cáo khoa học: Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily pot
... 1B) The partial phosphorylation of Grx4p still observed in the case of the two mutants (corresponding to 30–40% of that of the wild-type) could be explained either by the intervention of another ... in the phosphorylation of Bud32p at Ser258 In order to investigate the impact of Ser258 substitution in vivo, we compared the growth of the S258A mutant with that of the wild-type strain and of ... elongation We have then examined the effects of Ser258 phosphorylation of Bud32p on the transcriptional activity of the EKC ⁄ KEOPS complex by analyzing the activation rate of the galactoseinducible...
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Báo cáo khoa học: Identification and characterization of a nuclear receptor subfamily I member in the Platyhelminth Schistosoma mansoni (SmNR1) pot
... vitro DNA binding of a protein containing 20 amino acids at the 5¢ end of the DBD, the DBD and the 40 amino acids at the 3¢ end of the DBD of SmNR1 (Ile247-Ser372) and SmRXR1 (Glu251-Asn376) were ... acids The role of the large hinge in schistosome NRs remains unknown The degree of conservation of the LBD in SmNR1 is lower, helices 1–2 are highly divergent as mentioned above, like that in other ... Although the LBD of SmNR1 is less conserved, the consensus signature of LBD (F,WY)(A,SI)(K,R,E,G) XXX(F,L)XX(L,V,IXXX(D,S) (Q,K)XX(L,V)(L,I,F) [15,16] (from the C-terminus of helix to the middle of...
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Báo cáo khoa học: Epl1, the major secreted protein of Hypocrea atroviridis on glucose, is a member of a strongly conserved protein family comprising plant defense response elicitors potx
... the members of the cerato-platanin family as the best hits It is possible that they represent an ancestral cerato-platanin member that is no longer present in the other genera Transcription of ... strands, and the black line indicates coiled, unstructured regions The bars at the location of the corresponding amino acids indicate the confidence of the secondary structure prediction The vertical ... agent of the human respiratory disease San Joaquin Valley fever, was proposed as a Coccidioidesspecific antigen for the diagnosis of this fungus [30,31] The restricted description of members of the...
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Báo cáo khoa học: O-MACS, a novel member of the medium-chain acyl-CoA synthetase family, specifically expressed in the olfactory epithelium in a zone-specific manner doc
... acetyl-CoA synthetase (AceCS) family was much less (20–30%) These observations indicate that the O-MACS protein is a novel member of the acyl-CoA synthetase family, belonging to the subtree of the MACS ... They are linked in tandem to the 7F1 region of the mouse chromosome The o-macs gene is composed of 14 exons including 12 coding exons (D) Tentative linkage map of the human MACS gene family The ... layers of the OE (Fig 2A), although the level of expression in the OSN layer is somewhat lower than those in other cell-layers The o-macs transcripts were also detected in the cells within the lamina...
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Báo cáo Y học: Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases pdf
... parasites of the genus Giardia are one of the earliest lineages of eukaryotic cells, and the Giardia protease is the earliest known branch of the cathepsin B family [23] Its phylogeny confirms that the ... concentrating the allergen according to the isoelectric point (pI) of the molecule A pH gradient from to 11 was established for the characterization of Phl p After completion of the run, the individual ... further explore the biochemical function of group I allergens Expression of glycosylated and nonglycosylated rPhl p reveals differing stability of these allergens The expression of rPhl p in the...
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Báo cáo khóa học: Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus A member of a novel protein family related to protein disulfide-isomerase doc
... the presence of the nucleotide These experiments indicate that the binding and/or hydrolysis of ATP not have any effect on the conformation of PfPDO, possibly because of the localization of the ... participation of both N-terminal and C-terminal active sites Refolding of the scrambled RNase in the presence of PDI was used as a positive control, and the absence of the recovery of the RNase activity ... using PDI However, the temperature of the assay, which is limited by the stability of the protein substrate RNase, is very far from the optimal growth temperature of the hyperthermopilic micro-organism...
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Báo cáo khoa học: Characterization of ubiquitin-like polypeptide acceptor protein, a novel pro-apoptotic member of the Bcl2 family pptx
... performed immunoblotting of the 33.5 kDa Ubi-L adduct using an antibody against synthetic peptide based on the sequence of Bcl-G The results of the Fig Primary structure of Bcl-G (A) The predicted amino ... the gene products of Bcl-G and Ubi-L The fourth column indicates the number of the first and last amino acid of the identified Bcl-G and Ubi-L peptides, whereas the fifth shows the corresponding ... bonds between the C terminal of the glycine residue of Ubi-L and the lysine of Bcl-G The 33.5 kDa Ubi-L adduct was digested by V8 protease and subjected to MALDI-MS analysis The data in the first column...
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Báo cáo khoa học: The proapoptotic member of the Bcl-2 family Bcl-2 / E1B-19K-interacting protein 3 is a mediator of caspase-independent neuronal death in excitotoxicity pot
... excitotoxicity BNIP3 is a BH3-only proapoptotic member of the Bcl-2 family However, unlike in other members of the Bcl-2 family, the BH3 domain of BNIP3 is not required for its death-inducing ... striatal areas adjacent to the site of injection (Fig 1A) High levels of BNIP3 immunostaining were found in the cytoplasm of striatal neurons affected by the KA, and almost all of the BNIP3positive neurons ... agonist for the kainate receptor (a subtype of the ionotrophic glutamate receptor) that mimics the effect of glutamate Of the 15 rats that received KA injections, five were used for preparation of brain...
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Báo cáo khoa học: Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily ppt
... for other members of the superfamily Results Conservation of L6 sequence in the superfamily The VRGY motif is located at the tip of L6 of FhaC, which reaches the periplasm Alignments of the FEBS ... subtypes of TPS system have been identified, which differ by the sequences of the TPS domains of the TpsA proteins and by those of their TpsB transporters [16,18] Nevertheless, the structure of the ... 1) Furthermore, the analysis of the sequences of a large number of predicted Toc75, Sam50 and Omp85 homologues indicated the presence of a closely related tetrad in the vast majority of these...
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THE WESTMINSTER KENNEL CLUB (Member of the American Kennel Club) JUDGING PROGRAM 2013 pptx
... ready to bring into the judging ring promptly The owner of the dog or the handler is responsible for the presence of their dog in the judging ring There is no rule of this Club or the American Kennel ... at the show is in the care and custody and control of its owner or handler during the time the dog is on the show premises See also the agreement on the reverse of the entry form The welfare of ... show, the grounds, site and show areas for whatever purpose so entirely at their own risk By virtue of entering the show, the entrant has indicated their acceptance of the terms listed in the premium...
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Báo cáo khoa học: Identification of a copper-repressible C-type heme protein of Methylococcus capsulatus (Bath) A member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins docx
... located in the core of the CCP structure (Fig 3A) Furthermore, all of the additional insertions of the extended MCA2590 sequence are introduced in loop regions on the surface of the structure, thereby ... Detection of C-type heme Because of the sequence similarity of SACCP to members of the BCCP family of proteins and the prediction of heme-binding motifs in the primary sequence, it was of interest ... located on the cellular surface of the bacterium Furthermore, expression of MCA2590 also responded to the availability of copper, and was abundant when copper was scarce in the growth medium The MCA2590...
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Báo cáo Y học: A functionally conserved member of the FTZ-F1 nuclear receptor family from Schistosoma mansoni doc
... to the alternative splicing of the two 5¢ exons of the gene (see below) The 3¢ end of the sequence is not supported by the presence of a classical consensus polyadenylation signal upstream of the ... from the platyhelminth human parasite, Schistosoma mansoni [22] We are now studying the properties of these receptors to determine the level of conservation of their function and their role in the ... and E domains to members of the FTZ-F1 nuclear receptor family (A) Domain structure of SmFTZ-F1 and levels of identity of the peptide sequences of the C and E domains to those of C elegans nhr25...
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Báo cáo khoa học: Extrinsic proteins of photosystem II An intermediate member of the PsbQ protein family in red algal PS II ppt
... from the thermophilic cyanobacteria as long as the 33-kDa protein is present On the other hand, the full binding and functioning of the 12-kDa protein and cyt c-550 requires the presence of the ... indicates that the gene is located in the nuclear genome of the red alga, consistent with the fact that homologous sequence of the gene was not found in the plastid genome of two species of red algae, ... from the 5¢- and 3¢-RACE, respectively Sequencing of these cDNA fragments confirmed that they contained the cDNA for the 20-kDa protein These sequences were combined with the partial sequence of the...
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Báo cáo Y học: Characterization of a Saccharomyces cerevisiae NADP(H)-dependent alcohol dehydrogenase (ADHVII), a member of the cinnamyl alcohol dehydrogenase family pptx
... was obtained with the CLUSTALW program Thin arrows mark the aminoacids involved in the binding of the Ôcatalytic zincÕ The thick arrows point the Cys involved in the binding of the Ôstructural ... this case, with the purpose of regenerating NADP The manipulation of the levels of ADHVI and ADHVII could be used by the fermentation industry to alter the organoleptic properties of the fermented ... coenzyme, the reduction with NADH is 7% of that found for NADPH, in the presence of mM cinnamaldehyde, while the activity found with NAD was 20% of the NADP-dependent activity in the presence of mM...
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Báo cáo hóa học: " The genome and proteome of the Kluyvera bacteriophage Kvp1 – another member of the T7-like Autographivirinae" docx
... profile (Fig 3) in which most of the protein bands can be assigned based upon the extensive knowledge of these phages, and the mass of the protein bands compared with the in silico analysis of ... Underneath the name (Kluyvera phage Kvp1) is ruler in kb, the degree of sequence similarity, indicated by the intensity of the red region, and, the gene map with the position of genes indicated Page of ... (Lane A) The masses of the proteins are indicated in the adjacent lanes The tentative identification based on in silico analysis of the properties of the gene products (Gp) are indicated on the right...
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roadshow mexico city on 7 8 may 2014 thomas aebischer holcim group cfo and member of the executive committee urs birri cfo holcim mexico thomas rueger treasury relationship manager angel garcía de quevedo treasure
... has been a subsidiary of Holcim since 1964 • In 2004, Holcim Group acquired 31% of the remaining shares of Holcim México, becoming the sole shareholder • In 2013, the name of the company changed ... CAPEX net w ill come from prioritization of CAPEX based on the speed of the returns (ROIC) Current energy fund of CHF 100 million w ill be maintained through the period 2012 - 2014 3) Original amount ... to achieve the savings (one-off) Additional CAPEX net 2) 239 48 3) 100-180 1) The base line is the financial year 2011 amounting to CHF 2,308 million (excluding one-off charges 2011 of CHF 375...
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holcim in latin america andreas leu member of the executive committee 2012 holicim ltd
... because they trusted me and gave me the opportunities, which allowed me to grow personally and professionally thereby supporting me all the way ” Plant Manager of Holcim Argentina • “During the 19 ... Commercial Director of Holcim Argentina • “Besides the enriching personal and professional experience within the Group, the opportunities offered by Holcim rewarded me with a number of external acknowledgments” ... acknowledgments” General Director of Holcim Nicaragua, “Entrepreneur Woman of the Year for the Construction Industry” and “Extraordinary Services Provider to the Central America Construction Industry”,...
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holcim in south asia asean paul hugentobler member of the executive committee 2012 holcim ltd
... Singapore • The Centre of Excellence (CoE) was built with the support from the Singapore Economic Development Board (EDB) • Aligned with Government of Singapore economic development priorities • The ... commissioning of first line in Tuban (East Java) end of 2013 • Catch up with fast growing Java and the Islands through second line in Tuban • Expand asset footprint in Southern Sumatra to further optimize ... Continuous population growth of around 2% per annum on a current base of more than 1.2 billion raises sustainability issues • Millions of young people aspire to be integrated into the workforce • Inflation...
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Báo cáo y học: "Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis" ppt
... preparation of the manuscript SL performed some of the cell experiments DB performed ELISA assays, bioassays, and some of the transfection experiments AT contributed to the conception of the study and the ... For the simultaneous comparison of the survivin levels in more than two groups the equality of variance F test was employed The inter-relation between the survivin levels and duration of the ... of survivin, departing from the level of survivin that corresponded to a mean + three standard deviations of the control group as a cut-off The difference in the mean survivin level between the...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu