... implicated in FasL expression [17] This possibility is supported by our preliminary experiments showing that H2O2-induced FasL expression in endothelial cells is enhanced by vanadate, a protein tyrosine ... ischemia/reperfusion injury, hyperoxia, and radiation injury Previous studies have shown that increased oxidative stress induces FasL expression by T-lymphocytes [8], microglial cells [9], and intestinal epithelial ... [19] In this context, the oxidative stress- induced increase in endothelial soluble FasL production observed in this study may contribute to maintaining homeostasis of the systemic vasculature Oxidative...