Association studies of genetic polymorphisms found in interleukins 12, 13 and CD14 gene with asthma and allergic diseases
Association studies of genetic polymorphisms found in interleukins 12, 13 and CD14 gene with asthma and allergic diseases
... Introduction The morbidity and incidences of allergic asthma particularly in children are increasing worldwide The role of interleukin -13 (IL -13) as one of the major players in the genetics of ... Function and Role of Interleukin 13 (IL -13) The human interleukin -13 gene (IL -13) exists as a single copy in the haploid genome, and it maps to chromosome [51] Interleukin 13 levels have been found ... cytokine genes (interleukins 3, 4, 5, 9, 13 and the β-chain of the IL-12 gene) , CD14 gene and genes coding for the corticosteroid receptor and the granulocyte macrophage colony stimulating factor...
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GENOME WIDE ASSOCIATION STUDIES OF CORONARY ARTERY DISEASE IN SINGAPOREAN CHINESE POPULATIONS
... Singapore Coronary Artery Genetics Study xv SCES: Singapore Chinese Eye Study SCES: Singapore Chinese Eye Study SCHS: Singapore Chinese Health Study SiMES: Singapore Malay Eye Study SINDI: Singapore ... that studies of coronary artery disease in Asia are conducted to address this increasing burden 1.3 Overview of the etiology of coronary artery disease The etiology of CAD is multifactorial, involving ... findings 2.3.1 GWAS of CAD Genome wide association studies have identified multiple genetic variants associated with CAD Most of the associations have been replicated in independent studies, indicating...
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Báo cáo y học: "Role of Genetic Polymorphisms in Therapeutic Response to Anti-Asthma Therapy" pot
... the very exciting literature regarding potential phenotypic and genotypic indicators of response to therapy because one or the combination of both of these tools will likely be a clue to a patient’s ... we may be able to rely on a patient’s genetics to aid in choosing the most appropriate therapy As clinicians attempting to stay current in the evolving science of asthma, we must continue to follow ... Oppenheimer, Role of Genetic Polymorphisms in Therapeutic Response to Anti-Asthma Therapy homozygous for Arg-16 who had regularly used albuterol had a morning peak expiratory flow of 30.5 12.1 L/min lower...
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Association analysis of genetic variation of estrogen related candidate genes in breast and endometrial cancers
... DEPARTMENT OF EPIDEMIOLOGY AND PUBLIC HEALTH YONG LOO LIN SCHOOL OF MEDICINE NATIONAL UNVERISTIY OF SINGAPORE Association Analysis of Genetic Variation of Estrogen Related Candidate Genes in Breast and ... further explore the association between genetic variants in ESR2 and breast cancer risk 7.5 Candidate gene based genetic association study Candidate genes are chosen in genetic association studies ... explore the association between genetic variants in ER cofactor and breast and endometrial cancer 7.5.3 Estrogen metabolism enzymes and ER cofactor genes are drug targets for breast and endometrial...
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Association study of ABCA1 polymorphisms in singapore populations 6
... allele was present at frequencies of 65 % in both Chinese and Indians, and 68 % 129 Chapter Association Study of ABCA1 Polymorphisms in Singapore Populations in Malays, with no significant differences ... Chapter Association Study of ABCA1 Polymorphisms in Singapore Populations 6. 2.2.2 237indelG 237indelG is a one-base insertion/deletion (indel) polymorphism of a G nucleotide found within the untranslated ... Chinese and Malay populations showed no evidence of an association with CAD at the 237indelG locus (Table 6. 5) 132 Chapter Association Study of ABCA1 Polymorphisms in Singapore Populations 6. 2.2.3...
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Association study of ABCA1 polymorphisms in singapore populations 5
... AJ012376 NM 0 055 02 AF1 652 81 AF2 851 67 EST AI802228 AA627178 AI80 753 4 AI 356 194 AI628099 R01 050 R01 051 AA527406 AI 359 714 AA9029 25 AA493786 AI399824 AA731742 AI819 656 R31961 AW 051 752 AA814091 AI6 950 68 AA883989 ... denaturing conditions Primers were designed to amplify most of the 50 exons individually including the entire 5 UTR and the protein coding portion of exon 50 In addition, a fragment containing ... Type 5' UTR 2C>T Intronic IVS1+92T>C Intronic IVS3+44C>G Intronic IVS2+123C>T 5' UTR 296C>G 5' UTR 237indelG Intronic IVS3+35C>T Intronic IVS2-33A>T Intronic IVS2-42C>T Intronic IVS2 -51 A>G Intronic...
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Association study of ABCA1 polymorphisms in singapore populations 4
... aligned using ClustalW 44 Chapter Materials and Methods -515 -49 4U PrU -564T>C -41 7 -40 0U -46 3C>T TSS +1 -40 7G>C -302C>T -278C>G -99G>C -14C>T +280+297L PrL Primers PrU -515 49 4U -41 7 40 0U PrL +280-+297L ... 63 o 56 C 342 107 o 55 C 3 64 142 o 55 C 311 135 o 59 C 333 1 04 o 57 C 44 8 93 o 56 C 43 6 245 o 59 C 41 3 141 52, o 57 C 48 Chapter Materials and Methods 4. 3 Genetic Association Study 4. 3.1 Cases ... 5’-TTCCTGCTATCTCCCACTACCA-3’ 5 14 221 o 60 C 510 136 56oC 382 66 60oC 47 0 94 406 142 54, 59oC o 58 C 40 6 119 o 61 C 46 3 122 538 177 54, 59oC o 57 C 48 5 93 526 241 53, 58oC o 59 C 3 54 140 60oC 347 117 60oC 333...
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Association study of ABCA1 polymorphisms in singapore populations 3
... gene-environment interactions are investigated, even larger sample sizes are probably necessary (Ioannidis, 20 03) 3. 6 .3 Chance Findings In a typical association study, each SNP is tested for association in ... required before selecting suitable SNPs for an association study 3. 6.6 Confounding One main drawback of the association study is its potential for confounding arising from correlation of other factors ... Traits 3. 5.2 Whole Genome Association Studies The genome scan approach involves genotyping of a dense map of SNPs arrayed across both coding and noncoding regions in cases and controls (Collins...
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Association study of ABCA1 polymorphisms in singapore populations 2
... that ABCA1 over-expression raises HDL-C (Vaisman et al., 20 01; Singaraja et al., 20 01) Joyce et al (20 02) provided first proof of a direct anti-atherogenic role for ABCA1: expression of human ABCA1 ... phosphatidylethanolamine (Rye et al., 1999) 2. 2 .2 Laboratory Determination of HDL In routine biochemical analysis, HDL in plasma is assayed as the total cholesterol content (free cholesterol and CE) following ... that include increased lipoprotein lipase (LPL)-mediated lipolysis leading to lower TG, and transcriptional induction of ApoAI and ApoAII culminating in higher HDL (Staels et al., 1998) These clinical...
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Association study of ABCA1 polymorphisms in singapore populations 1
... normolipidemic Inuits The two major objectives of the dissertation were: Identification of ABCA1 polymorphisms that might be useful in a genetic association study; and Association analysis of ABCA1 SNPs ... contribution of ABCA1 SNPs to inter-individual differences in CAD susceptibility and intermediate phenotype variation, with only Wang et al (2000) reporting an association of M883I with HDL-C levels in ... levels in Singapore Chinese, Malays and Indians For the SNP discovery phase, we combined in silico and experimental approaches DHPLC was the method of choice for a quick scan of the coding region of...
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Tài liệu A REVIEW OF INDOOR AIR POLLUTION AND HEALTH PROBLEMS FROM THE VIEWPOINT OF ENVIRONMENTAL HYGIENE: FOCUSING ON THE STUDIES OF INDOOR AIR ENVIRONMENT IN JAPAN COMPARED TO THOSE OF FOREIGN COUNTRIES pptx
... to total concentrations of multiple indoor air pollutants It is used as a complementary indicator to decrease indoor pollution level in total and achieve healthy indoor air environment. 109) The ... determination and the comparison of their value Indoor Environ., 11, 1–9 (in Japanese) Fukutomi, Y., Yasuda, H., Nakazawa, T., Taniguchi, M and Akiyama, K (2009) Indoor Mite and Insect Allergens and ... E., Ohno, H and Nakajima, T (2009) Annual transition and seasonal variation of indoor air pollution levels of 2-ethyl-1hexanol in large-scale buildings in Nagoya, Japan J Environ Monit., 11, 2068–2076...
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A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians doc
... monozygous twins, full siblings, and parent-offspring In each instance, the sample with the higher call-rate was retained in the analysis Analysis of association statistics After sample and SNP quality ... Working Group, Medical Faculty, University of Indonesia, Jakarta, Indonesia 8Samara Oblast Tuberculosis Dispensary, Samara City, Samara, Russian Federation 9Clinical TB and HIV Group and Health ... and sampling sample in Russia SN participated in sample collection in Russia and association analysis of the Russian data Competing interests The authors declare that they have no competing interests...
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zen ritual studies of zen buddhist theory in practice nov 2007
... of Zen Buddhism This page intentionally left blank Zen Ritual This page intentionally left blank Introduction: Rethinking Ritual Practice in Zen Buddhism Dale S Wright Role of Ritual in Zen ... Describing the ritual as it is performed today in Japan, the essay shows how continuity of ritual tradition is maintained in Zen even into the postwar era in which the Emperor’s role in maintaining ... permission of Oxford University Press Library of Congress Cataloging -in- Publication Data Zen ritual : studies of Zen Buddhist theory in practice / edited by Steven Heine and Dale S Wright p cm Includes...
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Báo cáo sinh học: " Genetic characterization of measles viruses isolated in Turkey during 2000 and 2001" pdf
... showing province and number of measles virus isolates obtained during 2000- 2001 Figure virus isolates obtained during 2000 2001 Map of Turkey showing province and number of measles Map of Turkey ... COBL COBL COBL urine urine urine urine urine urine urine throat swab urine urine throat swab nasal swab urine urine urine urine throat swab urine urine urine blood blood urine urine sporadic sporadic ... Phylogenetic analysis of the N gene sequences of wild-type MVs isolated in Turkey Phylogenetic analysis of the N gene sequences of wild-type MVs isolated in Turkey Sequences of the Turkish viruses...
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Từ khóa: what types of plants are found in the amazon rainforestwhat kinds of plants are found in the amazon rainforestwhat type of animals are found in the amazon rainforestprox 1 mems like reactor applied to studies of the prox reaction in micro channelslongitudinal studies of resin composite restoration in posterior teethimpact of genetic polymorphisms on insulin resistancesurvey of chemical differences found in the surfaces of transformed cellsstudies of carotenoid protective functions in bacteriasolid state nuclear magnetic resonance studies of alkali metal ions in nucleic acids and related systemsbuck rongsong liu jiangping shuai jianhong wu huaiping zhu modeling and simulation studies of west nile virus in southern ontario canadasummary of studies of persistent environmental contaminants in terrestrial vertebratesthe role of genetic polymorphismslists of abandoned goods found in the camps at pawnee fork kansas 1867 washita river oklahoma 1868 and summit springs colorado 1869parameter studies of moving force identification in laboratoryhas attracted increasing attention as a component of amperometriclglutamate sensors used in the food industry and clinical biochemistry the precursor of lgoxchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP