Identification of metabolites of meisoindigo from interspecies microsomes and in vivo biological fluids in rats by liquid chromatography tandem mass spectrometry

... IDENTIFICATION OF METABOLITES OF MEISOINDIGO FROM INTERSPECIES MICROSOMES AND IN VIVO BIOLOGICAL FLUIDS IN RATS BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY HUANG MENG (M.Sc., PEKING ... profile was almost absent in the literatures and therefore, the in vitro and in vivo metabolism of meisoindigo were evaluated in this thesis Before introducing the background of meisoindigo in ... excretory 119 metabolites in rat urine H-NMR data for meisoindigo, M1+M2, and M3+M4 meisoindigo 42 and its 115 x LIST OF FIGURES FIG 1-1 Chemical structures of indirubin and meisoindigo 14 FIG...

Báo cáo y học: "Quasi-MSn identification of flavanone 7-glycoside isomers in Da Chengqi Tang by high performance liquid chromatography-tandem mass spectrometry." ppsx

... Determination of Hesperidin in Zhizhu Capsule by HPLC Zhongguo Shiyan Fangjixue Zazhi 2005, 11:5-6 Yang WL, Yu SP, Yang SL, Ren YD, Li YF: Determination of neoheperidin in Fructus Aurantii by RP-HPLC ... 17:359-361 Yang WL, Yang SL, Zhang M, Huang JL: Determination of naringin and neohesperidin in fructus aurantii by RP-HPLC Zhongguo Xinyao Yu Lingchuang Yaoli 2005, 16:261-263 Cuyckens F, Claeys M: Mass ... Shizhen Guoyi Guoyao 2005, 16:280-281 Liang YY, Feng B, Zhu CC, Ni C: Determination of naringin and hesperidin in Fructus Aurantii Immaturus by HPLC Zhongguo Xinyao Yu Lingchuang Yaoli 2006,...

Báo cáo y học: "miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data" pptx

... of all miR loci in the Ciona genome Altogether, miRTRAP generated an apparent false negative rate of approximately 5% and a false discovery rate of approximately 19% To systematically compare ... endogenous human Argonautes and their miRNA partners in RNA silencing Proc Natl Acad Sci USA 2008, 105:7964-7969 33 Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, ... to other genomes will reveal additional novel miRs Materials and methods Library preparation, sequencing and Northern analysis Ciona stage-specific small RNA library preparation and Illumina sequencing...

Isolation and identification of components from ixeris sonchifolia hance as potential anti stroke agents

... Evaluation of antioxidant activities of fractions to isolated from Ixeris sonchifolia Hance extract 44 2.4 Discussion and conclusions Chapter Isolation and characterization of components from ethyl ... Possible anti- coagulation activities of fractions to isolated from Ixeris sonchifolia Hance extract 42 2.3.2 Effects of fractions to isolated from Ixeris sonchifolia Hance extract on the viability of ... fraction of Ixeris sonchifolia Hance 48 55 3.1 Introduction 56 3.2 Materials and methods 56 3.2.1 Isolation of the fractions from Ixeris Sonchifolia Hance extract 56 III 3.2.1.1 Materials and general...

Identification of systems from multirate data

... IDENTIFICATION OF SYSTEMS FROM MULTIRATE DATA MAY SU TUN (B.Sc (Honours) I.C YU, Yangon), (B.E (Chemical) YTU, Yangon) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ENGINEERING DEPARTMENT OF ... nature Because of their usefulness in identification of nonlinear chemical system, this thesis tries to explore the identification of these two models 1.2 Multirate System and Multirate Identification ... from single rate systems in which the inputs and outputs are measured at the same sampling interval, multirate systems are sampled -data systems with non-uniform sampling intervals Multirate systems...

Characteristics of Leachate from Citrus Groves and their Changes in the Collecting Reservoirs in Matsuyama, Japan

... sea level The water in the stream is the leachate from the grove and it flows into a collecting reservoir at the foot of the hill The surface area of the reservoir is about 7300 m2 and the average ... the middle parts of the grove from points Sampling points St.1 and St.2 are in the same stream, and sampling point St.3 is in the other stream The two streams flow together to be one stream and ... runoff characteristics of the materials from citrus grove were investigated and their behaviors in the collecting reservoirs were discussed The main results obtained from the investigation are as...

Tài liệu Identification of Promising Naval Aviation Science and Technology Opportunities docx

... Identification of Promising Naval Aviation Science and Technology Opportunities Committee on Identification of Promising Naval Aviation Science and Technology Opportunities Naval Studies ... auspices of the NSB, established the Committee on Identification of Promising Naval Aviation Science and Technology Opportunities in September 2004 to identify promising naval aviation S&T opportunities ... 2005) 26 IDENTIFICATION OF PROMISING NAVAL AVIATION S&T OPPORTUNITIES As this study was being finalized, the Commander of Naval Air Forces, the Commander of NAVAIR, and the Director of the Air...

Báo cáo khoa học: Oxidative stress induces a reversible ﬂux of cysteine from tissues to blood in vivo in the rat pptx

... whether diamide was also able to affect the thiol ⁄ disulﬁde balance of these organs, and whether cysteine efﬂux to the blood was paralleled by a change in the Cys concentration in other tissues ... maximum total cysteine accumulated in RBCs and plasma is plotted against the diamide dose administered We further evaluated the effect of diamide infusion on various rat organs in order to assess ... accumulation of cysteine within the blood (Fig 4) Our previous studies [22,23] showed a slight increase in hematic cysteine after a single intraperitoneal diamide administration to rats, accompanied...

báo cáo hóa học:" Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients" potx

... Rowland-Jones SJ, Bodmer HC, McMichael AJ, Bell JI: Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA -A2 and influenza A matrix peptide Proc Natl ... have been involved in drafting and critically revising the manuscript LI conceived and coordinated the study and draft the manuscript All authors read and approved the final version of the manuscript ... .CAGCCCCAGXX X .CAGCCCCAGCA T TTCACCCCT CCAC TCAGCCCCAGXX X TCAGCCCCAGXX X TCAGCCCCAGCA T .CAGCCCCAGCA T .CAGCCCCAGCA T .CAGCCCCAGCA T TCAGCCCCAGCA T CTATGGCTACXXX TCAGCCCCAGCA T not available tions 105,...

báo cáo hóa học: " Method optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry" doc

... screw-cap vial for HPLC analysis and 100 µL of the working solution of the internal standard were added to each sample Then the samples were vortex mixed and a 900 µL aliquot was injected into the LC/MS/MS ... some of the structural isomers of prostaglandins, which resulted in the same parent-daughter ion transitions The whole analytical run time, including the recondition step of the column for the ... to the slope and linearity of the calibration curve Due to the low content of matrix compounds in EBC in contrast to other matrix such as urine or plasma which could influence the response of the...

The Production of Ethanol from Maize Cobs and Groundnut Shells docx

... Using the best concentration of H2SO4 (4.5M), a mixture of maize cobs and groundnut shells in the ratio of 1:1, 1:2, 2:1, 1:3 and 3:1 were leached and the hydrolyzed samples were filtered The resulting ... quality of ethanol To determine the effect of different acid concentrations on the hydrolysis 2M solution of concentrated H2SO4 was prepared and 10g of the leached maize cobs and groundnut shells ... 4.5M H2SO4 was used The glucose yield of maize cobs was higher than that of groundnut shells, and ranged from to 0.89g/cm3 for maize cobs (Table1) and to 0.53g/cm3 for groundnut shells (Table2) Table...

Báo cáo khoa học: "Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome" doc

... genetic counseling and possibly clinical management Patients and Methods Family The family studied is of Mexican origin The index case was a 23-year-old female diagnosed with breast carcinoma ... carcinoma of the left breast with combined histological features of lobular carcinoma and infiltrating ductal carcinoma The family history suggested LFS: the patient's father was diagnosed with dorsal ... dorsal soft tissue leiomyosarcoma at the age of 67 years, and a half-sister (from the paternal side) died of bronchioloalveolar carcinoma at the age of 25 years The patient's grandparents died of...

Báo cáo y học: "Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane" pot

... gene/promoter methylation [50]) In addition, the individual composition of cell types in the analyzed SM samples may influence the mRNA expression profile, depending on the inflammatory status and/ or cell ... considerably Results Analysis of inter-individual gene expression variances in rheumatoid arthritis, osteoarthritis, and normal control synovial membrane For the comparison of inter-individual gene expression ... glioma, and inflammatory allergy [17-19] It has been hypothesized that expression variances of regulatory key genes contribute to the individual phenotype of the given disease [17], whether independent...

Báo cáo y học: "Spontaneous internal desynchronization of locomotor activity and body temperature rhythms from plasma melatonin rhythm in rats exposed to constant dim light" docx

... activity (Rw) rhythm from serum melatonin may occur in rats exposed to constant dim red light (LLdim, [15]) The aim of the present study was to further expand this finding by investigating the ... exposure to dim illumination may uncouple several circadian rhythms (e.g., sleep, body temperature, locomotor activity and drinking) in the rat [6] Internal desynchronization has been also reported in ... control, and, although the level of activity may influence the body temperature, the circadian rhythm of body temperature is not a mere consequence of the circadian rhythm of locomotor activity (Review...

Báo cáo y học: "Estimation of stature from the foot and its segments in a sub-adult female population of North India" pps

... and its parts in a sub-adult female population of North India Methods The study was conducted in a selected area of Tehsil Kalka, in the District of Panchkula in Haryana state, Northern India ... Estimation of stature from the foot and its segments in a sub-adult female population of North India Kewal Krishan1,*, Tanuj Kanchan2 and Neelam Passi1 Department of Anthropology, Panjab University, ... located in villages Nanakpur, Marranwala and Bassolan of Tehsil Kalka, District Panchkula in Haryana state of North India for allowing data collection Thanks are also due to the subjects who have...

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