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Molecular biology of the lung and kidney of the african lungfish, protopterus annectens, during three phases of aestivation cystic fibrosis transmembrane conductance regulator, gulonolactone oxidase and p53

Molecular biology of the lung and kidney of the african lungfish, protopterus annectens, during three phases of aestivation cystic fibrosis transmembrane conductance regulator, gulonolactone oxidase and p53

Molecular biology of the lung and kidney of the african lungfish, protopterus annectens, during three phases of aestivation cystic fibrosis transmembrane conductance regulator, gulonolactone oxidase and p53

... in the lung of the control fish were expressed in the lung of fish undergoing the maintenance and arousal phases of aestivation Some of these isoforms, are known to lead to cystic fibrosis lung ... gulonolactone oxidase (gulo) from the kidney of P annectens and to determine the mRNA and protein expression of gulo/Gulo in the kidney and other organs during three phases of aestivation The novel ... among lungfishes The third objective was to sequence the p53 from the lung of P annectens and to determine its mRNA expression levels in the lung and kidney during three phases of aestivation The...
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Molecular biology of glutamate dehydrogenase and glutamine synthetase in two air breathing teleosts

Molecular biology of glutamate dehydrogenase and glutamine synthetase in two air breathing teleosts

... roles of glutamate dehydrogenase and glutamate in nitrogen metabolism………………………………………………… Functional roles of glutamine synthetase and glutamine in nitrogen metabolism…………………………………………………………… Air- breathing ... three isoforms of gs are expressed in the liver, intestine and brain of M albus Terrestrial exposure resulted in a significant downregulation of gs mRNA expression in the liver and intestine of M ... glutamine synthesis involves glutamate dehydrogenase (Gdh) and glutamine synthetase (Gs), this study was undertaken to examine the molecular biology of Gdh and Gs in M anguillicaudatus and M albus,...
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Molecular Biology of Secondary Metabolism - Case Study for Glycyrrhiza Plants

Molecular Biology of Secondary Metabolism - Case Study for Glycyrrhiza Plants

... for crop improvement Trends Biotechnol 26: 531–537 Chapter Molecular Biology of Secondary Metabolism: Case Study for Glycyrrhiza Plants Hiroaki Hayashi Abstract Licorice (roots and stolons of ... al., 2003) Molecular Biology of Secondary Metabolism 99 the high-level accumulation (more than 2% of dry weight) of soyasaponins (Hayashi et al., 2003) Furthermore, enzyme activity of UDP-glucuronic ... condensation of two molecules of farnesyl diphosphate into squalene, a common precursor of sterols and Molecular Biology of Secondary Metabolism mevalonic acid 97 farnesyl diphosphate SQS squalene O 2,3-oxidosqualene...
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Báo cáo y học:

Báo cáo y học: " Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator" pps

... alone, as having a possible role in progression of the inflammatory lung phenotype in CF mice Finally, since both the B6-CF and Bc-CF mice were maintained in identical environments, the differential ... confirming a coordinate increase in levels of the two S100 mRNAs in B6-CF lungs In contrast, similar studies of 20 day-old Bc-CF lungs, which not progress to the inflammatory lung disease phenotype, ... numbers of neutrophils identified by morphometric measures and the increase in levels of expression in the lungs A similar determination of the number of total S100A8 and S100A9 staining cells in the...
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Báo cáo y học:

Báo cáo y học: " Lack of correlation between pulmonary disease and cystic fibrosis transmembrane conductance regulator dysfunction in cystic fibrosis: a case report" pot

... M, Aleksandrov A, Aleksandrov L, Riordan JR: Functional analysis of the C-terminal boundary of the second nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator and ... expect a reasonable patient or their family to object to publication of this case report and any accompanying images Competing interests The authors declare that they have no competing interests Authors' ... have examined the functionality of NBD2 mutants and C-terminal CFTR truncation mutants Although some truncation mutants have normal maturation, most exhibit accelerated degradation of mRNA and...
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Báo cáo y học:

Báo cáo y học: " Elevated expression of both mRNA and protein levels of IL-17A in sputum of stable Cystic Fibrosis patients" potx

... and mRNA levels of IL-22 and IL-23 in sputum of stable CF patients and to relate expression of these cytokines in sputum to the chronicity of airway infection Methods Study population and study ... of both mRNA and protein levels of IL-17A in sputum of stable Cystic Fibrosis patients Respiratory Research 2010 11:177 Submit your next manuscript to BioMed Central and take full advantage of: ... confirmed by significantly increased IL-17A protein levels and in line with previous data on IL-17A expression in CF patients during exacerbation McAllister et al [14] found elevated IL-17A protein levels...
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Báo cáo y học:

Báo cáo y học: " Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells" doc

... distribution of CFTR expression in non-epithelial cells and cells of the immune system implies a variety of functions, including a possible regulatory role in the secretion of cytokines and antibodies ... Especially, inflammation related genes were up-regulated upon the P aeruginosa infection in both WT and CF mice, including 27 interferon-stimulated genes Interestingly, 26 of 27 interferon-induced genes ... "A", or "Marginal" or "M") in over 90% of microarrays were eliminated from further assessment All further analyses were carried out on the remaining 6,474 genes selected using this criterion Genes...
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Báo cáo y học:

Báo cáo y học: " Pulmonary and renal protection: targeting PARP to ventilator-induced lung and kidney injury" pot

... kidney injury Clin Immunol 2009, 130:41-50 doi:10.1186/cc8982 Cite this article as: Matejovic M, Radermacher P: Pulmonary and renal protection: targeting PARP to ventilator-induced lung and kidney ... ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organs Am J Respir Cell Mol Biol 2005, 32:52-58 Koyner JL, Murray PT: Mechanical ventilation and the kidney Blood Purif ... Abbreviations AKI, acute kidney injury; MV, mechanical ventilation; PARP, poly(ADP-ribose) polymerase; PEEP, positive end-expiratory pressure; VILI, ventilator-induced lung injury Competing interests...
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Báo cáo y học:

Báo cáo y học: " Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations" ppsx

... et al.: Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations Respiratory Research 2010 11:137 Submit your next manuscript to BioMed ... Study of Cystic Fibrosis: Pulmonary exacerbations in cystic fibrosis Pediatr Pulmonol 2004, 37:400-6 Cystic Fibrosis Foundation: Clinical practice guidelines for cystic fibrosis Bethesda, MD: Cystic ... Melnick D: The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosis Chest 2005, 128:2336-46...
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Báo cáo y học:

Báo cáo y học: " Glycosylation and the cystic fibrosis transmembrane conductance regulator" docx

... case the authors reported that CFTR contained the insect glycosylation phenotype and was not fully glycosylated As the authors pointed out, the glycosylation phenotype is influenced by the host’s ... early exocytic pathway Traffic 2000, 1:852-870 25 Glick MC, Kothari VA, Liu A, Stoykova LI, Scanlin TF: Activity of fucosyltransferases and altered glycosylation in cystic fibrosis airway epithelial ... of the cystic fibrosis 19 gene: cloning and characterization of the complementary DNA Science 1989, 245:1066-1073 Scanlin TF, Glick MC: Terminal glycosylation in cystic fibrosis Biochim Biophys...
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