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three extensions to the inventory theoretic approach- a transportation selection model, a discrete event simulation of the inventory theoretic approach, postponement from an inventory theoretic perspective

Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot

Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot

... Journal 27 6 (20 09) 6 928 6941 ê 20 09 The Authors Journal compilation ê 20 09 FEBS Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis ... refolding [26 ,27 ]. Conse-quently, we hypothesized that modulation of the cata-lytic potential of the catalytic triad might be accessiblethrough point site mutations of the proximal residue, Tyr190, ... Model structure of hamster NAT2 demonstrates that the residue Y190 is proximal to the catalytic triad. (A) Ribbon represen-tation of the model structure of hamster NAT2. The catalytic triad is colored...
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Báo cáo khoa học: Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution ppt

Báo cáo khoa học: Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution ppt

... cycles of 30 s at 95 °C,30 s at 55 Cand30sat72C, using two primers5Â-GGAATTCCATATGGGAGTCAAGACTGA GAACAAC-3Â and 5Â-CCGCTCGAGTCAACCTCCCGTCTG-3Â. The DNA products were checked on 1.5% agarosegels ... function of human SUMO-2 (Eur. J. Biochem. 271) 4115 Crystal structures of the human SUMO-2 protein at 1.6 A ˚ and 1.2 A ˚ resolution Implication on the functional differences of SUMO proteinsWen-Chen ... determinations.Surface potential and functional difference The mechanisms of protein ubiquitination and SUMOyla-tion are similar, which involve the activating, conjugating, and ligation enzymes...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part1 potx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part1 potx

... Auditor to conduct a management and financial audit of all contracts or agreements awarded by the Hawai`i Tourism Authority to a major contractor every five years. Each audit is to determine if the ... circumvent the State Procurement Code.This is trial versionwww.adultpdf.com Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature ... Revised Statutes, our office conducted a management and financial audit of the Hawai‘i Tourism Authority’s major contracts. A major contractor is one awarded a contract or agreement in excess of $15...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part2 pot

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part2 pot

... Specifically, the authority could not justify the contracts it awarded and did notadequately monitor all contracts. In 1993, the office conducted a Management and Financial Audit of the Hawai`i ... monitored the bureau’scontract.1. Assess whether the Hawai`i Tourism Authority adequately managesits major contracts. 2. Assess the compliance of major contractors with contract provisions and ... UnitedKingdom, Australia, New Zealand, Korea, Taiwan, Hong Kong, and Uruguay. HVCB’s organizational chart is shown in Exhibit 1.4. The Hawai`i Visitors &Convention Bureau is the State s officialtourism...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part3 ppt

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part3 ppt

... 13Chapter 2: The Hawai`i Tourism Authority Enabled the Hawai`i Visitors & Convention Bureau to Exploit State Contract FundingChapter 2 The Hawai`i Tourism Authority Enabled the Hawai`i Visitors ... ConventionBureau (HVCB) to market Hawai`i to leisure and business travelers. A review of the authority’s contract management and internal controlsreveals that the authority failed to safeguard state funds ... Ultimately, the authority’s failure to exertadequate controls allowed HVCB to “run amok” with state contractfunds.1. Inadequate oversight by the Hawai`i Tourism Authority provided the Hawai`i...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part4 potx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part4 potx

... process.However, the fact remains that the arrangement allowed the former governor s office to use HVCB to funnel $23,910 to Joan Bennet and Associates and a separate agreement to pay Joan Bennet and Associatesan ... 32Chapter 2: The Hawai`i Tourism Authority Enabled the Hawai`i Visitors & Convention Bureau to Exploit State Contract Funding The authority also agreed to contracts that did not have clearly ... promoting Hawai‘i in Taiwan and improving and maintaining the image of Hawai`i in Taiwan as a primary visitor and convention/incentive destination. The contract was originally effectivefrom May 1,...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part5 pptx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part5 pptx

... noncompliance that are required to reportedunder Government Auditing Standards. The Auditor State of Hawai`i: We have audited the accompanying statement of financial position of the Hawai`i Visitors ... 42Chapter 3: Financial Audit that we plan and perform the audit to obtain reasonable assurance aboutwhether the financial statements are free of material misstatement. An audit includes examining, ... 37Chapter 2: The Hawai`i Tourism Authority Enabled the Hawai`i Visitors & Convention Bureau to Exploit State Contract FundingOur Management Audit of the Hawai`i Tourism Authority, Report No. 02-04,...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part6 potx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part6 potx

... versionwww.adultpdf.com 43Chapter 3: Financial Audit The Auditor State of Hawai`i: We have audited the financial statements of the Hawai`i Visitors &Convention Bureau (HVCB) as of and for the year ... of the Auditor, State of Hawai`i and the board of directors and management of the Hawai`i Tourism Authority and HVCB and is not intended to be and should not be used by anyone other than these ... Bureau. In April1959, the bureau was incorporated under the laws of the State of Hawai`i (State) for the primary purpose of promoting travel to and among the Hawaiian Islands. In July 1996, the...
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Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part7 docx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part7 docx

... but cannot make a statement as to the workperformed by HVCB’s financial auditor. However, we agree that the State and Legislature should take the appropriate steps to assess the extent of the ... onAgencyResponsesResponses of the Affected AgenciesWe transmitted drafts of this report to the Board of Directors of the Hawai‘i Tourism Authority, the authority’s executive director, and the Department of Business, ... year of the contract period, but stand by ourstatements.We made some minor changes to the draft report for the purposes of accuracy and clarity. In addition, we added a recommendation that the State...
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báo cáo hóa học:

báo cáo hóa học:" Psychometric evaluation of the Osteoporosis Patient Treatment Satisfaction Questionnaire (OPSAT-Q™), a novel measure to assess satisfaction with bisphosphonate treatment in postmenopausal women" potx

... purposes)Health and Quality of Life OutcomesOpen AccessResearch Psychometric evaluation of the Osteoporosis Patient Treatment Satisfaction Questionnaire (OPSAT-Q™), a novel measure to assess satisfaction ... Osteoporosis Patient Satisfaction Questionnaire (OPSAT-Q) is a new measure of patient satisfaction with bisphosphonate treatment for osteoporosis. The objective of this study was to evaluate the psychometric ... the OPSAT-Q as a treatment satisfaction measure in clinical studies of bisphosphonate treatment for osteoporosis and osteopenia. The OPSAT-Q can beused to quantify enhanced satisfaction with improvedbisphosphonate...
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introduction to discrete-event simulation and the simpy language

introduction to discrete-event simulation and the simpy language

... sampling, e.g. to be used for long-run4 # queue length; the arguments Per, Mon and Fun are the sampling period,5 # the monitor to be used, and the function to be called to get the data6 # to be recorded78 ... elegant, and is the more popular of the two main world views today.3 Introduction to the SimPy Simulation Language SimPy (rhymes with “Blimpie”) is a package for process-oriented discrete-event simulation. ... may wish to plot a histogram of the wait times, rather than just computing theirmean. This is possible, via the function Monitor.histogram, which finds the bin counts and places theminto a data...
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Báo cáo lâm nghiệp:

Báo cáo lâm nghiệp: "A change in structural diversity and regeneration processes of the spruce virgin forest in Nefcerka NNR (TANAP) in relation to altitude" docx

... difference in the index was confirmed in the spruce virgin forest in the altitudi-nal range of 1,300–1,400 m.e analysis of the structure of the spruce virgin forest in Nefcerka NNR assessed according ... Education of the Slovak Republic, Project No. 0082-06.A change in structural diversity and regeneration processes of the spruce virgin forest in Nefcerka NNR (TANAP) in relation to altitudeJ. ... 9.3% in the breakdown stage up to 19.1% in the growth stage of the total number of individuals of natural regeneration. e natural regeneration structure of the stud-ied spruce virgin forest Nefcerka...
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Báo cáo khoa học:

Báo cáo khoa học: "Analysis and simulation of the architecture of a growing root system: application to a comparative study of several tree seedlings" ppsx

... Analysis and simulation of the architecture of a growing root system: application to a comparative study of several tree seedlingsM. Colin-Belgrand1L. Pages2E. ... suggested that the shape and the spatial extension of root systems markedly influence the rate and patterns of nutrient uptake from the soil.Many nutrient and water uptake modelshave ... detailed analysis of a growing root system with all its dynamicaspects (Belgrand et al., 1987). It is also a developmental approach: a root is definedas the non-branched...
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Báo cáo y học:

Báo cáo y học: " Intragenic transcriptional cis-activation of the human immunodeficiency virus 1 does not result in allele-specific inhibition of the endogenous gene" pdf

... HOS_A4 cells. Indeed, analysis bysouthern blotting (Figure 3B) and cloning of the integra-tion sites by inverse PCR revealed that the provirus laywithin the HMBOX1 (homeobox containing 1) cellulargene. Allele-specific ... purposes)RetrovirologyOpen AccessResearch Intragenic transcriptional cis-activation of the human immunodeficiency virus 1 does not result in allele-specific inhibition of the endogenous geneAlex De Marco3,4, ... similar in both cell lines: 4 .13 ± 1. 02 forHOS _14 3b and 4 .11 ± 0. 91 for HOS_A4 (p value = 0 .18 )(Figure 6B). Most importantly, the ratio between the intensity of the signal of the two loci was invariably...
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three extensions to the inventory theoretic approach- a transportation selection model, a discrete event simulation of the inventory theoretic approach, postponement from an inventory theoretic perspective

three extensions to the inventory theoretic approach- a transportation selection model, a discrete event simulation of the inventory theoretic approach, postponement from an inventory theoretic perspective

... Three Extensions to the Inventory Theoretic Approach: A Transportation Selection Model A Discrete Event Simulation of the Inventory Theoretic Approach Postponement from an Inventory Theoretic ... handle a wide variety of variables, easily accommodate additional constraints, and guarantee the optimal answer given valid assumptions and accurate data. In contrast to the matrix approach, ... critical to achieving this balance. This paper presents a model that balances transportation and relevant inventory costs to select the optimum speed and reliability of a door -to- door transportation...
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