Báo cáo sinh học: "Analysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publication)" potx
báo cáo sinh học:" Analysis of a survey on young doctors'''' willingness to work in rural Hungary pptx
... rural area: "&apos ;Rural areas' are considered to be thoseareas which are not urban in nature. An 'urban agglomer-ation' refers to the de facto population contained withinthe ... they wanted to work in Budapest,almost 60% said they wanted to work in a county capitaland only 6.5% said they wanted to work in a smaller town.Only two wanted to work in a village. In all, ... areas rural that are not in thevicinity of a city having a medical university and/or hav-ing a high level health care institution.This paper concentrates on potential effects of trainingon...
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báo cáo sinh học:" Reflections on the ethics of recruiting foreigntrained human resources for health" pptx
... remained until the adoption of the WHO GlobalCode of Practice on the International Recruitment of Health Personnel, the key referent in discussions about‘managed HHR migration,’)encourages the establish-ment ... 19(1):1-7.doi:10.1186/1478-4491-9-2Cite this article as: Runnels et al.: Reflections on the ethics of recruiting foreign-trained human resources for health. Human Resources for Health2011 9:2.Submit your next manuscript ... community of theservicestheyneed.” Others saw foreign-trainedhealth professionals as a last resort for filling vacanciesbecause of the effort and resources that were requiredto bring them on board:...
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Báo cáo sinh học: " Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus" doc
... better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these antibodies upon the fusion activity of the F protein. A summary of these resultsis ... of the fusion activity of the panel of mutationsdescribed here revealed that the fusion activity of the F protein is tolerant to multiple changes in the site II and IV/V/VI region. These changes ... of changes tolerated within the F pro-tein. Although the F protein is the only virion surface pro-tein required for fusion and viral entry [25-27], the F protein is also essential for the formation...
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Báo cáo sinh học: " Analysis of machine perfusion benefits in kidney grafts: a preclinical study" doc
... MA, Shenton BK, Balupuri S, Gupta AJ, Asher J, Talbot D:Weight increase during machine perfusion may be an indicator of organand in particular, vascular damage. Ann Transplant 2004, 9:31-32.41. ... group.Functional parametersAnimals were placed in individual metabolic cages forblood and urine collection. Functional parameters weremeasured using an automatic analyzer (Modular auto-matic analyzer, ... was invaluable. Alanine aminopeptidase andb-N-acetylglucosaminidase are found in kidney tubularcell s br ush border and their presence in urine is a com-monly accepted sign of tubular damage...
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Báo cáo sinh học: "Combination therapy: the next opportunity and challenge of medicine" ppt
... Combination therapy: the next opportunity and challenge of medicine. Journal of TranslationalMedicine 2011 9:115.Submit your next manuscript to BioMed Central and take full advantage of: ã Convenient ... other classes of agents [8]. Often CardiacDisease are associated with other metabolic dis eases likehypercholesterolaemia and diabetes; each of them isfurther and effectively treated with the ... breast, ovarian, and head and neck cancer. However, in the last decade, the approachesto cancer therapy have change d. In 1998, the approval of trastuzumab for the treatment of breast cancer...
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Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... CyP's capacity to impair innate resistance to HSV-1 [56,57]. Further study is needed to test thishypothesis. Role of Stat 1 in innate resistance to HSV-1 The biological functions of IFN-α/β and ... CentralPage 1 of 15(page number not for citation purposes)Virology JournalOpen AccessResearch Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1William ... NK cells and/or professional APCs confer innate resistance to HSV-1 infection via the secretion of IFN-γ at early times p.i. The following study was initiated to determine if NK cells provide innate...
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Báo cáo sinh học: " Strategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectra" ppt
... AccessResearch Strategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectraDay-Yu Chao*1, Chwan-Chuen King1, Wei-Kung Wang2, Wei-June Chen 3 , ... III of viral isolates 3H was caused by the value of 0 of dS at the denominator. The positive selection on the domain III isnot surprising since domain III contains the receptor-binding domain ... 225 amino acids in the coding region; the E/NS1 region was 1 239 nucleotides in length covering 4 13 amino acids which included 40amino acids at the N terminal end of NS1 protein, the NS3region...
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Báo cáo sinh học: "Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability, genotypic stability, and overlapping transcripts" ppt
... is the first comparative study of all of the genomic compo-nents of the ORFs from UL146 through UL147A and the first report of multiple overlapping transcripts expressed from this region. The ... nucleotide sequences of the UL146- UL147A region, and in the case of CH1 and CH2Northern analysis of temporal transcriptional pattern of UL146 through UL132Figure 7Northern analysis of temporal ... by sequences from the UL146- UL147 intergenic region and the UL147 ORF. In contrast to the high level of sequence variability among unrelated clinical strains, the sequences of UL146 through UL147A...
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Báo cáo sinh học: "Islands in the sky: the impact of Pleistocene climate cycles on biodiversity" pdf
... [7,10].Furthermore, inference of the number of these refugia and the timing of isolation of populations has, until recently,depended on the construction of gene trees, assumptionsabout whether these trees ... exciting developments that are helping us to under-stand the impact of climate- induced shifts in the Pleistocene on distribution of populations, and thus on speciation,include the use of ecological-niche ... of its possible effect in changing species distributions, and thus on the speciation of organisms. The role of these climatic fluctuations on speciation has been much debated. At one end of the debate,...
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Báo cáo sinh học: "Pitfalls in the phylogenomic evaluation of human disease-causing mutations" potx
... of CL/P. Importantly, none of the variantsidentified resides within the MH1N or homeodomainregions harboring the tooth-agenesis mutations; rather, theylocate to other regions of the protein, ... [1] are shown in Figure 1a (blue arrow-heads). They are all located within the most highly con-served regions of the protein (one in the MH1N domainand four in the homeodomain) and collectively ... harbor the same variant, even when they areunaffected themselves. Most of these variants have beenidentified in only single CL/P cases, making the task of obtaining a statistically robust distinction...
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Báo cáo sinh học : " Notch signaling, the segmentation clock, and the patterning of vertebrate somites" pptx
... including Notch ligand genes and the Hes/her genesthemselves. The role of Notch signaling in patternformation depends on the ways in which these components - and others that modulate their activity ... structures of the trunk. The partsit plays in the early operation of the segmentation clock and the later definition and differentiation of the somites are beginning to be understood.Journal of Biology ... (belonging to either the Delta or the Serrate/Jagged subfamily) on its surface; this binds to the receptor, Notch, in the membrane of the signal-receivingcell and thereby triggers cleavage of Notch, ...
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Báo cáo sinh học: "Trees in the Web of Life" pot
... combining genes withdifferent histories into a single data set will almost certainlyresult in a phylogeny that represents neither the history of any individual gene, nor the history of the ... supporting an organismaltree. For example, because of such highways of gene sharingthese types of analyses group members of the orderThermotogales with the Firmicutes, and the members of the 54.2Journal ... 88::272.http://jbiol.com/content/8/6/54Journal of Biology2009, Volume 8, Article 54 Swithers et al.54.3Journal of Biology 2009, 88::54 transfer, and then using the remaining genes to reconstruct the presumed vertical lines of descent...
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Báo cáo sinh học: " Analysis of larval behaviours underlying the pupation height phenotype in Drosophila simulans and D melanogaster" doc
... placed in the center of a petri dish (10 cm in diameter). Original article Analysis of larval behaviours underlying the pupation height phenotype in Drosophila simulans and ... were introduced through the hole into the lighted cage and the other half into the dark cage. The holes wereplugged with dense foam cylinders. The cages were incubated ... and then discarded. Five days later, one larva of the third instar was carefully picked up, washed in distilled water for a few seconds,dried in absorbent paper and...
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Báo cáo sinh học: "Analysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publication)" potx
... 10.1051/gse:2007029Original articleAnalysis of the real EADGENE data set: Comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (Open Access publicatio n)Florence ... of differentially expressed genes. For each of these steps, the techniques used by the workshop participants will be presented and compared.2. MATERIALS AND METHODS 2.1. Presentation of the data 2.1.1. ... microarrays in total). The EADGENE partners who provided the data were RIBFA and the Roslin Institute. Detection of differentially expressed genes 6372.2. Normalisation of the data 2.2.1. Data quality...
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Báo cáo sinh học: " Analysis of the real EADGENE data set: Multivariate approaches and post analysis (Open Access publication)" doc
... www.gse-journal.orgDOI: 10.1051/gse:2007030Original article Analysis of the real EADGENE data set: Multivariate approaches and post analysis (Open Access publication)Peter Sørensena∗, Agnès Bonnetb,BartBuitenhuisa, ... associations between the genes and the phe-notype of interest. Although the purpose of these methods is the same they arequite different in terms of methodology and in the genes included in the anal-ysis. ... scaled and centred. Data from the E. coli data set is shown on the left, and from the S. aureus data set on the right. Multivariate gene expression analyses 6532. MATERIALS AND METHODSAn EADGENE...
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