... gene regu-lation, by modulating the level of expression and ⁄ ordetermining the specific pattern of expression of a gene [34–39]. To evaluate the relevance of the leader intronin cardosin expression, ... library screening of four full-length genesencoding cardosins A, B, C and D precursors, togetherwith the cloning of a partial sequence of the cyprosin B gene and the isolation of the cyprosin A ... Dzelzkalns et al. (boxes I and III) within the promoter region of the SLG13 gene [40] also appear in the leader intron of the cardosin B gene. (B) A motif found in the S1, SLG, SLR1 and PR5 genes [41,42]...