Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors Implications for the mechanism of traumatic myocardial infarction" pot
Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction" pot
... CentralPage 1 of 10(page number not for citation purposes)Theoretical Biology and Medical ModellingOpen AccessResearch Mathematical model of blunt injury to the vascular wall via formation of rouleaux ... the internal wall [16], also creating conditions for atheromatosis.Therefore, our understanding of the mechanism of blunt trauma to the vascular wall, which takes into account local hemodynamic ... model of traumatic damage to the vessel that takesinto account local rheological and hemodynamic factors could be applied to many internal injuries involving anelastic vessel wall and a blunt traumatic...
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báo cáo khoa học: "Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells" potx
... by heat inactivation and by the presence of the cellulase inhibito r cellobiose. Further, the effect of inhibitors excludes the possibility of alamethicin resis-tance being elicited by any of ... by the pep-taibol alamethicin can be induced in any eukaryote.Interestingly, cell wall degrading enzymes and peptaibolsfrom T. harzanium synergistically prevented spore ger-mination and hyphal ... contributionsSW, AR and MA conceived the study and planned the majority of the experiments. MA conducted all the experiments. HT and ASS took part in the lipid analyses and the interpretation of the results...
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Báo cáo y học: " mathematical model of brain glucose homeostasis" doc
... delivery is taken into account by introducing the last brackets. Model of insulin and glucagon dynamicsInsulin dynamics The concentration dynamics of insulin in segment x, rep-resentatively consisting ... are always others. The same applies to modeling the GIG regulatory system. In this paper, the brain glucosehomeostasis is targeted and modeled as the principle of GIG regulatory system. The relationship ... of the total glucose dose wasassumed to be infused into the venous compartment of the model in the first 30 min, 48 and 32% over the next 2h, respectively, and 8% over the final 30 min. The...
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Báo cáo y học: " Mathematical model insights into arsenic detoxification" pptx
... modified the model by eliminating the urine compartments and the body storage so we could see if the resulting model would be sufficient to capture the results of the in vitro exper iments of Styblo ... relating nutritional status to methylation capacity, and more modeling s tudies to assist in generating hypotheses and in the interpretation of data.Supplementation with vitaminB12willraisetherateofthemethioninesynthasereaction ... connect the dynamics of the methylation reactions in the liver to the presence of arsenicals in the blood and the urine where they are usually measured.AcknowledgementsThis research was partially...
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Báo cáo y học: "Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy" pptx
... contributed to the conception, drafting and writing of the manuscript and to revising it for important intellectual content. HK and SS contributed to the drafting and development of the manuscript and to ... factors contributing to the potential for systemic side effects. Ashort-half life and high clearance rate reduce the expo-sure of the ICS to the systemic circulation, therebyimproving the safety profile. The ... deficiency should prompt the physician to consider a primary cause of the patient’s symptoms.TestingSeveral endocrine tests have been used for the screening and diagnosis of AS. The insulin-induced...
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Báo cáo y học: " Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations." ppsx
... textural properties of polymer gels composed of poly(methylvinylether-co-maleic anhydride) and poly(vinylpyrrolidone): Rheological and mathematical interpretation of textural parameters. JPhar ... 8:12http://www.aidsrestherapy.com/content/8/1/12Page 6 of 10-75°C depending on the melting point of the gellingagent. Additional excipient (Vitamin E, Vitamin EAcetate, Butylated hydroxyanisole or Butylated hydro-xytoluene) ... [1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylfor-mazan] assay and histology.Rabbit Rectal Irritation StudyA ten day repeat dose toxicology study in New Zealandwhite rabbits following rectal administration of placeboformulations...
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Báo cáo y học: "Intraoperative PaO2 is not related to the development of surgical site infections after major cardiac surgery" ppt
... contributionsJB and ET had full access to all of the study data and takes responsibility for the integrity of the data and the accuracy of the data analysis. Both authorscontributed equally to the study. ... and for the first 6 postopera-tive hours in a n effort to decrease SSIs. In contrast to the findings of Belda et al. [2], clinicaltrials by Pryor et al. [4] and, more recently, by Meyhoffet ... reduction in their incidence in some types of surgery however there exist somediscrepancies in this respect. The aim of this study was to analyze the relat ionship between PaO2values and SSIs in cardiac...
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Báo cáo y học: " Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection" pptx
... non-exclusive factors may explain the strong anti-HIV-1 activity of P5 reported here. Amino acids 628 to 663 of peptide P5, containing the calcium-binding site,are essential for binding to the NHR ... content and the threenon-polar residues facing the hydrophobic cavity,together with the structure of the calcium-binding site, aretherefore likely to be responsible for the high anti-HIVactivity ... calcium-binding site and the hydrophobiccavity-binding domain and does not exhibit any anti-HIV-1 activity. The low antiviral activities of P7 peptide indi-cated that the C-terminal cytoplasmic tail in...
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Báo cáo y học: "Nebulised heparin: a new approach to the treatment of acute lung injury" pdf
... trial of nebu-lised heparin in acute lung injury. Crit Care 2008, 12:R64.2. Geiser M, Schürch S, Gehr P: Influence of surface chemistry and topography of particles on their immersion into the ... hasnot yet been achieved; important additional work remains to be done. The following questions need to be answered. As the pro-coagulant state in the alveolar space begins in the early phases of ... it be assessed in order to initiate heparin administration as rapidly as necessary? Howcan dosage of the drug be titrated to achieve maximal local effects without the risk of systemic complications?...
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Báo cáo y học: "Polysaccharopeptides derived from Coriolus versicolor potentiate the S-phase specific cytotoxicity of Camptothecin (CPT) on human leukemia HL-60 cells" pps
... used annexin V/PI flow cytometry analysis to quantify the viable, necrotic and apoptotic cells. The expression of cyclin E and cyclin B1 was determined with annexin V/PI flow cytometry and western ... μg/ml) for 72 hourswas able to enhance the cytotoxicity of CPT (1 μM) to the HL-60 cells. The total viable, necrosis and apoptosis cellspopulation were determined by annexin V/PI flowcytometry ... 3H-thymidine uptake and prolonged DNA synthesis time (Ts) in HL-60 cells. PSP-pretreated cells enhanced the cytotoxicity of CPT. The sensitivity of cells to the cytotoxic effects of CPT was...
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