Báo cáo y học: "Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation" ppt
Báo cáo y học: "Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation" ppt
... Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation. Critical ... 14:R21http://ccforum.com/content/14/1/R21Page 11 of 11RESEARC H Open AccessMild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral ... sought to examine whether hypothermia or the combination of hypothermia with anesthetic post-conditioning with sevoflurane affect cerebral inflammatory response after cardiopulmonary resuscitation.Methods:...
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Báo cáo y học: "Mild hypothermia after near drowning in twin toddlers" pps
... to hypothermia depends, among other factors, on the amount of time that elapses before induction of mild hypothermia [1,3,6].Induced mild hypothermia for cerebral protection after neardrowning ... hypothermia on admission cor-related with poor outcome, suggesting that spontaneous hypothermia may be a result of major brain injury [11]. In the present case report, hypothermia on the scene and onadmission ... outcomes. In patients affected by braininjury with a Glasgow Coma Scale score from 3 to 8, inducedmild hypothermia for 24–48 hours yielded controversial find-ings [11,12]. In these patients hypothermia...
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Báo cáo Y học: Conditionally immortalized adrenocortical cell lines at undifferentiated states exhibit inducible expression of glucocorticoid-synthesizing genes pot
... were inducible in the three cell lines in tem-perature- and /or dibutyryl cAMP-dependent manners.Notably, these cell lines displayed distinct expression pat-terns of the steroid 1 1b-hydroxylase ... genes indicatethat the cell lines have the property of adrenocortical cells.Especially, expression of the e ndogenous P450c21 gene in the established cell lines contrasts strikingly with the characteristics ... with those of nontransgenic animals,suggesting that the ts oncogene developed no tumor in the adrenal g lands at body temperature. As judged by the haematoxylin/eosin staining, zonation of their...
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Báo cáo y học: " Ethnobotany, diverse food uses, claimed health benefits and implications on conservation of barley landraces in North Eastern Ethiopia highland" ppsx
... filtered in the afternoon, itwould be ready to serve in the morning of the next day.While the other forms of tela are brown, korefe is lighter in color because the asharo is not roasted very dark.Normally, ... gather information on the ethnobotany, the utilization of barley and how barley end-uses influence the maintenance of landrace diversity.Results: According to farmers, barley is the “king of ... con-sistently mentioned by the farmers interviewed in the study with r egards to food preparation from barley wasthat the manual processing of the grain (i.e. dehulling,grinding, sieving, roasting)...
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Báo cáo y học: "A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice" pps
... developinhibitors of other PDE classes to be used in combination with PDE4 inhibitors, with the goal of maintaining or enhancing efficacy while reducing the dose-limiting sideeffects associated with ... PDE4 only inhibitors. Thisstudy therefore examined the in vitro and in vivo potency of a combination of phosphorothioate AONs directedagainst PDE4B/4D and PDE7A subtypes. These AONsincorporate ... http://respiratory-research.com/content/10/1/39Page 6 of 14(page number not for citation purposes)Inhibition of inflammatory mediators by combined 4B/4D and 7A AONs in NHBE cellsFigure 2Inhibition of inflammatory mediators by combined 4B/4D...
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Báo cáo y học: " Mild induced hypothermia after out-of-hospital cardiac arrest: persisting doubts about patient safet" pps
... ‘rebound hyperthermia’ frequently observed after rewarmingmay decrease the beneficial effects of MIH on brain injury andhas not yet been clearly explained [10]. An additional use of the cooling system ... temperature of 37°C for several hours) after rewarming appears an efficient technique to avoid‘rebound hyperthermia’ and the activation of inflammatory cytokines, but deserves further study (unpublished ... (unpublished data). Hypothermia alone significantly reduces the number of and the severity of motor seizures, and exhibits anticonvulsanteffects in addition to the large use of benzodiazepines forsedation...
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Báo cáo y học: "Mild therapeutic hypothermia shortens intensive care unit stay of survivors after out-of-hospital cardiac arrest compared to historical control" potx
... shivering. All patients completed therapeutic hypothermia without complications or overcooling. With the exception of therapeutic hypothermia, there was no further dif-ference in the standard of intensive ... score was lower in the control group. Finally, we cannot exclude the fact that the introduction of therapeutic hypothermia itself has focused the attention of the physicians in charge to a more ... 3One-year survival of the study populationOne-year survival of the study population. Kaplan-Meier 1-year survival analysis of both study groups.Key messages• The major determinants of short intensive...
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Báo cáo Y học: Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the a or b catalytic subunit potx
... Ca2+-binding loops [36]. In the absence of Ca2+-binding to the low affinity sites, the CaM-binding domaininteracts with the exposed side of the CnB-binding helix [26].Calcium binding to the ... shown in the crystal structure, the N-terminus of CnA interacts with the C-terminal half of CnB as part of a CnB-binding cleft,suggesting that the interaction of the CnA N-terminus with CnB is involved ... affinity sites on CnB disrupts the interaction between the CaM-binding domain and the CnB-binding helix and increases the affinity of the CaM-bindingdomain for Ca2+/CaM [25,26]. The regulation of...
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Báo cáo y học: " Mild autonomic dysfunction in primary Sjögren''''s syndrome: a controlled study" pptx
... following:activity of vigorous intensity on at least 3 days, achieving a min-imum of at least 1,500 multiples of resting metabolic state(MET)-minutes/week; or 7 or more days of any combination of walking, or ... ratio, and may be interpreted as a HRV fac-tor, possibly reflecting sympathetic/parasympathetic balance.Interestingly, factor 1 scores were higher (less abnormal) in patients with Raynaud's ... variability analysisTime domain analysis The mean and time domain HRV parameters of the RR interval[18], including the standard deviation (SDNN), the proportion of successive intervals differing by...
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Báo cáo y học: " Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers" pptx
... where they are intrinsically involved in leukocyte-endothelial cellinteractions. In this pilot study we hypothesised that mild episodes of tourniquet induced forearm ischaemia-reperfusioninjury ... described previously [4]. Trapping of leukocytes to the endothelium would result in a decrease in the number of leukocytes leaving the arm [4]. Evidence of increasedleukocyte trapping in blood vessels ... opportunity to investigate othermarkers of endothelial damage to support these findings.Further scientific research may also highlight potentialpoints of therapeutic intervention for pathophysiologicalconditions....
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