Báo cáo y học: " The Peter Pan paradigm" pot

... Obviously, thesediseases would present with very heterogeneous pheno-types because the more severe the delay, the earlier the average temporal state of the tissue. The prototypical disease in the Peter ... How-ever, the hypothesis that the altered water balance andresultant inflammatory lung disease is due solely to lackof CFTR in the post-natal lung is contradicted by both the CF phenotype in the ... recessivedisorder yet the human phenotype can occur in the absence of homozygous mutations in the CFTR gene [31]and the heterozygous knockout mice have a unique lungphenotype [32]. Expression during embryonic...

Báo cáo y học: " The ARDS Support Center" potx

... the information at the layperson’s level, andthey have succeeded in simplifying relatively complex topicsto the extent possible. Information is also provided on the many physical, cognitive, ... their families. Here, patrons relate their stories, offersupport, and ask for help with the complex andmultidisciplinary recovery after discharge from the ICU. Wefound especially notable the ... family members’, as outlined in their MissionStatement. The site is solely directed at ARDS and does notcover any other critical care topics, even those possibly seenin conjunction with ARDS. The...

Báo cáo y học: "The challenge of sepsis" potx

... sepsis,thereby reducing mortality from sepsis by 25% over5 years. An unprecedented 11 organizations sponsored the evidence-based and expert opinion guidelines. Another of the stated goals of the ... management.Unfortunately, clinicians change very slowly. Historically,transfer of research from the bench to the bedside is along, tortuous process – one that is not driven by anythingvery clear and ... 31:1250-1256.6. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B,Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collabo-rative Group: Early goal-directed therapy in the treatment ofsevere...

Báo cáo y học: "The rhythms of life" pot

... 1960, which many people in the fieldconsider as the start of modern chronobiology. This year’ssymposium not only provided insights into the latest researchof circadian rhythms in cyanobacteria, ... replicate their DNA more and more in the oxidativephase, a concomitant increase in the mutation rate occurred. The protection of the integrity of the genome may be arecurring theme in rhythmic ... rhythmically.Ryoichiro Kageyama (Kyoto University, Kyoto, Japan) hasanalyzed in detail the basic helix-loop-helix transcriptionfactor Hes7, whose rhythmicity of expression is dependenton the segmentation...

Báo cáo y học: "The Utstein template for uniform reporting of data following major trauma: A valuable tool for establishing a pan-European dataset" docx

... move towards a whole-system approach to data collection, for it is only in the complexity of our trauma patients, and the multitude ofinterventions they are exposed to, that the true future oftrauma ... pathology and radiologysystems already collect much of the diagnostics, morbid-ity and outcome data on these patients. We have enoughcomputer processing power and data storage for theseneeds. New ... Physiological data, drug andblood product administration can all be tagged electroni-cally, as can the patient's position within the hospital.Other databases, such as ICU, pathology and...

Báo cáo y học: "The Systemic Inflammatory Response Syndrome (SIRS) in acutely hospitalised medical patients: a cohort study"

... identified by two or more symptomsincluding fever or hypothermia, tachycardia, tachypnoea and change in blood leucocyte count. The relationship between SIRS symptoms and morbidity and mortality in ... and they would be missed if SIRS were used as the only way to identify infected patients. If the main pur-pose was to identify patients with a high risk of mortality, the question is whether ... stay, diagnosis ondischarge, 28 day mortality and, if possible, the course ofmortality. The follow-up registration was made by chartreview by one of the authors (PC), with evaluation by aspecialist...

Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"

... difficulties” was the most used Index-category in the “all other” group with nearly 5% of the total. Approximately half of all patients in the youngestage group had “all other” medical problems ... S29 (34)Other musculoskeletal symptoms L29 (396)Other 465 10 2.3 10 400Endocrine/metabolic symptoms T29 (11)Urinary/male genital symptoms U29 (7) Y2 9 (5)Pregnancy/female genital symptoms W29 ... thisgroup. In the youngest age group (0-9 years), neurologi-cal symptoms dominated in both genders, with 32% of the 180 situations among the boys, and 43% of the 123situations among the girls.Table...

Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

... diagnosis. The increased effort required for the study consisted of only a 5-minute debriefing to fill out the standardized MET form on each patient and a weekly 1-hourCommentary The evolving story of ... teams, mayprovide just such a method. The rationale for the developmentof METs rose from observations that, in the majority ofpatients, premonitory signs and symptoms of cardio-pulmonary instability ... increasingly recognizing engagement in quality improvement asa distinct career pathway. Involving such physicians in medicalemergency teams will likely facilitate the dual roles of these as aclinical...

Báo cáo y học: "The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care unit"

... to the ICU during the studyperiod only had their first ICU admission selected for review.Patients were included in the study cohort if their ICU stay waslonger than one day in duration and they ... that capture physiological and ventilation data. Thesedata were validated by nursing or respiratory therapy staff onat least an hourly basis by examining the degree to which theyare representative ... dataand assume responsibility for the integrity of the data and the accuracy of the analysis.References1. Himmelstein DU, Jones AA, Woolhandler S: Hypernatremicdehydration in nursing home patients:...

Báo cáo y học: "The Impact of a Nationwide Antibiotic Restriction Program on Antibiotic Usage and Resistance against Nosocomial Pathogens in Turkey"

... restricted for the first three days of therapy by NARP, the consumption of these quinolones was unsurprisingly high. Besides that the use of oral quinolones for maintenance may contribute to the significant ... committees many years before the initiation of the NARP. Even in these selected centres already apply-ing local antibiotic restriction policies the utilisation of many of the restricted antibiotics ... performed in four year period, which included two years before and after of the initiation of NARP in 2003. The study in-cluded the data obtained from all of the four univer-sity hospitals, and...

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