... Ichiyama H, Onodera S, Nishihira J, Ishibashi T, Nakayama T,Minami A, Yasuda K, Tohyama H: Inhibition of joint inflammation and destruction induced by anti-type II collagen antibody/lipopolysaccharide ... Y, Nakamura H, Obata K, Yamada H, Hayakawa T,Fujikawa K, Okada Y: Matrix metalloproteinases and tissueinhibitors of metalloproteinases in synovial fluids frompatients with rheumatoid arthritis ... fibroblasts. RA synovial fibroblasts arekey mediators in the pathogenesis of RA because they have the ability to attach to the articular cartilage and invade carti-lage [45]. MIF is highly expressed...