... 1 of 11(page number not for citation purposes)Theoretical Biology and Medical ModellingOpen AccessResearch Bringing metabolic networks to life: integration of kinetic, metabolic, and proteomic ... kinetic, thermodynamic, metabolic, and proteomic data.The structure of the metabolic system (i.e., stoichiometries and enzyme regulation) needs to be known, and the reactions are modelled by convenience ... ()()11111−−()θθθˆθyyR y () () ( ).θθ θθθ≈+ −()12R y θRmi y θθθθθθθθ() ()()()() (*())2111111=+()×−+−−−−+ CRCRRCyy Cyy y T y T y −−−−−−()=+()()112111113()T y θθθθ()()...