... IL-12 in system lupus erythematosus. II: IL-12 production in vitro is correlated nega-tively with serum IL-10, positively with serum IFN-gamma and negatively with disease activity in SLE. Cytokine ... and analyzedusing bioinformatics tools. Since interactions among TNF, IFN, -estradiol (E2), and IFN may regulate the expression of interferon-inducible (IFI) genes, stimulating and co-stimulatingexperiments ... cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16,IFI27, IFI30, IFI35, interferon-induced transmembrane protein1, ISG15, IRF7, OAS1, OASL, GBP1, and GBP2) in PBMCsupon...