Báo cáo y học: "Increased sinusoidal flow is not the primary stimulus to liver regeneration" pps

... increased sinusoidal flow, we hypothesized in the present study that, according to the “ flow theory” of liver regeneration, it is the increased sinusoidal flow initself, which is the primary stimulus ... proinflammatory cytokines using multiplex flow cytometry by the xMAP (TM) technology. Cytometry Part A 2006, 69A:391-395.23. Benjamini Y, Hochberg Y: Controlling the false discovery rate - A ... increased sinusoidal flow per se and hence the shear-stress stimulus on the endothelial surface within the liver remnantwhich is the main stimulus to regeneration. In order to test this hypothesis...

Báo cáo y học: "Leg-length inequality is not associated with greater trochanteric pain syndrome" pps

... interests.Authors' contributionsNAS developed the study hypotheses and analysis plan, par-ticipated in the statistical analysis, and drafted the manuscript.WH participated in the data collection and manuscript ... participated in the study design and manuscriptpreparation. MY conducted the statistical analysis and partici-pated in manuscript preparation. JCT participated in the studydesign, analysis, and interpretation ... present study. The funding source – National Institutes of Health – did not contribute to the study design, data collection, analysis, or interpretation of data, nor to the writing of the manuscript...

Báo cáo y học: "TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies" pot

... cardiovascular mortality may bemissed, because patients dying of CVD earlier in the disease course are not part of their cohort. Thishypothesis was corroborated by our results in the RAcohort, which ... RA.In order to further unravel the eventual associa tionbetween TRAF1/C5 locus and mortality, we hypothe-sised that this risk would not be restricted to RA.Therefore, we also genotyped TRAF1/C5 ... equilibrium.This indicates that there was no selection of the protec-tive genotype in the RA or non-RA cohort. This makesan early death in t he risk genotype carriers unlikely andfurther supports the...

Báo cáo y học: "Increased blood flow prevents intramucosal acidosis in sheep endotoxemia: a controlled study" pptx

... ran-domly during the respiratory cycle were considered and werenormalized to body weight to yield Q. Intestinal blood flow wasmeasured by the electromagnetic method (Spectramed BloodFlowmeter ... ascribed to flow redistribu-tion from mucosal to serosal layers [13]. Conversely, Revellyand colleagues described flow redistribution from serosa to Table 1Systemic and intestinal hemodynamic ... (∆PCO2) is common in experimentalendotoxemia. However, its meaning remains controversial because it has been ascribed to hypoperfusion of intestinal villi or to cytopathic hypoxia. Our hypothesis...

Báo cáo y học: " Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe" ppt

... severity of the shock, as well as the nonblinded nature of the study, however, may have played a confounding role. Nevertheless, if the increase in forearm fl ow is indeed evoked by the more ... protection of the endothelium and the cardiovascular system, but that this is antagonized by concomitant pronounced hyperglycemia. e antagonistic eff ect between insulin signaling and hyperglycemia ... blood fl ow is an interesting one, which is important to take into account when analyzing results of studies on the topic. In this light, the weak correlation in the current study by Žuran and...

Báo cáo y học: " Insulin-treated diabetes is not associated with increased mortality in critically ill patients" ppt

... whether or not they had ahistory of insulin-treated diabetes prior to ICU admis-sion. The a priori defined outcome parameters for thisanalysis included the degree of organ dysfunction/failureas ... as reflected by highersimplified acute physiology system II (SAPS II) and SOFA scores, and more likely to be receiving hemodialysis than the other patients. During the ICU stay, more patients ... insulin-treated diabetesare more severely ill on admission to the ICU andmore likely to have or develo p renal failure and to require hemodialysis than patients with no history ofinsulin-treated diabetes.•...

Báo cáo y học: "Increased plasma homocysteine levels in patients with multiple sclerosis and depression" ppsx

... Moderately disabled MS patients with elevated Hcy levels are particularly prone to develop depressive symptomatology. Further study is warranted in order to elucidate the prognostic and therapeutic ... prior to their inclusion in the study. The meanduration of the disease was 9.8 ± 5.9 years and disabilityaccording to Extended Disability Status Scale (EDSS) was3.2 ± 1.7 points. None of the ... purposes)Discussion The present study addressed the issue of Hcy metabolismin MS and investigated whether Hcy levels are related to depression in this disease. It is concluded that Hcy is increased in patients...

Báo cáo y học: "Advanced paternal age is a risk factor for schizophrenia in Iranians" pps

... andpsychotic behaviour: definitions and methodological issues. Can JPsychiatry 2002, 47:527-537.7. Ban TA: Neuropsychopharmacology and the genetics of schizophrenia: ahistory of the diagnosis ... methyla-tion), and the metabolic level (for example, synthesis ofpurines and deoxythymidine triphosphate (dTTP) andS-adenosyl methionine, the cofactor that donates amethyl group). Hence, it would not be ... (CAG)n[39]. It is of notethat this study was limited to (CAG)nrepeat occur-rences, and we do not know whether the increasedmutation rate extends to other sequences. However,other studies...

Báo cáo y học: "Increased levels of circulating microparticles in primary Sjögren''''s syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity" pdf

... activating factor receptor expression onperipheral lymphocytes associated with increased diseaseactivity in primary Sjogren's syndrome and systemic lupus ery-thematosus. Ann Rheum Dis 2007, ... applicable; pSS = primary Sjogren's syndrome; RA = rheumatoid arthritis; SLE = systemic lupus erythematosus; SLEDAI = SLE disease activity score.Arthritis Research & Therapy Vol 11 No 5 ... ani-onic phospholipids such as PS, they could be consumed bysPLA2. This enzyme is increased in level and activity in someinflammatory diseases and catalyzes hydrolysis of aminophos-pholipids, including...

Báo cáo y học: " All that glitters is not gold - founder effects complicate associations of flu mutations to disease severity" ppt

... the casefor HA-Q310 H and PB2-K340N but not HA-D239N orHA-D239G. While founde r effect mutations cannotautomatically be linked to phenotypes simply byincreased occurrence, they may nevertheless ... effects. Only few strainsare available with HA-D239N, however, they seem to resemble more closely the scattered distribution of HA-D239G.This phylogenetic clustering is further supported by the temporal ... compared to the other 2 mutations.Conclusions The interpretation of effects of mutations on observedpatient phenotypes is notoriously difficult. Besidesunderlying conditions of the patient, facto...

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