... arthritis. It remains to be determined whethercirculating IL-1F8 can contribute to joint inflammation in rheumatoid arthritis.IntroductionUntil recently, the IL-1 family of cytokines included four ... Internal Medicine, University Hospital and Department of Pathology and Immunology, University of Geneva School of Medicine, Geneva, Switzerland2Division of Genomic Medicine, University of Sheffield, ... correlatewith inflammatory status. Interestingly however, we observedhigh IL-1F8 levels in several serum samples in all groups. In conclusion, IL-1F8 exerts proinflammatory effects in primary human joint...