... in populations fromthe US, Canada and Spain, and nearly identical to datareported from Great Britain and New Zealand [5-10]. How-ever, the carrier frequency of the 1858T allele in RA patientswas ... Grumley JA, Kingsley GH, Fisher SA: Association of R602W in a protein tyrosine phosphatase gene with a highrisk of rheumatoid arthritis in a British population: evidence foran early onset/disease ... prepared the manuscript. SK, SA,MW and CB participated in the collection of clinical data and the recruitment of patients into the study. UW and HH partici-pated in the design of the study, statistical...