Báo cáo y học: "Formulas Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study" docx

... effects of vasopressin were similar tothose of epinephrine in the management of cardiac arrest and pulseless electrical activity (PEA) [17]. On the other hand,most of the porcine models of cardiac ... [30].These seemingly contradictory findings may be explained by the fact that many of the studies do not take into account asubgroup analysis such as the distinction between VF, PEA and asystole. ... the American Heart Associ-ation Councils on Epidemiology and Prevention, Stroke and Cardiovascular Nursing and the Interdisciplinary WorkingGroups on Quality of Care and Outcomes Research and Atherosclerotic...

Báo cáo y học: "Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases'''' pps

... protein. Syk includes two tandem SH2 domains and a tyrosine kinase domain. Interdomain A is between the two SH2 domains, and interdomain B is between the tyrosine kinase domain and C-terminal ... fragments. In an antigen-induced airway in ammation model in rodents, the Syk inhibitor BAY 61-3606 blocked both degranulation and lipid mediator and cytokine synthesis in mast cells and suppressed ... proinﬂ ammatory cytokines and enzymes, and contribute to the in ammatory process and the eventual destruction of the joint. A number of studies have claimed a role for Syk in the function of...

Báo cáo y học: "Human protein C concentrate in the treatment of purpura fulminans: a retrospective analysis of safety and outcome in 94 pediatric patient" pps

... data analysis and interpretation, and writing of the manuscript. DF, MS and FW were involved in data analysis and interpretation, and writing of the manuscript. WK was involved in studydesign and ... data analysis. BE was involved in study design and datacollection. UM was involved in data management, statistical analysis and data interpretation. RS was involved in study design, data analysis, ... analysis, and writing of the manuscript. All authors read and approved the finalmanuscript.Competing interestsAV was a member of a Baxter advisory board and received as such an honorarium. At the...

Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"

... Despite the retrospective study design and the limited possibility of interpreting these find-ings and their causes, this rate indicates that patients suffering from late hip joint infections and ... reactions), and general complications (drain-ing sinus, pneumonia, etc.). Despite the retrospective design of our study and the limited possibility of in- terpreting these findings and their causes, ... H, Akpinar S, Tandogan RN, Alparslan M. Two-stage treatment of chronic staphylococcal implant-related infections using Vancomycin- impregnated PMMA-Spacer and rifampicin containing antibiotic...

Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc

... re-entry into the cell cycle by these growth-arrested preadipocytes,RB is phosphorylated by cyclin ⁄ cyclin-dependentkinase holoenzymes, releasing the E2F complex and thereby resulting in activation ... versus intake causes an increased storage of the excess energy in the form of intracellular triacylglycerol droplets in adipose cells,leading to an increased fat mass and ultimately result-ing in ... modern era, yet existing medicines to combat this globalpandemic are disappointingly limited in terms of safety and effectiveness. The inadequacy of currently available therapies for obesity has made...

Báo cáo y học: "Alcohol use and abuse in training conscripts of the Hellenic navy" pps

... place at the training campus of the Hellenic Navy on the island of Poros in November1998. Groups of 20–30 people completed the question-naires in the presence of a psychiatrist and two psycholo-gists ... with the results of other studies among youngpeople in Greece [38] and the increasing frequency of binge (which means that there is a consume of great quan-tities of alcohol in a few hours) drinking ... twofold one, i.e. to meas-ure problematic drinking among training conscripts of the Hellenic Navy both by adult and by adolescent standards, and to measure levels of hidden alcoholism in the...

Báo cáo y học: "JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin" ppsx

... melittin and BV-inducedinhibition of NO and PGE2 generation.Effect of melittin and bee venom on LPS and SNP-induced phosphorylation of MAPKsFigure 1Effect of melittin and bee venom on LPS and ... sulfhydryl group of p50 and/ or IKKα and IKKβ, and that these inhibit inflammatory reaction in the development of rheumatoid arthritis [4,5]. In the presentstudy, we further found that melittin and ... activation of MAP kinase may be also involved in the anti-inflammatory effect of melittin and bee venom.Methods: The anti-inflammatory effects of melittin and bee venom were investigated in cultured...

Báo cáo y học: "Clinical importance and impact on the households of oseltamivir-resistant seasonal A/H1N1 influenza virus in healthy children in Italy" ppt

... in the laboratory assays. All authors read and approved the finalmanuscript.AcknowledgementsThis study was supported in part by MedImmune, and in part by the ItalianMinistry of Health (Bando ... demographic and clinical character-istics of the children with A/H1N1 influenza infection,by the p resence or absence of the H27 5Y mutatio n, and the impact on the households of the infection on theirhouseholds ... 2008-2009 in Italy. The influenza A virus-positive samples underwent neuraminidase gene analysis usingpyrosequencing to identify mutations H27 5Y and N294 S in A/H1N1, and E119V, R292K, and N294 S in...

Báo cáo y học: "Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses" docx

... ubiquitous in nature, and is an accurate indicator of the cleanliness of indoor environments in urban areas. CD14 recognizes and binds to the endotoxin. A C → T polymorphism at position159 of the 5′ ... that many otherfactors involving the in utero environment and fetal geneby environment interactions can affect fetal programming and the subsequent development of disease. The maternal–fetal interface ... infections. The limitations of thisstudy included follow-up of only 71% of infants (allowingfor potential bias) and no direct measures of infectiousburden. Additionally, the cohort’s primary study designwas...

Báo cáo y học: "Number needed to treat = six: therapeutic hypothermia following cardiac arrest – an effective and cheap approach to save lives" pdf

... as translation and transcription of patho-genic proteins. Additionally, it has anti-apoptotic, anti-inflam-matory and anti-coagulatory properties and can reduceoedema formation [8].There ... tolerance to mild inducedhypothermia after out -of- hospital cardiac arrest using an endovascular cooling system” by Pichon et al. in the previousissue of Critical Care [1] points to a very relevant ... this therapy is notevidence-based and that it is technically too difficult. Mildtherapeutic hypothermia is definitely underused post cardiac arrest, and many patients who need not die are dyingbecause...

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