... inhibitor binding to the enzyme in a simple bimolecular reaction, similar to what we discussed in Chapters 8 and 9. 318 Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis. Robert ... experiment can be used to great advantage. See Malcolm and Radda (19 70) and Anderton and Rabin (19 70) for examples of this approach. 10 .5.3.3 Affinity Labels. Covalent modifying groups can often ... Biochem. Pharmacol. 25, 2695.Cha, S., Agarwal, R. P., and Parks, R. E., Jr. (19 75) Biochem. Pharmacol. 24, 218 7.Copeland, R. A. (19 94) Methods of Protein Analysis, A Practical Guide to L aboratoryProtocols,...