Báo cáo y học: "Early and transient reverse transcription during primary deltaretroviral infection of sheep" ppt

... that they exist as DNA and/ orRNA species. Their polymerases are reverse transcriptasesdevoid of 3' exonucleolytic activity, and genetic variabilityis thereby a part of their way of life ... number not for citation purposes)RetrovirologyOpen AccessResearchEarly and transient reverse transcription during primary deltaretroviral infection of sheepCarole Pomier1, Maria T Sanchez ... (RT)-associated substitution. Primary infection of a neworganism necessary involves allogenic cell infection and thus reverse transcription. Results: Here we demonstrate that the primary experimental bovine...

Tài liệu Báo cáo Y học: Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA pdf

... methyl groups are always introduced, oneslowly by Dnmt3a or by de novo methylation catalyzed byDnmt1 and the second one very fast. Therefore, this effectcan only double the rate of DNA methylation, ... Dnmt3a and Dnmt3benzymes (in addition to Dnmt1) are required for mainten-ance of the methylation at certain DNA sequences. A role of Fig. 3. Stimulation of Dnmt1 and Dnmt3a by fully methylated ... hemimethylated DNA is much higher [18],generation of one hemimethylated site will immediately leadto a second methylation in the unmodiﬁed strand of this sitein the presence of Dnmt1. Kinetically...

Báo cáo y học: "Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading" ppt

... The use of an animal model opens up the possi-bility of studying the early stages of disease progression and the regional pattern of matrix degradation by compar-ing diseased and healthy joints ... How-ever, in spite of reasonable effort, we have not been able todetect YKL39 in canine chondrocytes and databases. Theupregulation both of YKL40 in early stages of dog OA and of YKL39 in late-stage ... stages of OA pro-gression by means of early and late disease markers isquite an attractive prospect. According to our data, col II and YKL40 are good candidates for use as robust, early and sensitive...

Báo cáo y học: "Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia" pot

... study data and takes responsi-bility for the integrity of the data and the accuracy of the dataanalysis. He helped conceive of the study and participated inits design and coordination and ... respectively, early from LS RA, and early or LS RAfrom healthy synovia. We identified several gene clusters and distinct molecular signatures specifically expressed during earlyor LS RA, thereby suggesting ... identified bycomparison of profiles of early, LS RA and healthy synovia werelinked to the biological processes involved in each situation.Results Three combinations of 719, 116 and 52 transcriptsdiscriminated,...

Báo cáo y học: "Early and late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions: a review of 400 cases" potx

... 15/400(3.7%). Factors adversely affecting in hospital mortality and 3-month mortality included age, Karnofsky Perfor-mance Status and delay between diagnosis of pleural effu-sion and pleurodesis. The ... [10,11]. The mortalityrate within 3 months was 3.7%, with Karnofsky Perfor-mance Status and delay between diagnosis of pleural effu-sion and pleurodesis to play a statistically significant role.According ... contributionsNB conceived of the study and participated in its design and coordination. CAparticipated in the design of the study and performed the statistical analysis.FP, GS, DP, AK, KL and IK took part...

Báo cáo y học: "Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol: retrospective analysis of 3441 on- and off-pump coronary artery bypass grafting procedures" doc

... technique, 30-day and 1 year mortality inwomen measured 1.7%. Mortality in men was 2.1% after30 days and 3.7% after one year (not significant).Gender specific mortalityThirty day mortality in women ... aftercoronary artery bypass grafting in women depends on the surgicalprotocol: retrospective analysis of 3441 on- and off-pump coronaryartery bypass grafting procedures. Journal of Cardiothoracic ... patients.BackgroundEvery year, 215,000 women die of cardiovascular dis-eases and approximately 30,000 women die of MI inGermany. Coronary artery bypass graft ing (CABG) isone of the most frequent...

Báo cáo y học: "Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers" doc

... Switzerland2Department of Medicine, Section of Rheumatology, University of Florence, Italy3Department of Internal Medicine and Public Health, University of L’Aquila, Italy4Department of Internal ... [30]. Hypoxia increases thesynthesis of VEGF in a variety of cell types via an accumu-lation of the transcription factor hypoxia inducible factor 1[31]. In addition, a variety of cytokines ... 19:1187-1194.14 Kim YM, Jang JW, Lee OH, Yeon J, Choi EY, Kim KW, Lee ST,Kwon YG: Endostatin inhibits endothelial and tumor cellularinvasion by blocking the activation and catalytic activity of matrix...

Báo cáo y học: "omparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi" pps

... encodingfungalysins and subtilisins was recently moni tored in A.benhamiae by cDNA microarray analysis during growthon keratin, and also during cutaneous infection of gui-nea pigs [8]. Interestingly, ... of dermatophytes to specifically infect superficial hoststructuresmaybesupportedbythepossessionofabroad repertoire of genes encoding hydrolytic enzymes,the expression of many of which was ... Secretion of proteases and other hydrolyticenzymes by A. benhamiae was proven experimentally by a global secretome analysis during keratin degr adation.Molecular insights into the interaction of A....

Báo cáo y học: " Foot and ankle surgery in Australia: a descriptive analysis of the Medicare Benefits Schedule database, 1997–2006" potx

... 47678);(iii) lesser toes: including primary and secondary repair of flexor and extensor tendons, tenotomy, correction of clawtoes, hammertoes and hyperextension deformity(item numbers 49800, 49803, ... (consisting of the number of proceduresperformed by sex, age-group and calendar year) wasextracted individually and exported into Microsoft Excel(Microsoft Corp, Redmond USA) for analysis. MBS ... highly prevalent in the general community and asubstantial proportion of people seek surgical treatment to alleviate foot pain and deformity.However, the epidemiology of foot and ankle surgery...

Báo cáo y học: " Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross-sectional University of Zaragoza study" docx

... the aetiology of burnout subtypes. However,confirmation of these types of associations does notcome under the scope of this study. The main aim of Montero-Marín et al. BMC Psychiatry 2011, 11:49http://www.biomedcentral.com/1471-244X/11/49Page ... understanding of the type of professional burnout present in employees of a univer-sity organisation in Spain and support the idea of adifferential characterisation of burnout syndrome byproviding specific ... study was carried out on a multi-occupational sample of randomly selected universityemployees (n = 409). The presence of burnout types was assessed by means of the “Burnout Clinical SubtypeQuestionnaire...

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