... purposes)RetrovirologyOpen AccessResearchRole of the long cytoplasmic domain of the SIV Env glycoprotein in early and late stages of infectionAndrei N Vzorov*1, Armin Weidmann1,4, Natalia L Kozyr2, ... and the fusion activity of the Env glycoprotein [10,11]. SIV and HIV Env glycoproteins contain a relatively long cytoplasmic domain (150–200 amino acids) comparedwith most other retroviral Env ... purposes)Background The Env glycoproteins of retroviruses play an importantrole in the initial steps of infection involving the bindingto cell surface receptors and entry by membrane fusion. The Env glycoprotein...