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Báo cáo khoa học: "Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants" pptx

Báo cáo khoa học:

Báo cáo khoa học: "Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants" pptx

... iNO therapy, and the present studysuggests that iNO may influence clinical outcomes as well.This should be a consideration in our armamentarium in the battle against AHRF. The recognition that ... effect on mortality” [13]. The concern in the neonatal literature that iNO may induceintracranial bleeding in preterm infants was not supported in this study. Disturbances in platelet aggregation ... bleeding time have been demonstrated in neonates [14,15]. In the present study there was noevidence of increased intraventricular hemorrhage in the iNOgroup. The mechanism by which NO inhibits...
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Báo cáo y học:

Báo cáo y học: "Inhaled nitric oxide in acute respiratory distress syndrome with and without septic shock requiring norepinephrine administration: a dose–response study" ppt

... probablyoccurred in two of our previous studies [4,23]. Another rea-son for determining the inspiratory NO concentration in thisway was the method of NO administration used. Continu-ous administration ... decrease in MPAPand an increase in PaO2/FiO2 in the range of 0.15 to 150ppm inhaled NO.Toxic effects of increasing concentrations of inhaled NOAs shown in Table 3, methemoglobin and NO2 ... dopamine, epine-phrine or norepinephrine tend to reinforce hypoxic pulmonary vasoconstriction. In the present study, patientswith circulatory shock receiving vasodilating inotrops wereexcluded in order...
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Báo cáo y học:

Báo cáo y học: "Inhaled nitric oxide reverses cell-free hemoglobin-induced pulmonary hypertension and decreased lung compliance. Preliminary result" ppt

... collected 10 min after the finalααHb infusion. Inhaled NO, in concentration of 5 ppm, wasthen administered for 10 min and data were recorded. The inhaled NO was discontinued for 10 min, after which ... USA.AbstractBackground: In order to test the hypothesis that inhaled nitric oxide (NO) reverses the pulmonaryhypertension induced by αα-diaspirin crosslinked hemoglobin (ααHb), were studied anesthetized pigsthat ... an intravenousbolus of pancuronium bromide (0.08 mg/kg) and fentanyl(30 µ g/kg) was administered. Anesthesia was then main-tained with a continuous infusion of fentanyl (5 µ g/kg/min).The...
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Báo cáo y học:

Báo cáo y học: "Inhaled nitric oxide in persistent pulmonary hypertension of the newborn refractory to high-frequency ventilatio" ppsx

... 2hof INO therapy in 61.1% of the responders, and the remaining responded gradually during the INO treatment.However, OI and a/A ratio remained almost the samethroughout the treatment in the non-responders ... Tolazoline wasunsuccessfully attempted in two neonates in the referringhospitals. Methemoglobin and nitrogen dioxide weremaintained below 5% during INO therapy. The averageage when INO was ... 139:252A.9. The NINOS Study Group: Inhaled nitric oxide for near-term infantswith respiratory failure. N Engl J Med 1997, 336:597–604.10. Roberts JD, Fineman JR, Morin FC, et al: Inhaled nitric...
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Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx

Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx

... short interfering RNA (siRNA) in human cells. BothHO-2 mRNA and protein are expressed in the eight human cancer celllines examined, and HO-1 expression is detectable in five of the cell lines,including ... andHO-2 proteins. The intensity representing HO-1 or HO-2 protein was normalized with respect to the intensity of the b-actin signal. The ratioof each normalized value to the control value in siRNA-untreated ... were maintained in suspension culture (Fig. 1), although HO-1 isexpressed in two other cell lines, YN-1 and KG1, thatwere also maintained in suspension culture. Theseresults suggest that the...
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

... calciumchannels and may thereby reduce the serotonin-induced sustained increase in [Ca2+]i, as has beenshown for endothelin-1-induced Ca2+increase in Rat1cells [29]. Whether HEK293 cells express ... (F340) increases, whereas the fluorescence intensity at 380 nm (F380) decreases upon the binding of Ca2+. The change in the ratio ofF340 ⁄ F380 determined the change in Ca2+concentrationinside ... domain, did not increase the basal or serotonin-induced ERK1 ⁄ 2 phosphorylation. The ERK1 ⁄ 2 phos-phorylation was inhibited in the presence of the calcium in ux inhibitor, CAI. The endogenous...
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Báo cáo khoa học:

Báo cáo khoa học: "Combining information from surveys of several species to estimate the probability of freedom from Echinococcus multilocularis in Sweden, Finland and mainland Norway" docx

... itremained at 0.98 in Finland. By increasing the sensitivityofthesurveillanceinrodentsinSwedentothesamelevel as in Finland, the annual sensitivity of this surveil-lance system component increased ... 1. The prior probability that the country is in fected at the beginnin g of y+1isgivenby the function [15]:PriorPInf PostInf PIntro PostPInf PIntroyyy yy   11 1()Where PriorPInfy+1is ... in year y.PIntro The annual probability of introduction and establishment of the infection in the countryPostPFree The posterior probability of freedom from infection in the countryPriorPInf...
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Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain pdf

... extents in the FNR–FMN subdo-main interface, including the interface in NOS (Fig. 8).Point mutations that neutralize charge pairing or intro-duce charge-repelling interactions may increase the Fig. ... autoinhibitory insert elements, or elsewhere in the enzyme.Changing the set point for KeqA may in uenceelectron flux through the NOS flavoprotein in interest-ing ways (Fig. 6). For example, the ... the interaction between the FMN subdomainand the FNR subdomain, although some may also in uence the rate of electron import into the FMN sub-domain and the resulting formation of FMNH2. The extent...
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báo cáo khoa học:

báo cáo khoa học: "D -Cn S1 α another allele associated with a decreased synthesis rate at the caprine α locus -casein S1" ppsx

... that the frequencies of as,-CnOwere 0.05 in Alpine and 0.03 in Saanen. Because in their data aS1-CnD was not distin-guished from as,-CnO, these values in fact ... is the seventh allele identified at the goat as!!asein locus. Itsfrequency in the large Alpine herd of Moissac (N = 198) was 0.025. It was also observed in the Saanen ... to their daughters, an observation at variancewith the conclusions of the present note. Re-examination of the surviving dam-daughterpairs among the 7 considered by these...
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