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Báo cáo y học: "Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: lessons for the future in pathogenesis" pps

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Báo cáo y học: "he discovery, positioning and verification of a set of transcription-associated motifs in vertebrates" pps

... behaving similarly totheir non-CG containing peers (green), with the methylatedregions showing the classic suppression of CG containingmotifs. Interestingly, the CpG (putatively unmethylated)regions ... radically different from the other plots: most obviously the CG containing motifs arebehaving separately from their non-CG peers. More subtly,there are many more motifs in the top left side of the ... interested in pre-dicted CpG islands in the context of the whole genome, butrather in predicting methylation status in the context of pre-viously defined upstream regions. Figure 3 shows the...
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Báo cáo y học: " Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report." pptx

... origin[4]. In some cases zygomycetes may infect lung cavitiesfollowing pulmonary tuberculosis [8]. There is only onereport of pulmonary zygomycosis and M. tuberculosisinfection occurring ... [10].Bronchoscopy may be useful in establishing the diagnosisof zygomycosis via BAL or transbronchial biopsy. The endobronchial findings of zygomycosis include the pres-ence of granulation tissue, gelatinous ... simultaneously in a patient with acutemyeloid leukaemia [9]. Pulmonary zygomycosis usually presents as a diffusepneumonia causing cough, fever and haemoptysis.Involvement of the mediastinal structures...
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Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

... beendetermined by combining two-dimensional1H-NMR and molecular dynamics.Introduction of conformational restraint through cycliza-tion has become a standard strategy in medicinal chemistry for increasing ... U73122 on inositolphosphate formation and polyphosphoinositide breakdown inducedby ODN, OP and cyclo128OP in cultured rat astrocytes. The cellswere incubated for 5 min with ODN, OP or cyclo128OP ... concentrations and polyphosphoinositideturnover in cultured rat astrocytes.MATERIALS AND METHODSMaterialsAll amino-acid residues, preloaded 4-hydroxymethyl-phenoxymethyl-copolystyrene-1%-divinylbenzene...
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Báo cáo y học: " Upregulation of Bax and Bcl-2 following prenatal cocaine exposure induces apoptosis in fetal rat brain" doc

... and protocols used in the present study were approved by the Institutional Animal Care and Use Committee of Loma Linda University and followed the guidelines put forward in the National Institutes ... whether cocaine leads to changes in Bcl-2 family protein levels in fetal brain, we examined the Bcl-2 and Bax protein expression. As shown in Figure 4, Bax protein was minimally detected in ... that cocaine affinity for brain tissue is similar in the fetus and dam after subcutaneous injection of cocaine, whereas the cocaine metabolite benzoylecgonine concentrations in fetal brain were...
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Báo cáo y học: "Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28– T cells in ankylosing spondylitis" ppt

... cellpopulation in the healthy control individuals tested.Intracellular staining for perforin and IFN-γ was performed in activated cells to determine the number of cytokine pro-ducing cells. Production ... CD4+CD28–NK T cells initiating and sustaining immune responses, and providing a linkbetween the adaptive and the innate immune systems,may hold true for AS disease.Competing interestsNot declared.Acknowledgements The ... using a modified metrologyscore, but they are independent of age and duration ofankylosing spondylitis. CD4+CD28–T cells produce IFN-γ and perforin, and thus they must be consideredproinflammatory...
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Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt

... control mAb for 30 minutes. 3H-thymidine was added and B cells were incubated for 24 hours. The incorporated radioactivity was quantified. Fold increase in 3H-thymidine incorporation in response ... stimulation in the synovium. Taken together, inter-action between chemokine and chemokine receptor mightplay roles not only on B cell migration into the synovium, butalso B cell activation in the synovium. ... was supported in part by grants -in- aid from the Ministry of Health, Labor and Welfare, and the Ministry of Education, Science, Sports and Culture, Japan, and the Japanese Ministry of Education,...
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Báo cáo y học: "Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity" potx

... to increase its DNA bindingactivity [27], it will be interesting to test whether the ERK activity could be induced by NBS1 overexpression,leading to the phosphorylation of HSF4b.HSPA4 and ... migration/invasion, soft agar colony formation, and gelatinzymography assays were performed.Results: Here we show that heat shock protein family members, A4 and A14, were induced by NBS1overexpression. ... Nagayama M: Increased invasion and matrixmetalloproteinase-2 expression by Snail-induced mesenchymaltransition in squamous cell carcinomas. Int J Oncol 2003, 22:891-898.17. Yang MH, Chang SY,...
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Báo cáo y học: "Traditional-Medical Knowledge and Perception of Pangolins (Manis sps) among the Awori People, Southwestern Nigeri" ppsx

... ofAframomummeleguetaRoasted, grinded into powderyformUsed to make incision on the lower eyelids, left eye ofpangolin for making incisionon the left eyelid, ditto for the right eyePython Eye3 FemalereproductiveorganEjection ... literature and revision of the manuscript. TAA participated in datacollection during the preliminary and main survey and in drafting the manuscript. Both authors read and approved the final manuscript.Competing ... breeding of pangolin whil e subjecting the scales and other parts to laboratorystudies to determine the bioactive constituents.IntroductionThroughout human history, and in practically everyhuman...
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Báo cáo y học: " Physiotherapy-supervised mobilization and exercise following cardiac surgery: a national questionnaire survey in Sweden" pot

... physiotherapists. The most commonly describedtechnique for getting out of bed was lying on the side,placing one or both hands in front o f the body, leaningforward and pushing up to a sitting ... on days 2 and 3, and typicallyone treatment on days 4 and 5. Physiotherapy treatmentwas never given during the evenings. On Saturdays, phy-siotherapy treatment was reported to be routinely givento ... and formulate internationallyaccepted guidelines for cardiac surgery patients.ConclusionsThis survey provides initial insight into physiotherapymanagement in Sweden.Theresultsofthesurveyindicatethatthereareonlysmall...
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Báo cáo y học: " Poly-substance use and antisocial personality traits at admission predict cumulative retention in a buprenorphine programme with mandatory work and high compliance profile" ppt

... chroma-tography-mass spectrometry (GC-MS) [19]Discont inuation of treatment is always decided jointlyby the senio r consultant psychiatrist and the staff afterinforming the other authorities and the ... completing detoxification the subjects wentthrough a phase of psychological testing and psychiatricassessment including psychiatric screening for psychia-tric symptoms and personality disorders: (SCID-II),SCL-90, ... counselling is decided by the home town services.Beingdischargedfromtheprogramrequiresthatthepositive urine screen at the unit is verified by an inde-pendent laboratory finding. Urine samples...
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