... Pax-6alters DNA-binding specificity of the resulting proteins[39]. Alternative splicing of the transactivationdomains in Pax-8 [40], the POU homeodomain familyprotein Pit-1 [41] and the zinc finger ... osmolytes glycine-betaine, myo-inositol, tau-rine, sorbitol, and glycerophosphorylcholine [2–4].Accumulation of glycine-betaine, inositol, and sorbitolis transcriptionally regulated and depends, ... cotransfected V5-epitope-taggedTSC22D2-4 in pcDNA5FRT vector together with aFlp recombinase expression vector to insert TSC22D2-4 into the FRT site in exchange for the LacZ gene. The transgenic...