... is the region with the lowest degree of identity between the two isoforms of the enzyme, the region encompassing the Arg-rich clus-ter is almost fully conserved in RnLGS, again indica-ting ... system, also invol-ving other regions of the protein, which is regulatedby binding of Glc6P to the enzyme. Interestingly,6-deoxyglucose did not induce the export of nuclearHsMGS, indicating that, ... with COS-1cells transfected with the GFP–HsMGS construct, indi-cating the presence of an NES in the sequence of HsMGS or the involvement of an NES-containingprotein in its export from the nucleus...