báo cáo khoa học: " Years of life lost to prison: racial and gender gradients in the United States of America" pps

... importance. The goal of the present study was to determine the differences in the number of years of life lost to imprisonment in the United States population by gender and race.Methods The number of years ... then used to compute the life table value of the total remaining years of life and the corresponding life expectancy in each state for eachage group. Total life expectancy at birth or any other ... (disa-bility) and prison-free life expectancies were estimated bydividing the years lived in each age range of the life tableinto these two states using prevalence of imprisonment by gender and race. These...

báo cáo khoa học: " Conifer R2R3-MYB transcription factors: sequence analyses and gene expression in wood-forming tissues of white spruce (Picea glauca)" pot

... [18,30,31], including the bHLH-interaction and calmodulin-binding motifs in the DNA-binding domain [28,29], and the repressiondomain pdLNLD/ELxiG/S in the C-terminus [7]. In ourstudy, the spruce ... twentyamino acid motifs in the variable C-terminal region, of which nine were previously unreported. The amino acidmotifs in the DBD and in the C-terminal region are useful to better characterise the ... relative to the translation start codon. The boxes and dotted line above the sequences show the predicted helix and turn structures in the R2 and R3 regions of the MYB domain. Stars show positions of...

báo cáo khoa học: " MoccaDB - an integrative database for functional, comparative and diversity studies in the Rubiaceae family" pdf

... administration,integrated the bioinformatics tools in the application. VPserved as the principal investigator of the project, per-formed the data analysis, assisted in the designing of the database, and drafted the ... used in large-scale genomic studies owing to their ubiquitous dis-tribution in both protein-coding and non-coding regions and the high degree of length polymorphism among indi-viduals [5]. The ... grant funding. The authors thank D. Crouzillat of Nestlé for permit-ting the integration of Nestlé's primer data into MoccaDB and Y. Pournin and A. Egorov (system administrators) for technical...

Báo cáo khoa học: Alternative splicing produces an H-protein with better substrate properties for the P-protein of glycine decarboxylase doc

... the alternative H-proteins, both the naturallyoccuring FtGLDHAA and the artiﬁcial AtGLDH1AA,are indeed exclusively due to the insertion of twoadditional alanyl residues into the N-terminus ... for producingrecombinant H-proteins leaves a small extension of four amino acid residues at the N-terminus of eachrecombinant protein after removal of the His tag (Fig.S4). The kinetic differences ... H-protein,FtGLDHAA, harbours two additional alanine residuesvery close to its N-terminus, and is by far the mostdominant H-protein type in leaf mitochondria of theseplants. Because of photorespiratory...

Báo cáo khoa học: "Using Conditional Random Fields to Extract Contexts and Answers of Questions from Online Forums" docx

... clustered segments intosubtopics, and identified responding segments of the first segment in each sub-topic by assuming the first segment to be focus. In (Nenkova and Bagga, 2003; Wan and McKeown, 2004; ... request information in the form of an an-swer. The sentence containing request focus iscalled question. Context are the sentences contain-ing constraints or background information to the question, ... 2006). The graphical representation of a Skip-chain CRF given in Figure2(b) consists of two types of edges: linear-chain (yt−1 to yt) and skip-chain edges (yi to yj).Ideally, the skip-chain...

báo cáo khoa học: " All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein" pdf

... an inverted microscope.Assessment of cytotoxic effect of ATRA in combinationwith imatinib The cytotoxic interactions of imatinib with ATRA wereevaluated using the isobologram of Steel and ... All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cellline by affecting on the expression of survivin and Bax protein. Journal of Experimental ... and imatinib The result of isobologram was showed in Figure 5B. Alldata points in the combination fell within the envelope of additivity, the area surrounded by the three lines, sug-gesting that...

báo cáo khoa học: " EDR2 negatively regulates salicylic acid-based defenses and cell death during powdery mildew infections of Arabidopsis thaliana" docx

... antigen binding protein [28]. In the CERT protein, the PH domain binds PI-4-P as does the EDR2 PH domain[29]. In addition, the START domain of the CERT proteinbinds to ceramides. From these properties, ... localizes to the plasma membrane. Bars = 13.4 μm.Binding of the EDR2 PH-domain to lipidsFigure 7Binding of the EDR2 PH-domain to lipids. GST-tagged EDR2 PH domain was affinity purified and used to ... purposes) The PH domain of EDR2 specifically binds to phosphatidylinositol-4-phosphate in vitro The PH domain of EDR2, expressed as a PH domain-GSTfusion protein, had strong in vitro binding affinity...

Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf

... organelles.Therefore it could be used to study the involvement of these proteinases in protein degradation and the processing of invariant chain. An assay combi-ning a new monospeciﬁc CatE antibody and ... Other studies have util-ized a speciﬁc inhibitor of CatE, the Ascaris pepsininhibitor, which inhibits pepsins and CatE [33], butdoes not affect other types of aspartic proteinasesincluding ... method for the quantitation of microgram quantities of protein util-izing the principle of protein-dye binding. Anal Biochem72, 248–254.N. Zaidi et al. Determination of cathepsin E and D activityFEBS...

Báo cáo khoa học: "An Architecture for Dialogue Management, Context Tracking, and Pragmatic Adaptation in Spoken Dialogue Systems" pot

... set of if-then heuristics to determine whether to send through the command or to intercept the utterance and notify the Dia- logue Manager to initiate a repair dialogue with the user. The ... speech for permitting interruption by the user, when to initiate repair dialogues, and how often to back- channel. 1.2 Context Tracking The Context Tracker maintains a record of the discourse ... Language Interpretation fails to parse the output of SR. Rather than continuing the flow on to- wards the back-end, the Dialogue Manager can re-consult SR for other hypotheses. Alterna- tively, the...

Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt

... Microsequencing analysis of the MREa-binding proteins.(A) The N-terminal sequence of the 82-kDa band was identical to amino-acid positions 6–16 of the Ku-80 protein. (B) The 70-kDa banddid not ... Coomassieblue staining, the bands were sliced out of the gel and subjected to automated amino acid sequencing.Construction of the IR Ku-80 gene and the truncatedKu-80 (DKu80)For the double-stranded RNAi ... will also be of interest to examinewhether additional proteins bind to the other three MREs in the WD promoter, and if so, to determine the precisemechanisms by which such proteins modulate...

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