... to each serotype of the virus (present in all strains of the serotype), and (d) unique to each individual viral strain’s genome(present in the strain and absent from all otherstrains). The results ... is in order to determine whe-ther it is, in fact, the optimal solution. For instance, a par-ticular set may exceed the minimum values required of a, b and c and, in fact, have values A, B and ... encephalitis, and dengue fever. One ormore of the four serotypes of the dengue virus areendemic in many parts of the world, including all of south-east Asia, parts of Africa, and Southern and Central...