... role, 187 , 188 mitogen-activated protein kinaseregulation of signaling, 188 , 189 osterix induction, 189 retinoblastoma protein regulationof signaling, 188 signal transduction, 186 , 187 osteoclast ... factorregulation,interferon-a, 203, 204interleukin-1, 202interleukin-4, 202interleukin-6, 202, 203interleukin-11, 203macrophage colony-stimulatingfactor, 200, 201osteoprotegerin, 201RANKL, 200transforming ... 70differentiation and bone morphogeneticproteins,Cbfa1 role, 187 , 188 mitogen-activated protein kinaseregulation of signaling, 188 , 189 osterix induction, 189 retinoblastoma protein regulationof signaling,...