báo cáo khoa học: "Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?" docx

... correlated expression of informative genes.© 2010 BioMed Central LtdPredicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?Takayuki Iwamoto and Lajos Pusztai*CO ... breast cancer is a single disease, and all Abstract A large number of prognostic and predictive signatures have been proposed for breast cancer and a few of these are now available in the clinic ... classiﬁcation for certain tumors, most prominently breast cancer. Breast cancer used to be considered as a single disease with variable histological appearance and variable expression of...

Báo cáo khoa học: "Bony metastases from breast cancer - a study of foetal antigen 2 as a blood tumour markerl" doc

... CA15.3: Cancer antigen 15.3; CEA: Carcinoembryonicantigen; PBC: Primary breast cancer; LAPC: Locally advanced primary breast cancer; ABC: Advanced breast cancer; PICP: Carboxyterminal propeptide of type ... levels of FA-2 in different stages of breast cancer and examines its role as a marker of bonemetabolism in metastatic breast cancer. MethodsPatientsBlood samples were obtained with informed ... significantly elevated in cancer patients when compared to normal women and this wasdue to marked elevation in women with metastatic breast cancer (Table 2). Women with metastatic disease had a much...

Báo cáo khoa học: "Predictive factors for breast cancer in patients diagnosed atypical ductal hyperplasia at core needle biopsy" doc

... clinical and radiological examination, includ-ing mammography and ultrasound. The radiologicalappearance of the lesion was characterized according tothe American College of Radiology Breast Imaging ... clinico-pathologic andradiologic findings that can help discriminate betweenADH and DCIS are valuable in planning patient manage-ment.Although some variables like lesion size, combined mass,and ... Identification of patients with ADH diag-nosed by CNB who can be spared surgical excision is anarea of active investigation. However, the clinical, radio-logic, and pathologic parameters on...

Báo cáo khoa học: "Caecal metastasis from breast cancer presenting as intestinal obstruction" doc

... reported a case of oesophageal perforation in a patient with oesophageal metastasis from breast. Carefulevaluation of gastrointestinal tract in patients with advanced breast cancer receiving chemotherapy ... role of cytokeratins 20 and 7 and estrogen recep-tor analysis in separation of metastatic lobular carcinoma of the breast and metastatic signet ring cell carcinoma of thegastrointestinal tract. ... infiltrating ductal carcinoma of breast. Awareness of this possibility will aid in appropriate management of such patients.BackgroundMetastasis from the breast cancer to the gastrointestinaltract...

báo cáo khoa học: "Hypersensitivity reaction and acute immunemediated thrombocytopenia from oxaliplatin: two case reports and a review of the literature" docx

... M, Chiesa MD, Copercini B, Tomasello G, Brighenti M,Passalacqua R: Oxaliplatin-induced hemolytic anemia during adjuvanttreatment of a patient with colon cancer: a case report. Anticancer Drugs2007, ... Hsueh2*AbstractBackground: Oxaliplatin is a platinum compound used in the treatmen t of gastrointestinal malignancies, includingcolorectal cancer. The incidence of hypersensitivity reaction in patients ... antibody. Allauthors participated in drafting and editing the manuscript. All author s readand approved the final manuscript.Competing interestsThe authors declare that they have no competing interests.Received:...

Báo cáo khoa hoc:" Mammary tuberculosis mimicking breast cancer: a case report" ppt

... with indurated tissue, often with fistulaformation, but is rarely associated with pain and breast discharge. In its advanced form, breast tuberculosis ischaracterized by invasion of the skin, with ... surgery.Case presentation A 73-year-old woman, with an unremarkable medical his-tory, was admitted to hospital complaining of a palpablelump located in her right breast. Upon physical examina-tion, ... physical examination and laboratory data, a preliminary diagnosis of breast cancer was made and thepatient underwent lumpectomy and sentinel lymph nodebiopsy.Frozen section of the specimen revealed...

báo cáo khoa học: " Barriers to research utilization and research use among registered nurses working in the care of older people: Does the BARRIERS Scale discriminate between research users and non-research users on perceptions of barriers?" pptx

... it appears as RNsworking in the care of older people face more barriersthan RNs working in hospitals. One reason might be thatthe average age of RNs working in the care of older people in Sweden ... practice. Being aware of rele-vant research is the first stage in implementing findingsaccording to Rogers' Innovation-Decision process [8].Access to research findings at the work place ... has also beenidentified as a determinant of research uptake in the care of older people [31]. The statistical analyses demonstratedthat the scale detected certain differences betweenresearch...

Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx

... production,thus driving autoimmune skin in ammation [102].Patients with rosacea have abnormal in ammationand vascular reactivity in facial skin. These individualshave high levels of cathelicidin and higher ... antibacterial properties of cultured com-posite keratinocyte grafts. Ann Surg 235, 113–124.37 Midorikawa K, Ouhara K, Komatsuzawa H, KawaiT, Yamada S, Fujiwara T, Yamazaki K, Sayama K,Taubman MA, ... [13]. Cathelicidins killGram-positive and Gram-negative bacteria andTrypanosoma cruzi. Similar to defensins, cathelicidinsparticipate actively in linking innate and adaptiveimmunity and in modulating...

Báo cáo khoa học: "Flowering and cone production variability and its effect on parental balance in a Scots pine clonal seed orchard" docx

... was done following par-titioning variance and covariance componentsobtained from a one-way ANOVA and multi-variate analysis of variance (MANOVA) of pollen and seed cone ... synchro-nization of a clone with other clones exist-ing in an orchard (Askew and Blush, 1990).The range of variation of the index calcu-lated for female flowering was narrower andranged ... rather late, probablydue to a cold spring with many late frosts.On average, female flowering started 1.25days earlier than male flowering in 1990,and 1.09 days earlier...

Báo cáo khoa học: "Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: Do we have indications for individual risk stratification?" pdf

... evaluation of proximal, distal and circumferen-tial resection margins and intra- and extramural vascularand perineural invasion. Nodal staging included histolog-ical evaluation of all detected ... hematoxylin and eosin staining.Pathological Staging/GradingPathological staging included ypTNM stage according tothe current TME classification[14], tumor differentiationgrading, evaluation ... To date, standardized appli-cation of adjuvant CT is guaranteed only withinrandomized clinical trials and clinicopathologic indica-tions for risk stratification in patients after multimodaltherapy...

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