báo cáo khoa học: " Recent advances in the genetics of language impairment" docx

... difficulties controlling the movement and sequencing of orofacial muscles, causing deficits in the production of fluent speech. In- depth studies of the KE family showed that, in these individuals, speech ... understanding of language disorders and improve our understanding of the biological foundations of language acquisition.© 2010 BioMed Central Ltd Recent advances in the genetics of language ... path-ways and the inherent difficulties of precisely defining them in the laboratory.FOXP2 in the braine expression of FOXP2 is not limited to the brain but is also seen in several other organs,...

Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps

... ChemotherapyAn area of particular interest is the use of SLN biopsy in patients undergoing neoadjuvant chemotherapy, because the number of patients choosing this option isincreasing.Until recently, ... 5years at the multivariate analysis [237]. In the US this information has resulted in a rapidincrement of Breast Fellowship, recognizing that appro-priate training is one of the key factors in improvingquality ... directing planes of sur-gery during the exc ision. This in turn is helpful in guar-anteeing both negative margins and an adequatecontour of resection in order to minimize the volume of excision.Identification...

Báo cáo y học: " Recent advances in the investigation of curcuminoids" doc

... of anti-HIV-1 integrase. Evidence suggests that curcumin does notbind to HIV-1 integrase at either the DNA-bindingdomain [58] or the binding site of another HIV-1 inte-grase inhibitor, i.e. ... unique linker bridgingtwo catechol rings, showed potency comparable to that of 35 and 36, and greater than that of 2. In the further SAR investigation of curcumin analogs asinhibitors of HIV-1 integrase, ... respectively, and thus, the addition of methyl groups on the phenyl rings enhancedanti-inflammatory activity. The increased size of the cyclo-alkanone ring, by replacing the cyclopentanone in 27 witha...

Báo cáo khoa học: "Lexical Selection in the Process of Language Generation" ppt

... (I) the input for the generation of a sentence includes an instance of an object present in a recent input; and (2) the the previous instance of this object (the po- tential antecedent} is in ... distinguish the following major contributing factors for selecting one verb over the other;, (I) the intended perspec- tive of the situation, (2) the emphasis of one activity rather than another, ... slots in input frames; 4. The history of processing, structured Mong the lines of the episodic memory oWaa~zat~on suggested by Kolodner (1984) and including the feedback of the results of...

Báo cáo y học: "Recent advances in nanoparticle formulation of oleanolic acid" docx

... equallyState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, ChinaChen et al. Chinese Medicine 2011, 6:20http://www.cmjournal.org/content/6/1/20© ... Journal of Xinjiang Medical University 2007, 30:581-583.24. Xiao Y, Song Y, Chen Z, Ping Q: Preparation of silymarin proliposome: anew way to increase oral bioavailability of silymarin in beagle ... polydisper-sity index of 0.242 [19]. The study showed that the opti-mum lyophilized powder could be obtained with 10%sucrose as a cryoprotectant.NanocapsulesLoading of drugs into ultrafine host...

báo cáo khoa học: "Recent advances in gastrointestinal oncology updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology" doc

... of gemcitabine and oxaliplatin alone or in combinationwith biweekly cetuximab in the first-line treatment of advanced biliarycancer: Interim analysis of the BINGO trial. J Clin Oncol (Meeting ... Role of mitomycin in combinationwith fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of ... survival. The investiga-tors noted t hat the incidence of DVT was lower in the treatment arm as compared with the observation arm(10% vs. 1.3%), without any increase in the bleeding risk.However, there...

báo cáo khoa học: " Recent insights into the role of NF-κB in ovarian carcinogenesis" pot

... AB: Recent insights into the role of NF-κB in ovarian carcinogenesis. Genome Medicine 2010, 2:56.Alvero Genome Medicine 2010, 2:56 http://genomemedicine.com/content/2/8/56Page 3 of 3 in the ... pathway.AbbreviationsEOC, epithelial ovarian cancer cells; IKKα, inhibitor of NF-κB kinase α; IKKβ, inhibitor of NF-κB kinase β; IκB, inhibitor of NFκB; IL, interleukin; NF-κB, Nuclear factor kappa-light-chain-enhancer ... IκB is then ubiquitinated and degraded by the proteasome system, leading to the release of p65 and p50. The heterodimer then translocates to the nucleus and initiates the expression of genes...

Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc

... to the complete mineraliza-tion of the pyrrolidine ring of nicotine, which afteroxidation by 6-hydroxy-l-nicotine oxidase, is cleavedoff from the pyridine ring of nicotine in the form of CH3-4-aminobutyrate. ... expression of these genesdepends on the presence of nicotine in the growthmedium and we have determined the enzyme activities of the proteins. Our results demonstrate the presence of two pathways of ... pyrrolidine moiety of nicotine.Expression of the genes of these enzymes was dependent on the presence of nicotine in the growth medium. Thus, two enzymes of the nicotine regulon,c-N-methylaminobutyrate...

Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx

... wild-type protein at 0 h). Nevertheless, itcould also be explained by changes in translation ormaturation of the protein. An increase was alsoobserved in the rate of degradation of the remainingmutant ... of the signaling event. In particular, the rapid degradation of signaling proteins by the protea-some ⁄ ubiquitin system appears to play an importantrole in the control of the duration of the ... after incubation with[35S]methionine may indicate an alteration in the rate of its degradation during the labeling period. In fact,only 15% of 35S-labeled mutant protein remains (vs.100% of...

Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

... suppression of respiration during hypoxia. In the absence of differential regulation of a specific nucleargene coding for the subunits of CytOX, changes in the microenvironment of the cell may induce ... though the catalytic efficiency of the enzyme (TN for cytochrome c oxidase) remainednearly the same. Increased glycolytic flux and alterations in the kinetic characteristics of the CytOX might be the ... shows the effects of hypoxia on the steadystate levels of nuclear genome encoded CytOX IV and VbmRNAs. There was no change in the levels of these mRNAs in macrophages at 6 h of hypoxia, the time...

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