... experiments and types of analysis. Upper panel: in the discovery steps, synovial antigen microarrays and multiplex cytokine assays were employed to determine candidate molecules that are differentially ... single-antigen ELISAs werecombined with the measurements from the bead-arraycytokine assay for integrated analysis of cytokine and autoan-tibody profiles in baseline samples derived from all ... WL and BHT performed the statisti-cal analysis. FB, RFvV, JL, LK, YT, KS, PKG and MCG partici-pated in design and coordination. WH drafted the manuscript.All authors read and approved the final...