Báo cáo y học: "Benign gastro-colic fistula in a woman presenting with weight loss and intermittent vomiting: a case report" pps
Báo cáo y học: "Benign gastro-colic fistula in a woman presenting with weight loss and intermittent vomiting: a case report" pps
... CAS E REP O R T Open AccessBenign gastro-colic fistula in a woman presenting with weight loss and intermittent vomiting: a case reportKate Barrett*, Michael W Hii and Richard J CadeAbstractIntroduction: ... management and prognosis. Case presentation: An 84-year-old woman of Caucasian background presented with 12 months of worseningabdominal pain, nausea, vomiting, diarrhea and weight loss on a background ... vomiting, diarrhea and approxi-mately 20 kilogram weight loss. She denied any hema-temesis, melena or fever. At presentation our patientwas frail and emaciated. Regarding clinical examination,there...
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Báo cáo y học: "Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab" ppt
... same synovia as in (a) and (b). Tissues were obtained by arthroplasty or arthroscopic shaver biopsy, and cDNA was analyzed by quantitative real-time polymerase chain reaction (a, b). Extracts ... arthritis (RA) synovial extracts. Tissues were obtained by arthroplasty or arthroscopic shaver biopsy, and serum and synovial extracts were analyzed by enzyme-linked immunosorbent assay for antibodies ... of interest and albumin. GAPDH-normalized message for IgM (c) and IgG1 (d) heavy constant region as determined by quantitative real-time polymer-ase chain reaction in the same synovia as in...
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Báo cáo y học: "Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations" pptx
... disease duration, with a mean duration of 9.3 years. ATA-positive patients had a mean disease duration of 8.0 years, and ARA-positive patients and Ab-Neg patients had disease durations of 5.4 years ... IFNγ, and TNFα.Together these data demonstrate that circulating cytokine lev-els are different in healthy males and females and are depend-ent on age.Changes in plasma cytokines in scleroderma ... skin and internal organs. Anti-centromere antibodies (ACAs), anti-topoisomerase antibodies(ATAs), and anti-RNA polymerase III antibodies (ARAs) are threemutually exclusive SSc-associated autoantibodies...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... of antioxidants accompanied by raised levels of markers of free radical damage play a major role in delaying wound healing. Ultra-low microcurrent presumably has an antioxidant effect, and ... CR, Carey AL, Hawley JA, Febbraio MA. Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are re-duced in patients with type 2 diabetes: evidence that insulin resistance is associated ... present bilaterally. Popliteal and pedal pulses were absent bilaterally with poor capillary re-fill. The left foot was red and inflamed up to and in- cluding the medial malleolus. The lateral aspect...
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Báo cáo y học: "Endothelial cell phenotypes in the rheumatoid synovium: activated, angiogenic, apoptotic and leaky" pps
... fibronectin, and α6β1 that interacts with laminin. In addition, collagen-binding integrins are expressed by the vascular endothelium,including α2β1. αV can associate with several β chains and can have ... RAendothelial cells and in a variety of other cell types [114].Kinin levels are raised in RA and have been implicated in the pathogenesis of RA by causing release of cytokine and noncytokine ... may increase oedema, and hence joint swelling, in RA. VEGF levels in the sera and synovial fluids of patients with RA are markedly higher than in OA patients ornormal patients [66]. In the RA...
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Báo cáo y học: "Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus" pptx
... psoriasis study analyzed a region previouslyidentified by linkage in sibling pairs, and by thoroughhaplotype analysis narrowed it down to a singlepolymorphism (having excluded the remaining nine ... so far in humans include the RUNX1 proteinpreviously known as AML 1a. AML 1a was originallyidentified because it is frequently involved in mutations and translocations associated with acute myeloid ... rheumatoidarthritis, psoriasis and lupusMarta E Alarcón-RiquelmeDepartment of Genetics and Pathology, Rudbeck Laboratory, University of Uppsala, Uppsala, SwedenCorresponding author: Marta E Alarcón-Riquelme,...
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Báo cáo y học: "Relaxin''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx
... colla-genase-1 and stromelysin-1 [30], and their induction byrelaxin was accompanied by a loss of their matrix sub-strates, collagenase-1 and stromelysin-1 are probablyinvolved in the relaxin-mediated ... were analyzedfor collagen and GAG concentrations. Relaxin and β-estradiolplus relaxin induced the MMPs collagenase-1 and stromelysin-1 in fibrocartilaginous explants – a finding similar to that ... [23-25]. In addition, gelatinzymograms selectively detect proteinase activity at 53/58kDa and at 43 kDa attributable primarily to collagenaserather than stromelysin because gelatin is a poor...
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Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps
... Kira Adaricheva for algorithmic and mathematical support during data analysis. We are indebted to David George and Yonghong Zhang for Affymetrix fluidic station operation and data management. ... Data represent results obtained with RNA from normal paws of naive BALB/cSCID mice (AN), clinically normal pre-arthritic paws (PA), acutely arthritic paws (AA) and chronically inflamed paws ... hybridization and scanning experiments, managed preliminary data analysis and finalized the manuscript. TTG designed experiments,controlled all experimental steps, data analysis, and final-ized...
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Báo cáo y học: "Psychological pain treatment in fibromyalgia syndrome: efficacy of operant behavioural and cognitive behavioural treatments" pptx
... maintenance and exacerbation of symptoms and disability) and thus aims primarily to alter the attitude ofthe patients toward the pain and self-management.Turk and colleagues have demonstrated ... 'Learning, plasticity and pain'), the Max-Planck Award for International Cooperation to HF, and the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and ... time-contingent intake and reduction of medication, increase ofbodily activity, reduction of interference of pain with activities,reduction of pain behaviours, and training in assertive pain-incompatible...
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Báo cáo y học: " Coronary arterial calcification in rheumatoid arthritis: comparison with the Multi-Ethnic Study of Atherosclerosis" pps
... nature of the analysis, and the discrepancymay be the result of random variability. Importantly, a singlemeasurement of inflammatory cytokines is not representativeof the total inflammatory ... mean Agatston calcium scores for participants with any coronary artery calcification (Agatston score > 0)Adjusted mean Agatston calcium scores for participants with any coronary artery calcification ... plaque and rheumatoid synovium share an array of inflammatory cells and cytokines [14], suggesting that chronic rheumatoid inflam-mation may contribute to excess atherosclerosis in RA. In addi-tion,...
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