báo cáo khoa học: " Determinants of the intention of elementary school nurses to adopt a redefined role in health promotion at school" docx

... was to identify the psycho-social determinants of the intention of elementary school nurses (ESNs) to adopt a redefined and expanded role in health promotion in the context of an HPSapproach. ... extra workload rather than a reorganisation of mandates, leaving school nurses with poor feelings of self-efficacy to ac complish health- promotion manda tes[3,14].Attitude was another variable ... youth health. The aim of this study was to identify the determinants of the intention of elementary school nurses to adopt a new health- promotion role as a strategic option for the health- promoting school. Methods:...

Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf

... mitochon-drial respiratory chain, the assistance of speciﬁcchaperone proteins is also required. The available dataindicate that the accessory factor Bcs1p is involved in the binding of ISP to an immature ... seen in the molecular mass of the bc1complex in these two deletion strains, thus leading to the hypothesisthat the addition of ISP may play a pivotal role in the structural rearrangement of the ... [23].However, in the midst of this quickly evolving con-text of macromolecular organization of the mitochon-drial proteome, comparatively little is known about the assembly pathway leading to the maturation...

Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt

... hcHAT2 indicate the eventualintermediary or primordial character of both hcHAT1and hcHAT2 with regard to the appearance of typicalrBAT and typical 4F2hc proteins in animals. Thisseems to ... central TIM barrel domain,including domain B and the C-terminal domain C forrBAT proteins (669 residues on average); (b) the cata-lytic TIM barrel domain, including domain B and the C-terminal ... hypo-thetical hcHAT-like proteins, covering the basal meta-zoans and arthropods that are very probablyhomologues to heavy-chain partners of the light-chainsubunits of the HAT system of chordates,...

Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt

... Most mam-malian PLDs contain a PX and a PH domain instead of the C2 domain in plants, whereas microbial PLDslack such probably regulatory domains.Despite the increasing amount of primary structuraldata ... that the calcium-binding event of lower afﬁnity is attributable to the catalytic site of PLDa2, as found for PLDb from A. thaliana [39]. The decrease in PLD activity at concentrationsabove the ... by small-angle X-ray scattering (SAXS).Further structural information was obtained by the spectroscopic characterization of PLDa2 in the nativestate. The high instability of puriﬁed plant PLDs,...

Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf

... Sendai, Japan3 Department of Biochemistry, Yamagata University School of Medicine, Yamagata, JapanHeme oxygenase (HO) is the rate-limiting enzyme in heme catabolism and cleaves heme to release iron, ... levelYongzhao Zhang1, Kazumichi Furuyama1, Kiriko Kaneko1, Yuanying Ding1, Kazuhiro Ogawa2,*,Miki Yoshizawa1, Masaki Kawamura1, Kazuhisa Takeda1, Tadashi Yoshida3and Shigeki Shibahara11 ... line,and then subjected to northern blot analysis. Each lane contains15 lg of total RNA. The bottom panel shows the expression of b-actin mRNA as an internal control. (B) Western blot analysis. The indicated...

Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate speciﬁcity by replacement of Asn149 with Asp docx

... 4543cally important residues may be adopted by agmatine in E. coli agmatinase and l-arginine in B. caldoveloxarginase [37], indicating that the substrate speciﬁcity of these enzymes rely mainly in ... [22]. A key factor is the a- carboxyl group of the substrate, which makes the difference betweenarginine and agmatine. Agmatine, which results fromdecarboxylation of arginine by arginine decarboxylase,is ... considered for arginase and agmatinase[20]. Such substrate discrimination is particularlyimportant for mammalian arginase II and agmatinase,as both enzymes are mitochondrial and functionallydifferent...

Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot

... provides a measure of the compressional elasticity of a monolayer and can be used to characterize the phase state of the isotherm, thereby providing information about the compactness and packing of the ... membranes, and, on the basis of these combined data, it is suggested that the peptidefunctions as an anionic membrane-interactive a- AMP.These data also suggest that the antimicrobial activity of ... 389–395.43 Sospedra P, Espina M, Gomara MJ, Alsina MA, HaroI & Mestres C (2001) Study at the air ⁄ water interface of a hepatitis A N-acetylated and C-amidated syntheticpeptide (AcVP3 (110–121)-NH2)....

Báo cáo khoa học: Flexible nets The roles of intrinsic disorder in protein interaction networks potx

... Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA2 School of Informatics, Indiana University – Purdue University Indianapolis, IN, USA3 Laboratory ... Kuraoka I, Morita EH, Saijo M, Matsuda T, Mori-kawa K, Shirakawa M & Tanaka K (1996) Identiﬁca-tion of a damaged-DNA binding domain of the XPAprotein. Mutat Res 362, 87–95.111 Ikegami ... number of dehydrons [144]. This wasinterpreted to mean that the rate of increase in interac-tome complexity (i.e., the rate that new connectivitiesare adopted) coincides with the rate of increase...

Báo cáo khoa học: MicroRNAs and the regulation of ﬁbrosis potx

... thereforeappears that although miRNAs predominately represstranslation through binding within the 3¢-UTR of tar-get mRNA, individual miRNAs might also increasemRNA translation and bind regions within the 5¢-UTR.There ... prolif-eration and induce apoptosis through down-regulation of the mitochondrial-associated anti-apoptotic protein,Bcl-2, leading to activation of caspases 3, 8 and 9[35,36]. In contrast to these studies, ... Medicine, Xi’an Jiaotong University, Shaanxi, China2 NIHR Translational Research Facility in Respiratory Medicine Group, School of Translational Medicine, Stopford Building,University of Manchester,...

Báo cáo khoa học: Evidence for the presence of ferritin in plant mitochondria pdf

... (Table 1). ATPaseactivity of this fraction was, indeed, uninhibited or only veryslightly inhibited by vanadate (plasmalemma ATPaseinhibitor), baﬁlomycin A 1(tonoplast ATPase inhibitor)and ... mitochondria(Table 3). The data presented in this paper strongly indicate a mitochondrial localization for ferritins in P. sativum and A. thaliana and could be rationalized as follows: the proteinmay be ... proteins were separated by SDS/PAGE. A protein, withan apparent molecular mass of approximately 25–26 kDa(corresponding to that of ferritin), was cross-reacted with anantibody raised against...

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