Báo cáo y học: "JNK suppression is essential for 17b-Estradiol inhibits prostaglandin E2-Induced uPA and MMP9 expressions and cell migration in human LoVo colon cancer cells" ppsx
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... GGC AGA GAA TAC GTT TAT ACT AA 3ÂC14L 5Â TCT CAG ATT GAC TAC TAC AAC TT 3ÂC15U 5Â CAT GAA AAG CAT TTC AAA AA 3ÂC15L 5Â TAA AAA ACA GTG GTT ACC AA 3ÂC16U 5Â CTA AAG AGT ACA CTA TCC TCA C 3ÂC16L ... amplicationbetweenC7UandC8L.Primersinitalicswereusedinthegenotyping of allele M.C1U5Â GAG AGG AAC TGA ACA GAA CAT TG 3ÂC1L 5Â CAA CTG CGT ATT AGT GAA GAA TG 3ÂC2U 5Â AAT CAA ATT TTA TTA TAA GAC C 3ÂC2L5Â AAT AGC TAA TTA GAG ... TTC CAT GGC TTG ATC 3ÂC19L 5Â ATA CAC ACA AAC TCA CAA GG 3ÂMWU 5Â CAA CAT ATT TTA AAT AAA ATT GAC AAT 3ÂC9LM* 5Â ATA AAA ATG GTA TAC CTC ACT TGT*C 3ÂC9UM1 5Â TAA CAA TGA TTC TCT TTC TTT TAG...
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Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration docx
... environ-ment, HSP60 is quickly imported into the mitochondria under conditions of water restriction. HSP60 may play the role as a molecular chaperone in the mitochondria. The import mechanism of HSP60 into ... in the presence of ATP.We have shown here the import system of mammalian HSP60 into the mitochondria. Mammalian HSP60 is synthesized and localized stably in the cytoplasm, and the protein plays ... concerning the import system of HSP60 into the mitochondria. In normal mammalian tissues, HSP60 is detected bothin the cytoplasm and mitochondria. Newly synthesized HSP60 in the cytoplasm will...
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Báo cáo Y học: Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge pptx
... gills may have a mechanism to bind or concentrate bass hepcidin. In summary, bass hepcidin, a homologue of human hepcidin, was isolated from the gills, demonstrates antibac-terial activity against ... the discovery of a novel AMP, bass hepcidin, isolated from the gills of hybrid striped bass. This is the first member of the hepcidin family isolated andcharacterized from fish. Bass hepcidin was ... homogeneity by twoadditional analytical RP/HPLC purification steps as con-firmed by capillary zone electrophoresis (data not shown).MALDI-TOF MS analysis of both fractions revealed thepresence of an...
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Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx
... of Arg121 on cytotoxicity of a- sarcin (Eur. J. Biochem. 268) 6193 Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a- sarcinManuel Masip, Javier Lacadena*, ... interaction of a- sarcin with phospholipid membranes.It is concluded that Arg121 is a crucial residue for the characteristic cytotoxicity of a- sarcin and presumably of the other fungal ribotoxins.Keywords: ... ribonuclease activity of a- sarcin has been developed by using the dinucleotide ApA as substrate [18]. Both mutant variantshydrolysed ApA. They displayed a Kmvalue similar tothat of the wild-type...
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Báo cáo y học: "Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy" pptx
... Open AccessAdrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapyAlexandra Ahmet1*, Harold Kim2,3 and ... in the diagnosis and management of asthma over the past decade, as wellas the availability of comprehensive and widely-acceptednational and international clinical practice guidelines forthedisease[6,7],asthmacontrolinCanadaremainssuboptimal. ... Spier4Abstract Inhaled corticosteroids (ICSs) are the most effective anti-inflammatory agents available for the treatment of asthma and represent the mainstay of therapy for most patients with the...
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Báo cáo y học: "Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes" ppt
... small-molecule inhibitor of the binding of insulin-like growth factor (IGF) -1 to IGF -binding proteins, on 12 5I-labeled IGF -1 binding to human osteoarthritic chondrocytesEffect of NBI- 317 72, a small-molecule ... articlePharmacological disruption of insulin-like growth factor 1 binding to IGF -binding proteins restores anabolic responses in human osteoarthritic chondrocytesFrédéric De Ceuninck 1 , Audrey Caliez 1 , Laurent ... small-molecule inhibitor of the binding of insulin-like growth factor (IGF) -1 to IGF -binding proteins, on 12 5I-labeled IGF -1 binding to human osteoarthritic chondrocytes. Confluent chondrocytes were incubated...
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Báo cáo y học: "JNK suppression is essential for 17b-Estradiol inhibits prostaglandin E2-Induced uPA and MMP9 expressions and cell migration in human LoVo colon cancer cells" ppsx
... AccessJNK suppression is essential for 17b-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cellsHsi-Hsien Hsu1,2, Wei-Syun Hu3,4, ... 4B). 17b-Estradiol Inhibits PGE2-Induced Cell Migration in Human LoVo Colon Cancer Cells In the present study, w e examined the effects of PGE2on the m igration ability in human LoVo colon cancer cells ... against PGE2-induced progression in colon cancer remains unclear. In the present study, we exam-ined the effects of 17b-estradiol on PGE2-induced cellu-lar motility in human LoVo colon cancer...
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Báo cáo y học: "JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin" ppsx
... purposes)Journal of InflammationOpen AccessResearchJNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittinHye Ji Park1, Hwa ... inhibited by melittin and bee venom. This finding is agreed with otherdata showing that JNK pathway is important signal in the activation of NF-κB in the processes of inflammatory reac-JNK inhibitor ... whethermelittin and bee venom inhibit NF-κB via disrupting MAPkinase signals, and thereby inhibit the inflammatory response in Raw 264.7 macrophages and in the synovio-cytes of rheumatoid arthritis patients.MethodsChemicalsRabbit...
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báo cáo khoa học: " Glutathione synthesis is essential for pollen germination in vitro" ppt
... transcribed in pollen and spermcells. Therefore, we decided to investigate the role of glutathione synthesis for pollen germination in vitro in Arabidopsis thaliana accession Col-0 and in the glutathione ... glutathione depletion in pollen grains triggered disturbances in auxin metabolismwhich led to inhibition of pollen germination. Conclusions: This study demonstrates that glutathione synthesis ... glutathione synthesis is essential for pollen germination in vitro andthat glutathione depletion and auxin metabolism are linked in pollen germination and early elongation of the pollen tube, as IAA...
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báo cáo khoa học: " Ornithine-δ-aminotransferase is essential for Arginine Catabolism but not for Proline Biosynthesis" ppsx
... 14(page number not for citation purposes)BMC Plant BiologyOpen AccessResearch article Ornithine-δ-aminotransferase is essential for Arginine Catabolism but not for Proline BiosynthesisDietmar ... subcellularlocalisation.Ornithine-δ-aminotransferase does not contribute to stress-induced proline accumulationThe mitochondrial localisation of δOAT indicated that it is not involved in the formation ... enzymeconverting Orn to pyrroline-5-carboxylate (P5C), is localised in mitochondria and is essential for Arg catabolism. Wildtype plants could readily catabolise supplied Arg and Orn and were able touse...
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Báo cáo y học: " JNK activation is responsible for mucus overproduction in smoke inhalation injury" potx
... regulating mucus overproduction in smoke inhalation injury. In the present study, MUC5AC protein expression wasincreased within 4 hour after 15 min smoke inhalation. The expression was sustained ... and also in a combined burn and smoke inhalation injury model [6] , but the mechanism bywhich smoke damages the airway still remains unclear. In our mouse model of smoke inhalation injury, wefound ... inhalation duringfiresisassociatedwith mucus hypersec retion, we evaluated mucin secretion i ntheairwayofmicebyusingthePASstain.ThePASstain is mainly used for stai ning str uctures containing ahigh...
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Báo cáo y học: "Endogenous laminin is required for human airway smooth muscle cell maturation" pot
... prolifera-tion of human airway smooth muscle. Am J Physiol Lung Cell MolPhysiol 2006.26. Frid MG, Moiseeva EP, Stenmark KR: Multiple phenotypically dis-tinct smooth muscle cell populations exist in the ... E:Distribution of phenotypically disparate myocyte subpopula-tions in airway smooth muscle. Can J Physiol Pharmacol 2005,83:104-116.34. Halayko AJ, Rector E, Stephens NL: Airway smooth muscle ... mitogenic for human airway smooth muscle. Am JRespir Crit Care Med 1999, 160:2062-2066.31. Rahman MS, Yang J, Shan LY, Unruh H, Yang X, Halayko AJ, GounniAS: IL-17R activation of human airway smooth...
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Báo cáo y học: "b-TrCP is dispensable for Vpu’s ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release" pot
... Retrovirology 2011, 8:9http://www.retrovirology.com/content/8/1/9Page 8 of 15 RESEARCH Open Accessb-TrCP is dispensable for Vpu’s ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 releaseHanna-Mari ... bars), even thoughthey displayed slightly increased steady-state levels rela-tive to Vpu wt due to their higher stability [29]. Parallelanalysis for expression of CD4 revealed the expected[19] ... Infectious HIV-1 ( % Control)101100 HIV-1 wt HIV-1 YSXsi Controlsi ȕ7U&3si ȕ7U&3 HIV-1 YSX HIV-1 wtsi ȕ7U&3 si ȕ7U&3si Control HIV-1 YSX HIV-1 wt HIV-1 YSX HIV-1 wtB HIV-1 YSXHIV-1...
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Báo cáo y học: "Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells" doc
... proteins that can bind p53 might inhibit itspro-apoptotic activity, allowing more cells to becomeeither productively or latently infected with HIV-1 [52]. Itcan be postulated that the type-I ... relativelyhigh number of genes we found to be regulated by HIV-1 in the microarray experiment that interact with p53 eitherdirectly or indirectly, such as HIV-1 Tat interacting protein(HTATIP2), ... ofTP53BP2 in regard to HIV-1 and its relation with p53 in the near future.An elegant study has documented a mechanism involved in transcriptional regulation of p53 that is mediated bytype-I...
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Báo cáo y học: "Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep" pdf
... that occur during the initiation and progression of chronic leukemia such as ATL and B-CLL in human. In the model of BLV-induced leukemia and lymphoid tumors, viral infection and tumor progression ... is linked with the onset of acute leukemia. We propose that in this particular case, the mechanism by which the immune system destroys developing malignancies is evaded by the malignant cell by reducing ... is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheepMakram Merimi1, Pavel Klener1,2, Maud Szynal1, Yvette Cleuter1,...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Chuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ