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Báo cáo y học: "Ethnoveterinary treatments by dromedary camel herders in the Suleiman Mountainous Region in Pakistan: an observation and questionnaire study" ppt

Báo cáo Y học: Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe pdf

Báo cáo Y học: Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe pdf

... Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe Teresa Soto, Alejandro Franco, ... for the participation of the cata-bolic enzyme trehalase in the structural framework of aregulatory macromolecular complex containing trehalose- 6-P synthase in the fission yeast. Keywords: neutral ... respectively.DISCUSSIONTwo main lines of evidence lead us to propose that in the fission yeast S. pombe neutral trehalase (Ntp1p) interacts in vitro with other proteins involved in trehalose metabo-lism. First, the activation...
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Báo cáo y học: "Self-rated health showed a consistent association with serum HDL-cholesterol in the cross-sectional Oslo Health Study" pptx

... activity, whilst, on the other hand, physical activity may promote good health. In any instance, also in the present study there was a consistent positive association between physical activity and ... illnesses only partially explains the association between HDL-C and SRH. Time since food intake The fact that the blood samples were not obtained in the fasting state is a limitation in the present ... regards adaptation to the Norwegian way of living, in adjusting their traditional dietary habits, and possibly difficulties in correctly interpreting the question about health. Additionally, some...
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Báo cáo y học: "Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease" ppsx

... [ 42] but also as co-stimulators of cells of the adaptive immune system. TLR -2 engagement therefore influences the differentiation of T cells not only by the activation of DCs (indirect pathwayFigure ... Toll-like receptor (TLR) -2 on pre-activated T cells in pathogen-induced chronic inflammatory joint diseasesExplanation for the involvement of Toll-like receptor (TLR) -2 on pre-activated T cells in pathogen-induced ... the T cell receptor. T/ TEinflamed joint activated andmemory T cells can passendothelial barriersTLR ligandscan activate T cells independent of antigenic specificityrelease of inflammatory...
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Báo cáo y học: "Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians" potx

... gene as a susceptibilityfactor for osteoarthritis (OA). Alleles of this microsatellitedetermine the variable number of aspartic acid residues in the amino-terminal end of the asporin protein. ... in normal cartilage but that is notably increased in OA cartilage[4]. Variant ASPN proteins are due to a microsatellite in the ASPN coding sequence that determines a variable number of aspartic acid ... The OA-associated allele, with 14 aspartic acid residues, inhibits the anabolic effects of transforming growth factor beta more strongly than other asporin alleles, leading to increased OA liability....
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Báo cáo y học: "Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus" potx

... articleEffect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosusMichael Mahler1, Aderajew Waka2, F Hiepe3 and Marvin J Fritzler41Development ... which may result in the detection of anti- dsDNA antibodies in the SmD peptide ELISA [32]. In the present study we confirmed the dsDNA binding property of the SmD1 peptide. This finding was further ... from the second serum panelFigure 2 Binding of SmD peptides to dsDNABinding of SmD peptides to dsDNA. (a) SmD1, SmD3 and biotinylated control peptides (PM1-α and Ribosomal P) were serially diluted...
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Báo cáo y học: "Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice" doc

... articleMagnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in miceNicoleta Butoescu1, ChristianASeemayer2, Gaby Palmer3,4, ... tomography scanAll animals implanted with a magnet and used either for the in vivo imaging experiment or for the efficacy testing in the AIA model were imaged by micro-CT scan in order to assess the magnet ... of microparticles containing DXM and SPIONs (referred to ascomplete microparticles) as an anti-inflammatory drug delivery system in an experimental model of antigen-induced arthritis (AIA) in...
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Báo cáo y học: "Ethnoveterinary treatments by dromedary camel herders in the Suleiman Mountainous Region in Pakistan: an observation and questionnaire study" ppt

... reproduction in any medium, provided the original work is properly cited.ResearchEthnoveterinary treatments by dromedary camel herders in the Suleiman Mountainous Region in Pakistan: an observation and ... Ethnoveterinary treatments by dromedary camel herders in the Suleiman Mountainous Region in Pakistan: an observa-tion and questionnaire study Journal of Ethnobiology and Ethnomedicine 2010, 6:16 Raziq ... summer is warm (mean 21-32°C) and in the winter the temperature drops below 0°C. Rain (and occasionally snow) falls predominantly in the spring and the monsoon. Vegetation is sparse and consists of...
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Báo cáo y học: "Intra-operative intravenous fluid restriction reduces perioperative red blood cell transfusion in elective cardiac surgery, especially in transfusion-prone patients: a prospective, randomized controlled trial" ppsx

... perioperative red blood cell transfusion in elective cardiac surgery, especially in transfusion- prone patients: a prospective, randomized controlled trialGeorge Vretzakis1, Athina Kleitsaki1, Konstantinos ... red blood cell transfusion in elective cardiac surgery, especially in transfusion- prone patients: a prospective, randomized controlled trial. Journal of Cardiothoracic Surgery 2010 5:7.Submit your ... of patients, and had adequate power for investi-gating the impact of perioperative intravenous fluid restriction on red blood cell transfusions not only in cardiac surgery patients in general,...
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Báo cáo y học: "Progression of metastatic castrate-resistant prostate cancer: impact of therapeutic intervention in the post-docetaxel space" pps

... efficacy findings of the trial (Table 1) prompt ed the Independent Data Monitoring Committee to recom-mend unblinding the trial at the time of the interim analy-sis and the crossover of patients ... growth to prostate cancer cells.Interestingly, however, in mo del systems they may beinhibited by antiandrogens targeted to the ligand-bindingdomain, such as MDV3100 (see below) [20]. Hypotheti-cally ... pathwaysmayplayaroleintheemergenceofCRPC.Theinterac-tion of endothelin-1 (ET-1) with the G-protein coupledendothelin-A (ETA) receptor has been implicated in car-cinogenesis, and results in the triggering of several intra-cellular...
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Báo cáo y học: "Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-B-dependent transcription of TNF-a and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA" ppsx

... AccessTetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-B-dependent transcription of TNF-a and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNAAkinbolade O Oyegunwa, ... play a key role in the transcriptionalactivation of cytokine genes after LPS stimulation [25].Ther efore, we hypothesize d, that the inhibitory effects of TMP on the transcription of TNF-a and ... inhibitoryeffect of TMP on the interaction between RelA and its cognate sites on the DNA. TMP could be acting on RelA itself, binding to conserved motifs present in the amino terminus RHD thereby preven...
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Báo cáo y học: " Bilateral thalamic stroke due to occlusion of the artery of Percheron in a patient with patent foramen ovale: a case report" pot

... pathophysiology of bila teral paramedian thalamic infarction. Paramedian nuclei consist mainly of a dorsomedian nucleus and intralaminar nuclei. The intralaminar nuclei consist of parafascicular, ... http://jmedicalcasereports.com/jmedicalcasereports/article/view/7392 Case reportOpen Access Bilateral thalamic stroke due to occlusion of the artery of Percheron in a patient with patent foramen ovale: ... 9]. The thalamic arterial supply arises from perforating vessels with a complex distribution [10]. The paramedian thalamic territory is the median part of the thalamusincluding the intralami nar...
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Báo cáo y học: " High-risk HPV E5-induced cell fusion: a critical initiating event in the early stage of HPV-associated cervical cancer" pptx

... wehypothesize that high-risk HPV E5-induced cell fusion is a critical event in the early stage of HPV- associated cer-vical cancer.Presentation of the hypothesis The fact that aneuploid cells are ... virus-induced cell fusion can initiatecancer is an appealing mechanism. In this article, wepropo se that high-risk HPV E5-induced cell fusion is animportant event in the early stage of HPV- associated cervical ... on the observations mentioned above, we pro-pose that high-risk HPV E5-induced cell fusion mayplay a critical role in the early stage of HPV- associated cervical cance r. However, it is widely...
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Báo cáo y học: "Infectious salmon anaemia virus (ISAV) isolated from the ISA disease outbreaks in Chile diverged from ISAV isolates from Norway around 1996 and was disseminated around 2005, based on surface glycoprotein gene sequences" pptx

... citation purposes)Virology JournalOpen AccessResearchInfectious salmon anaemia virus (ISAV) isolated from the ISA disease outbreaks in Chile diverged from ISAV isolates from Norway around 1996 ... estimated the Chile isolates diverged from Norway isolates around 1996, and follow-ing a recombination event (insertion event) in the F gene around 2005, were quickly disseminated throughout the Atlantic ... protein. The amino acid sequence corresponding to the fusion protein of the Chilean ISAV in this disease outbreak is highlighted in yel-low. The designation of amino acid inserts IN1 , IN2 , and IN3 ...
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Báo cáo y học: "Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study" docx

... light sedation) in accordance with the COMFORT classification.Data are expressed as mean ± standard deviation in the case of a normal distribution and interval scaling level, and asmedian (range) ... monitoring sedation in paediatric intensive care unit (PICU) patients.Methods Forty paediatric patients (<18 years) were sedated for mechanical ventilation in a cardiacsurgical and general ... bispectral index; EEG = electroencephalography; ICU = intensive care unit; PICU = paediatric intensive care unit; ROC = receiver operating characteristic; RSS = Ramsay Sedation Score. Available...
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