... anion, hydrogen peroxide (H2O2), and hydroxyl rad-ical (OHS), with the potential to initiate cellular damage in joint tissues especially in RA. They are formed by phagocyte activation during inflammation. ... Fethi Ceylan3 1. Yuzuncu Yil University, Medical Faculty, Department of Physical Medicine Rehabilitation and Rheumatology, Van, Turkey; 2. Yuzuncu Yil University, Medical Faculty, Department ... inflam-matory, autoimmune, systemic disease, in which various joints in the body are inflamed, leading to swelling, pain, stiffness, and the possible loss of func-tion. Pathologically, synovial...