... antibodies, ANAs,immunoglobulins (IgG, IgM, IgE, and IgA), and complement(C3 and C4). Anti-dsDNA antibodies and ANAs were meas-ured by Farr assay (Specialty Laboratories, Santa Monica, CA,USA) and indirect ... BLyS isenzymatically cleaved from the cell membrane and can bind toany of three receptors: TACI (transmembrane activator and calcium-modulator and cyclophilin ligand interactor) [7];BCMA (B-cell ... demonstrated itssafety, biologic activity, and pharmacokinetics.Materials and methodsPatientsPatients aged 18 years or older with SLE, as defined by theAmerican College of Rheumatology criteria...