Báo cáo y học: "Increased levels of circulating microparticles in primary Sjögren''''''''s syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity" pdf
Báo cáo y học: "Increased levels of circulating microparticles in primary Sjögren''''s syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity" pdf
... plasma levels of total, platelet and leukocyte MPs by prothrombinase capture assay and flowcytometry in 43 patients with pSS, 20 with SLE and 24 with RA and in 44 healthy controls (HCs). Secretory ... and activity in someinflammatory diseases and catalyzes hydrolysis of aminophos-pholipids, including PS, as well as phosphatidylcholine and phsophatidylethanolamine, all contained in microvesicles ... sCD62P in patients with primary Sjögren syndrome (pSS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and in healthy controls (HCs)pSS SLE RA HCMP level by capture assay, nM...
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Báo cáo y học: " Epratuzumab (humanised anti-CD22 antibody) in primary Sjögren''''s syndrome: an open-label phase I/II study" docx
... improvement in subjective and objective measures, including subjectivereports of dryness, fatigue, and salivary flow, mainly in patients with early-onset disease and in only a few with pSS-associ-ated ... times duringtheir clinical course (with a mean inter-visit interval of 123 days and range of 13–638 days) and a mean duration of the survey of 492 days (range 13–1,022 days), we observed an inter-contact ... pre- and post-therapybiopsies of minor salivary glands. Additional findings in terms of statistically significant improvement from baseline in fatigue, and in patient and physician global assessments...
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Báo cáo y học: "The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis" ppsx
... [87,88].Outbred strains have high-density recombinations that canallow mapping to subcentimorgan levels in one generation, bycombining the advantages of association mapping with thepower of mapping in animal ... moreefficient by minimizing the cost of genotyping. By creating1,000 recombinant inbred lines from eight founder strainsthat are first intercrossed to mix the genomes and theninbred, a permanent ... binding groove, and changingthese to the corresponding amino acids in the H2qsequencemakes the H2pmice susceptible to CIA [70]. Interestingly,the binding groove of the H2qMHC strongly...
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Báo cáo y học: "Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study" pps
... osteophytes and definite joint space narrowing. bScoring was as follows: +/-, minimum staining in one area of the tissue; +, patchy staining involving several areas; ++, moderate diffuse staining. ... taking a variety of medications, including non-steroi-dal anti-inflammatory drugs, external splints and intra-artic-ular injections of prednisone and/ or hyaluronic acid.Intra-articular injection ... associated symptoms closely resemble those of rheumatoid arthritis (RA). The histopathological changes in HAAP include marked proliferation of synoviocytes in thesynovial lining layer, gross infiltration...
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Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot
... Pers and colleagues [15] and Figure 2 Relation between cytokine levels and B-cell frequencyRelation between cytokine levels and B-cell frequency. (a) Two patients with systemic lupus erythematosus ... production of B lym-phocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum 2003,48:982-992.30. Ronnblom L, Alm GV: Systemic lupus erythematosus ... circu-lating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus. Ann RheumDis 2004, 63:1096-1103.28. Koyama T, Tsukamoto H, Miyagi Y, Himeji...
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Báo cáo y học: "Anti-cyclic citrullinated peptide antibodies in primary Sjögren syndrome may be associated with non-erosive synovitis" ppt
... conception of the study and the acquisition, analysis, and interpretation of data and partic-ipated in drafting the manuscript. NL participated in the analy-sis and interpretation of data. EB and ... anti-bodies in patients with mixed connective tissue disease (MCTD) (9%), systemic lupus erythematosus (14%), systemic sclerosis (13%), polymyositis/dermatomyositis (14%), and SSTable 3Correlations with ... as fatigue, myalgia,arthralgia, an intermittent non-erosive polyarthropathy affect-ing mainly the small joints, and usually mild synovitis are com-mon in patients with pSS and may mimic RA,...
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Báo cáo y học: "The usefulness of circulating adipokine levels for the assessment of obesity-related health problems" pptx
... al. Circulating retinol- binding protein-4, insulin sensitivity, insulin secretion, and insulin dis-position index in obese and nonobese subjects. Diabetes Care 2007; 30: 1802-6. 176. Yagmur ... me-diates the infiltration of macrophages into WAT in obesity and may play an important role in establishing and maintaining a proinflammatory state that predis-poses to the development of IR and MS ... family history of premature coronary artery disease Correlation with the levels of inflammatory markers Reilly et al., (2005) [90] Japanese subjects Associated with the presence and severity of...
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Báo cáo y học: "Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus" ppsx
... chemotactic and inflammatory potential of theactivated monocytes may participate in a vicious cycle of immune cell recruitment and renal injury in SLE.Introduction Systemic lupus erythematosus ... 1Expression of Fc receptors in healthy control individuals versus systemic lupus erythematosus patientsExpression of Fc receptors in healthy control individuals versus systemic lupus erythematosus ... MaillotMC, Durand-Gasselin I, Fourrier BM, Galanaud P, Emilie D: Spon-taneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus. Eur CytokineNetw 1993,...
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Báo cáo y học: "Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus" pdf
... chemotactic and inflammatory potential of theactivated monocytes may participate in a vicious cycle of immune cell recruitment and renal injury in SLE.Introduction Systemic lupus erythematosus ... per-haps including serum levels of the cytokines examined in our in vitro studies, will require further study.FcγRI/CD64 plays a role in phagocytosis, cytolysis, degranu-lation, and induction of inflammatory ... MaillotMC, Durand-Gasselin I, Fourrier BM, Galanaud P, Emilie D: Spon-taneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus. Eur CytokineNetw 1993,...
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báo cáo hóa học: " Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures" pot
... elucidated. Cytokines may contribute initi-ally to incite seizures in the developing brain after beinginduced by seizure or tissue injury, and they may exacer-bate tissue injury and promote ... serumHMGB1 levels are elevated in patients with infection and/ or systemic inflammatory response syndrome, than in healthy control individuals [19,21]. H MGB1 isinvolved in various diseases without ... the levels of IL-1 are low, both in the circulation and in the CNS, whereas upon infectionor injury, IL-1 levels increase abruptly but transiently,returning to normal within 8 h in healthy, young...
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