... by Pers and colleagues [15] andFigure 2Relation between cytokine levels and B-cell frequencyRelation between cytokine levels and B-cell frequency. (a) Two patients with systemic lupus erythematosus ... patients with systemic lupus erythema-tosus: longitudinal observations. Arthritis Rheum 2003,48:3475-3486.13. Seyler TM, Park YW, Takemura S, Bram RJ, Kurtin PJ, Goronzy JJ,Weyand CM: BLyS ... frequencies in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) treated with the B-cell-depleting agent rituximab. Ten patients with SLE weretreated with rituximab...