... Central to the success of such initiatives has been an increased appreciation ofthe role of human factors, the value of teamwork and the principles of reliable system design Specifically they have ... contributions to the interpretation ofthe data and drafted the earlier versions ofthe manuscript BP made substantial contributions to the acquisition and analysis ofthe data and drafted the earlier ... and the simple effect of knowing they are to be asked significantly improve the reliability ofthe clinical processes and may reduce complications by up to 50% [11] The NPSA has instituted the...
... Central to the success of such initiatives has been an increased appreciation ofthe role of human factors, the value of teamwork and the principles of reliable system design Specifically they have ... contributions to the interpretation ofthe data and drafted the earlier versions ofthe manuscript BP made substantial contributions to the acquisition and analysis ofthe data and drafted the earlier ... and the simple effect of knowing they are to be asked significantly improve the reliability ofthe clinical processes and may reduce complications by up to 50% [11] The NPSA has instituted the...
... adverse effects of anti-malarial drug therapy in SLE concludes that hydroxychloroquine should be given to most patients with SLE during the whole course ofthe disease, irrespective of severity, ... preserving the processing of high affinity antigens (for example, foreign peptides) [6] The benefits of anti-malarials in patients with SLE go beyond preventing infection and include prevention of disease ... autoimmunity through inhibition of toll-like receptors and The anti-malarials are immunomodulatory without being immunosuppressive in that they downregulate the processing of low affinity antigens (for...
... technically futile Under the current rules, the only test of futility is that embodied by the question, ‘Will this treatment result in sustained life?’ If the answer is ‘yes’, then virtually any treatment ... interests The author(s) declare that they have no competing interests References 10 11 12 13 14 Perhaps the most effective way of dealing with strong familial incentives to tread the path of least ... coworkers [15] termed, the large riskof unacceptable badness’, rather than a vanishingly small potential for benefit 318 There are far worse things than death, and many of them occur in ICUs when futility...
... previously that G/G ofthe PTPN11 gene encoding SHP-2 increased theriskof gastric atrophy among the seropositive subjects [18] The present study examined the association of a polymorphism of Gab1 with ... eradication ofthe bacteria However, the OR ofthe A/A genotype for H pylori seropositivity was 0.25 (95% CI 0.09-0.71) So, the Gab1 polymorphism was associated with the low riskofthe infection ... diagnosis of cancer In summary, the Gab1 A/A was associated with the low riskof H pylori infection while the G/A and A/A genotypes together may increase therisk for gastric atrophy The biological...
... in the association of unprocessed total meat intake and type DM risk depending on the BMI ofthe women A higher consumption of total unprocessed meat was related to a modest reduction in therisk ... decrease in riskof type DM in the NHS II [6] No association between poultry consumption and riskof type DM was found in the Health Professionals Follow-Up Study [7], the WHS [3], or the NHS I ... To our knowledge there are no other reports of a direct link between poultry consumption and riskof diabetes or of interactions between poultry consumption and BMI and theriskof type DM Red...
... IRA custodians often list the value ofthe investment as the original purchase price, the original purchase price plus returns reported by the promoter, or a price provided by the promoter Investors ... degree of risk, and the level ofrisk typically correlates with the return an investor can expect to receive Low risk generally means low yields, and high yields typically involve higher risk Fraud ... registered, then check out the answers with an unbiased source, such as the SEC or your state securities regulator The SEC has a short publication called “Ask Questions” that discusses many ofthe other...
... into the complicated origins of breast cancer I) THE COCKTAIL EFFECT Despite the theory ofthe role of oestrogen mimicking chemicals in breast cancer, it will be almost impossible to prove the ... theof cial views ofthe funders and the EU institutions Factors influencing theriskof breast cancer – established and emerging April 2008 Introduction Most of us will know of someone affected ... 27) the possession of certain so-called ‘breast cancer genes’2 These are known as ‘established risk factors’ However, all the established risk factors together can only explain about half of breast...
... categorized the TB lesion of each subject as minimal, moderately advanced, or far-advanced, based on the classification ofthe National Tuberculosis and Respiratory Disease Association ofthe USA ... lung is lower than that of patients with COPD (17) Airflow impairment is related to the radiological extent of TB (3) and to the number of TB episodes However, most of these studies had small ... prospectively collected in 2001 by the Korea Institute for Health and Social Affairs Based on the 2000 Population Census ofthe National Statistical Office of Korea, a stratified, multi-stage,...
... accomplish by the year 2020: • People will know how to reduce their riskof cancer Three-quarters ofthe UK public will be aware ofthe main lifestyle choices they can make to reduce their riskof getting ... thousands of new cases ofthe disease, both in the UK and across the world Cancer Research UK has been at the heart of this progress thanks to the sustained support and generosity ofthe UK public The ... whose breast cancer has extra copies ofthe Her-2 gene We have shown that radiotherapy to the breast can reducethe chances of regrowth ofthe tumour after the primary is removed, and that giving...
... in the amount of work they could perform, irrespective of whether they are limited in the kind of work they can perform (1 = yes, and = no) The vast majority of respondents who noted that they ... by the end ofthe study but were at riskof divorce until the study ended) The model I estimated is ofthe following general form and takes into account the fact that all eligible members of ... a result ofthe reduced health of husbands is a testament to the continued gendered nature of marriages The results also speak to the importance of education in determining the nature of negotiations...
... or tamoxifen reduces a woman’s riskof some kinds of breast cancer Some women who take these medicines will still get breast cancer Taking the medicines does not reducetheriskof dying from ... others Talk with your doctor or nurse about your riskof breast cancer Tamoxifen and raloxifene can lower theriskof getting some kinds of breast cancer These medicines also can raise therisk ... years They often can cause hot flashes n Does the cost ofthe medicines affect my decision? The cost ofthe medicines may be important to you They need to be taken for a long time, and the cost...
... Figure the sagittal diameter the corresponding spinal laminar line Theposterior point ofof the spinal canal (a) is measured from The sagittal diameter ofthe spinal canal (a) is measured from the ... sagittal scan ofthe MRI (Figure 2) The level of compression and the multiplicity of compression were also evaluated The presence and location of high-signal intensity area (HIA) in the spinal cord ... posterior point ofthe corresponding spinal laminar line The sagittal diameter ofthe vertebral body (b) is measured at the midpoint, from the anterior surface to the posterior surface The spinal...
... the study and the editing ofthe article BR contributed to shaping ofthe article and the editing ofthe article GEE contributed to the statistical analyses and the editing ofthe manuscripts ... last year Ofthe total sample of patients, 25% (n = 32) had a clinical diagnosis of either LQTS or HCM as opposed to 75% (n = 94) at genetic risk because of family history of LQTS or HCM The socio-demographic ... the strength of relationship between a given predictor, and an outcome in the units of measurement ofthe predictor It is the change in the outcome associated with a unit change in the predictor,...
... indicate their appreciation ofthe value ofthe technology that they have been provided with by the project They have indicated to us that they will use the system on an even greater scale in the ... particular circumstances They must also be aware ofthe impact of their actions on the environment, so as to minimise pollution, and maintain the safety of their co-workers and themselves This means ... proportion of women The activities ofthe Vietnamese collaborators have, therefore, more than compensated for the negative effects ofthe budgetary problems stemming from the exchange rate problems The...
... multiplying the frequency of consumption of each food by the nutrient content ofthe portion and then adding these products across all food items All foodcomposition values were obtained from the Harvard ... intake) to 30 (the highest protein and fat intake and the lowest carbohydrate intake) Therefore, the higher the score, the more closely the participant’s diet followed the pattern of a low-carbohydrate ... percentage of energy as animal protein, and the percentage of energy as animal fat, and the other was calculated according to the percentage of energy as carbohydrate, the percentage of energy...
... Nevertheless, our findings support the theory that the level of C-reactive protein provides an additional measure oftheriskof coronary heart disease beyond that afforded by the Framingham risk ... supports the hypothesis that the levels of C-reactive protein may predict risk beyond the information afforded by lipid levels However, despite the independent associations, the gradient ofrisk ... association between the levels of soluble TNF-a receptors and theriskof coronary heart disease (Table 3) Men in the highest quintile of interleukin-6 had a 57 percent increase in theriskof coronary...
... through the end ofthe year The mean cumulative days of hospitalization at the end of each ofthe 12 months post initiation indicated that the average number of hospitalization days for the RIS-treated ... initiation ofthe drug therapy are assigned to that therapy, even if therapy is discontinued [17] In contrast, the inclusion of patients who were continuously treated with the index drug during the ... times that ofthe olanzapine treatment group By the end ofthe sixth month following initiation, the patients in the RIS-treatment group had a mean of 3.9 hospitalization days more than the OLZ...
... treatable) increase in fracture risk Furthermore, the degree ofrisk or nonrisk in a particular patient cannot be accurately estimated from any combination ofthe identifiable risk factors for osteoporosis ... to control for the effects of age, sex, years of estrogen use, physical activity, the current daily dose of prednisone, years of prednisone use, and the cumulative lifetime dose of inhaled corticosteroid ... already at risk because of established glucocorticoid-induced osteoporosis, bisphosphonates have the capacity to restore bone mass and thus reducetheriskof vertebral fracture.3 They are currently...
... Position the needle tip at the very bottom ofthe solution in the vial stopper when drawing the solution into the syringe Before removing the needle from the vial, pull the plunger all the way ... omalizumab therapy should be informed of both the potential benefits ofthe medication and also ofthe possibility of rare adverse events In particular, patients should receive counseling about the ... occur in these patients, as has been reported in the literature [24], it is more likely that the reaction is due to the immunotherapy rather than the omalizumab Finally, there is also the possibility...