... purposes)endothelial cells induced by mechanical stimulation maylead to the modulation of the activation of neutrophils and macrophages in the lung via proinflammatory cytokines[14] and arachidonic ... impairment of oxygenation. HFO mayreduce lung injury via the attenuation of pulmonary inflammation.Keywords: adhesion molecule, high frequency oscillatory ventilation, leukocyte, lung injury, mechanical ... attenuates the activation of alveolar macrophages and neutrophils in lung injuryMotomu Shimaoku1, Yuji Fujino1, Nobuyuki Taenaka1, Takachika Hiroi2, Hiroshi Kiyono2 and Ikuto Yoshiya11Intensive...