Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx
Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx
... properties byinhibiting the 5-lipoxygenase enzyme. A 90-day, double- blind, randomized, placebo- controlled study was conducted toevaluate the efficacy and safety of 5-Loxin® in the treatment of osteoarthritis ... not for citation purposes)Vol 10 No 4Research articleA double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the ... inserum and haematological parameters, and urine analysis wereperformed to evaluate the safety of 5-Loxin® in OA patients.Results Seventy patients completed the study. At the end of the study, ...
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Báo cáo Y học: A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii potx
... the isolation of the gene locus, full-length cDNA and the functional analysis of the corresponding protein of T. gondii that displays strong similarities with the P. falci-parum, P. yoelii and ... tachyzoites. The tachyzoites differentiate intoencysted bradyzoites in response to the immune systemattack during disease progression. They will remain in the brain and other organs during the ... of infected hosts. The reactivation of encysted bradyzoites into activelyreplicating and cytolytic tachyzoites can trigger a diseasewith severe clinical syndromes leading in many cases to the death...
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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... Raychaudhuri SP. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee. Arthritis Res. Ther. 2008; 10(4): ... in the present clinical study we sought to evaluate the comparative efficacy and tolerability of 5-L o xin® and Aflapin® in the treatment of OA of the knee. Materials and Methods Study ... presently available in the market. A 90-d a y , double- blind, randomized, placebo- controlled study was conducted to evaluate the com-parative efficacy and tolerability of 5-Loxin® and Aflapin®...
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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
... under any conditions and attempts to purify the kinase by gel elution gave a very lowyield and the eluted protein was highly labile. The 40-kDa protein is phosphorylated by PsCCaMK and binds ... pathway, these secondmessengers and/ or other accessory protein(s) affected bythem modulate the activity of the transcription factors,which regulate the expression of specific gene(s) leading to the ... Engineering and Biotechnology and funds from Department of Science and Technology, Government of India. We thank Prof. S. Assmann for critical reading of the manuscript and constructive suggestions and...
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Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx
... randomized, double- blind, placebo- controlled, study of the efficacy and safety of aripiprazole 10, 15 or 20 mg/day for the treatment of patients withacute exacerbations of schizophrenia. J Psychiatr ... than the prestudy medication. Safety and tolerability Of the 245 subjects who were included in the safety sample, 163 (66.5%) experienced an AE during the switching treatment phase and, of the ... 6 of 9Background Randomized, placebo- controlled studies using strictinclusion and exclusion criteria are essent ial when eval-uating the efficacy and safety of a new treatment; how-ever, they...
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Báo cáo y học: "A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia" pps
... significantly improved by tropisetron trial.Conclusions: This first randomised, double- blind, placebo- controlled trial supports the safety and efficacy of adjunctive tropisetron for treatment of cognitive ... by the Department of Pharmacy of Chiba University Hospital.Clinical variables and cognition The Positive and Negative Syndrome Scale (PANSS) wasused to quantify the severity of psychotic symptoms ... would increase the inhibitory synaptic input to pyramidal neurons and thereby diminish the responsiveness of these pyramidalneurons to sensory stimulation [49]. This parallels a study of postmortem...
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Báo cáo y học: "A Randomized Study of Epithelial Ovarian Cancer: Is Chemotherapy Useful after Complete Remission"
... at the Division of Radiotherapy and Medical Oncology, Ospedale Civile in Pordenone, for 6 years and at the Division of Medical Oncology, Centro di Riferimento Oncologico, in Aviano, for 13 years. ... mg/m2 for 5 days followed by Cisplatin at 100 mg/m2 on the 6th or 7th day every 28 days; the other 61 received no further treatment (nihil group). Results. Sixty patients in the Cisplatin ... were proposed for the study and randomly assigned to consolidation chemotherapy with 5-Fluorouracil + Cisplatin or nihil. Inclusion in the study was based on a histologically documented diagnosis,...
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Báo cáo y học: "β A randomized, controlled trial of interferon-β-1a (Avonex®) in patients with rheumatoid arthritis: a pilot study [ISRCTN03626626]" pptx
... phase II randomized, double- blind, placebo- controlled trial of 30 µg IFN-β-1a by weekly self-injection for 24 weeks. The primary outcome of the study was safety. Secondary outcomes included the proportion ... information. The primary outcome of the study was safety. IFN-β-1awas generally well tolerated by these RA patients. We didnot see any serious safety problems with the study drug and no serious ... majority of patients who did not complete the 24-week study terminated because of perceived lack of efficacy rather than because of adverse events. Irrespec-tive of the study s power, the efficacy...
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Báo cáo y học: "A blind deconvolution approach to high-resolution mapping of transcription factor binding sites from ChIP-seq data" pps
... compute the average FWHM and amplitude for the region by taking the mean of the forward and reverse val-ues.We then take the top quartile of the enriched regionsaccording to average amplitude and ... estimates a* and m* are of the amplitudes and positions of the binding sites, and the estimate N* is of the number of the components in the enriched regions.We solve the minimization problem for each ... thosethat yielded good performance. We chose a bandwidth of 30 for IP reads and a bandwidth of 300 for control reads. For enriched region i, we obtain four density functions,, , , , for the forward and reverse...
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Báo cáo y học: " A retrospective quality assessment of pre-hospital emergency medical documentation in motor vehicle accidents in south-eastern Norway"
... emergency vehi-cle with light -and- siren response for the study purposeonly.This study of documentation quality was part of across-sectional MVA study evaluating whether patientinjury pattern and ... analysis, and the drafting, revising, and final approval of the manuscript.SS was involved in the study conception and design, data analysis, and in the revising and final approval of the manuscript.Competing ... use in the study area, each template with a vari-ety of options for documenting patient physiology(Table 5). Given the variability in record template design and the fact that there was no formal...
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