... 19. Hayashi K, Ando N, Watanabe H, et al. Phase II evaluation of protracted infusion of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus: a Japan Esophageal Oncology ... Sakaeda T, Yamamori M, Kuwahara A, et al. Pharmacokinetics and pharmacogenomics in esophageal cancer chemoradio-therapy. Adv Drug Deliv Rev 2009; 61: 388-401. 11. Miki I, Tamura T, Nakamura ... of the most lethal [10]. Symptoms include dysphagia, odynophagia, and progressive weight loss. The two predominant histo-logical subtypes are adenocarcinoma and squamous cell carcinoma, and...