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Báo cáo y học: "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome" pot

Báo cáo y học:

Báo cáo y học: "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome" pot

... out NK cytotox-icity assays and manuscript preparation. EHG carried outstatistical analysis and manuscript preparation. TBG car-ried out patient referral, clinical data analysis and manu-script ... http:/ /arthritis- research.com/content/7/1/R30R30Vol 7 No 1Research articleNatural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage ... autoimmunedisease. Autoimmunity 2002, 35:1-14.29. Yabuhara A, Yang FC, Nakazawa T, Iwasaki Y, Mori T, Koike K,Kawa H, Komiyama A: A killing defect of natural killer cells as anunderlying immunologic abnormality...
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Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"

... fashion by the same investigator.Quantification of circulating Ang-1 and Ang-2Ang-1 and Ang-2 were measured by in-house Immuno Radio-metric Sandwich Assay (IRMA) and ELISA, respectively aspreviously ... illness (APACHE II and SOFA scores), pulmonary dysfunc-tion (PaO2/FiO2 and PaO2) and tissue hypoxia (lactate); usingmultivariate Cox proportional hazards regression analysis,Ang-2 was identified ... (R&D Systems,Minneapolis, USA). This assay measures biologically activeVEGF121 and VEGF165.Statistical analysisDifferences between patients and healthy controls were eval-uated using a non-parametric...
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Báo cáo y học:

Báo cáo y học: "Natural killer cells and autoimmunity" doc

... scores (DAS). Arthritis Rheum2002, 46(suppl 9):S490.33. Yabuhara A, Yang FC, Nakazawa T, Iwasaki Y, Mori T, Koike K,Kawai H, Komiyama A: A killing defect of natural killer cells asan underlying ... S, Yabe M, Muramatsu K, Kohdera U, Naka-date H, Kitazawa K, Toyoda Y, Ishii E: Low natural killer activity and central nervous system disease as a high-risk prognosticindicator in young patients ... natural killer cells and of gamma/delta T cells in systemic lupus erythematosus.Does it correlate to autoimmunity and to laboratory indices of disease activity? Lupus 2000, 9:333-337.43. Takahashi...
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Báo cáo y học: "Natural killer T cells and rheumatoid arthritis: friend or foe" ppt

... to healthy mice causes inflammatory arthritis by deposition of autoantibody in joint spaces,inducing an inflammatory cascade with activation of complement and Fcγ receptor pathways [14]. This ... encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001, 413(6855):531-534.12. Chiba A, Oki S, Miyamoto K, Hashimoto H, Yamamura T, MiyakeS: Suppression of collagen-induced arthritis ... arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide. Arthritis Rheum 2004, 50:305-313.13. Kim HY, Kim HJ, Min HS, Kim S, Park WS, Park...
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Báo cáo y học: "Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cell" ppsx

... three trials perday for four consecutive days, and the mean latency tofall of each day was considered for statistical analysis.Histological Examination and Immunohistochemistry:Purkinje CellsThree ... Venkataramana NK, Kumar SK, Balaraju S, Radhakrishnan RC, Bansal A, Dixit A, Rao DK, Das M, Jan M, Gupta PK, et al: Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal ... inheritedneurological disorders that are clin ically and geneticallyvery heterogeneous. They are progressive neurodegen-erative diseases that are characterised by cerebellarataxia, resulting in unstead y gait,...
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Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"

... Study (DWECS) and the national register on social transfer payments (DREAM). DREAM is a register based on data from the Danish Ministry of Employment, the Ministry of Social Affairs and the ... increase in absence days/yr. A 10-day increase in ab-sence days per annum (scale score ranging from 0-220 days/yr) yielded an increase in disability pension risk of approximately 35% (Cochran-Armitage ... analysis was performed in three stages: initially, analysis was performed to establish the association between days of sickness absence in 1990 and disability pension during follow-up. This...
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Báo cáo khoa học: Alpha 1-antichymotrypsin/SerpinA3 is a novel target of orphan nuclear receptor Nur77 potx

Báo cáo khoa học: Alpha 1-antichymotrypsin/SerpinA3 is a novel target of orphan nuclear receptor Nur77 potx

... pcDNA3.1-GST-Nur77plasmid. pSilencer-shNur77 was prepared by overlappingstrategy with primers 5¢-gacGGATCCgcagtccagccatgctcctttcaagagaaggagcatg-3¢ (with BamHI), 5¢-cggAAGCTTtATCGATccaaaaaacagtccagccatgctccttctcttg-3¢ ... 5¢-CACGCAGCTCATTGTAGAAGG-3¢. Another primer pairused for SerpinA3 was ACTas5-ACTas3: 5¢-GAATCCACCAGCTACATCCA-3¢ and 5¢-GTGCCCTCCTCAAATACATCA-3¢.Western blot assayThe cells were homogenized in lysis buffer ... 5¢-CTAATCTCTTCCTCCAAAAAGCACACAGA-3¢ for St-182 and St-93/-182, 5¢-AGAAATTATCATCTTTTCCAGTCCGAGA-3¢for St-93 and St-93/-182, and 5¢-TGGTCTTGAACTCCTCGTGATCTGCCCA-3¢ for Lst-595.pcDNA3.1-Nur77 expression plasmid...
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Báo cáo khoa học: Ets-1/ Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells pdf

Báo cáo khoa học: Ets-1/ Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells pdf

... critical mediator of dipeptidyl-peptidase IIItranscription in human glioblastoma cellsAbhay A. Shukla, Misti Jain and Shyam S. ChauhanDepartment of Biochemistry, All India Institute of Medical ... bovine and human cataractous lens[3], rabbit and human erythrocytes [4], rat brain [5] and pancreas [6], monkey brain [7], human placenta[8], neutrophils [9], Saccharomyces cerevisiae [10] and Drosophila ... amplifiedusing primers b-actin F (sense) (5¢-AGAAAATCTGGCACCACACC-3¢) and b-actin R (antisense) (5¢-TAG-CACAGCCTGGATAGCAA-3¢), and served as the inter-nal control. Melting-curve analysis was performed...
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Báo cáo khoa học: Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein potx

Báo cáo khoa học: Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein potx

... Takashi Baba, Tsuyoshi Fukushima and Hiroaki KataokaSection of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Japan Macrophage- stimulating ... chain of matureMSP (Fig. 1A) . Generation of a band of approxi-mately 30 kDa, presumably the b chain, was alsodetected by an anti-His tag IgG (Fig. 1A) . Cleavagesite analysis was performed after ... Hayashi T, Nishioka J, Nakagawa N, Kamada H,Gabazza EC, Kobayashi T, Hattori A & Suzuki K(2007) Proteinb C inhibitor directly and potentlyinhibits activated hepatocyte growth factor activator.J...
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Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf

Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf

... molecules, LAPP (anapproximately 13 kDa leech antiplatelet protein isola-ted from Haementeria of cinalis) and calin and sara-tin (approximately 65 kDa and 12 kDa proteins,respectively, both isolated ... hemato-phagy. The presence of anticoagulants in the salivaryglands of the leech, Hirudo medicinalis, was originallydiscovered by Haycraft in 1884 and led to the isola-tion of hirudin, a potent antithrombin ... platelet activation and release of secondarymediators (ADP and TxA2), which leads to plateletadhesion independently of a 2b1. However, in theabsence of the actions of secondary mediators,GPVI-mediated...
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