báo cáo khoa học: "Ultrasound-guided diagnostic breast biopsy methodology: retrospective comparison of the 8-gauge vacuum-assisted biopsy approach versus the spring-loaded 14-gauge core biopsy approach" pps

... for the 8-gauge vacuum-assisted biopsy group versus the spring-loaded 14-gauge core biopsy group. For neither the 8-gauge vacuum-assisted biopsy group nor the spring-loaded 14-gauge core biopsy ... AccessUltrasound-guided diagnostic breast biopsy methodology: retrospective comparison of the 8-gauge vacuum-assisted biopsy approach versus the spring-loaded 14-gauge core biopsy approach Stephen P Povoski1*, ... analysis for the number of cores removed at the time of the ultrasound-guided diagnostic breast biopsy was purely a reflection of the impact of the number of cores removed at the time of those 8-gauge...

Báo cáo khoa học: "Accelerated Partial Breast Irradiation (APBI): A review of available techniques" doc

... respect to the originaltumor site. The IORT approach has the advantage of shortening the treatment course further, conveniently delivering the ent ire course of local therapy at the time of initial ... cavity,distance from the surface of the balloon t o the skin sur-face, and the symmetry of the balloon in relationship to the central catheter. Treatment planning parameters are: the diameter of the inflated ... determine the effectiveness of the dosing.Target Definition The basic tenet of radiation therapy is the delivery of atumorcidal dose to the clinical target volume. In terms of applying APBI, there...

báo cáo khoa học: " Alcohol promotes breast cancer cell invasion by regulating the Nm23-ITGA5 pathway" ppt

... in the US [1]. Breast cancer is the second leading cause of cancer-related deaths amongwomen in the US, after lung cancer [2]. Often, it is not the primary tumor that leads to the death of cancerpatients ... placed in the upperchamber. The bottom chamber was filled with DMEMcontaining 10% FBS. The FBS attracted the cancer cellsand triggered their migration to the underside of the membrane. Breast ... Nm23 levels. The expression of integrins (e.g., ITGA5) in cancercells is essential as they allow the cells to attach to the endothelium found within the blood vessels of organssuch as the lungs...

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

... counter. Values are the mean of six replicates. The speciﬁc uptake was determined bysubtracting the uptake counts in the absence of inhibitorfrom the uptake counts in the presence of cocaine or S-cita-lopram, ... Co-expression of p25aand the dopamine transporter in HEK-293-MSR cells sensitized them to the toxicity of extracellular dopamine. Neuronal expression of p25a thusholds the potential to sensitize the ... of 200 lL of complete cell culture medium. After 48 h, the cells were incubated in the absence or presence of 0.5 mmDA. After 24 h of incubation at 37 °C, 5% CO2, the med-ium containing the...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

... present. This is because the con-struct used to determine the structure of the MLL1SET domain lacks the evolutionarily conserved Winmotif in the region ﬂanking the N-terminus of the SETdomain [26], ... observation). In the ternarycomplex, the histone H3 peptide binds in a deep chan-nel that divides a pair of acidic lobes, one of which iscomposed of residues from the SET-I region and the other of residues ... regulate the trimethyl form of histone H3? Does the regulation of H3K4 methylation involve posttranslational modiﬁ-cations in MLL1 or other proteins that regulate the assembly of the MLL1 core complex?...

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

... in all of these conditions [22]. In the trau-matically injured brain, however, the synthesis of MT1and MT2, as well as the synthesis of GIF, are up-regu-lated by reactive astrocytes in the vicinity ... lossin the AD brain. Further investigation of the increasedneurotrophic activity of the AD brain revealed that itcorrelated with the loss of a speciﬁc neuroinhibitoryfactor, rather than the presence ... ﬁneprocesses of these cells. Astrocytic synthesis of GIFis mainly found in the cortex, brainstem and spinalcord [6].Additionally however, there are also consistentreports of neuronal synthesis of GIF,...

Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx

... modules. The pathways for the individual carbohydrates, including the description of protein synthesis, are connected to the glycolysismodule. The PTS reactions, the synthesis of cAMPand the activation ... popular [21]. One advantage of the method of modular modeling is that the granularity of the submodels can easily be adjusted to the objective of the model and to the level of biological knowledgethat ... and synthesis of the PTS mRNA; brake actua-tor: describes the control and synthesis of the PtsGrepressor Mlc. Protein synthesis is described by takinginto account transcription (mRNAs of the...

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the PIR ⁄ BPS domain of Grb14,Depetris et al. [8] have ... we cannot assess whether the kinase activity of the IRs before KCl treatment repre-sents residual activity of receptors with Grb14 bound tothem, the activity of a fraction of receptors lackingbound ... interaction of Grb14 with the IR is probably the major determi-nant of the insulin-induced membrane translocation of Grb14, several lines of evidence suggest that the associ-ation of Grb14 via...

Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf

... described in the Materials and methods. Completion of the hydrolysis wasconﬁrmed by the disappearance of the (Met1)-ONC(M23L) signal in the MALDI-TOF mass spectra 1 h after the addition of AAP. The ... calculating the slope of the curves of Pyr-ONC (M23L) vs. time. From the rates of cyclizationshowninTable1,itcanbeinferredthattheformation of the N-terminal pyroglutamyl is not dependenton pH in the ... hydrogen bonded to the e-amino group of the Lys9 side-chain, which simultaneouslyinteracts with the main phosphate of the substrate [32]. The closer positioning of the N-terminus to the mainprotein...

Báo cáo khoa học: Physicochemical properties and distinct DNA binding capacity of the repressor of temperate Staphylococcus aureus phage /11 doc

... regu-late the transcription of genes located on the two sides of the /11 cI-cro intergenic region. Furthermore, the information gathered in the present study may proveuseful in the construction of ... homol-ogy over the entire length of the k repressor. Interest-ingly, although the sequences of the C-terminal ends of the above S. aureus phage repressors are identical, the sequences of their N-terminal ... majorgroove of the DNA helix [1]. Therefore, the data alsosuggest that the interaction between CI and the opera-tor DNA may occur through the major groove of the operator DNA helix. The absence of detectable...

Xem thêm