Báo cáo y học: "Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology" ppt
Báo cáo y học: "Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology" ppt
... Research and Therapy Vol 5 No 1 Roberts et al.Research articleAutologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histologySally Roberts1,2, ... staining for types I and IIIcollagens, patchy staining for type II collagen, and a little for type VI collagen. Most glycosaminoglycan staining was for chondroitin-4-sulfate, with less for keratan ... scheme used for the MR changes in thisstudy is at best only semiquantitative and may oversimplify and lose information that could be obtained by moresophisticated analysis. Fifty percent of...
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Báo cáo y học: "Detection of bone erosions in rheumatoid arthritis wrist joints with magnetic resonance imaging, computed tomography and radiography" ppt
... number not for citation purposes)The even higher agreement (87% vs 77%) between CT and MRI in a study of nine RA wrist joints by Perry and colleagues[12] may partly be explained by more advanced ... anatomy and presence of erosions difficult, and nutri-tive foramina may also resemble erosions [28]. This may, atleast partly, explain the lower sensitivity and accuracy in thiswrist joint study ... for detecting and monitoring bone erosions in RA. Thesensitivity to change is not yet established, however, and CTis disfavored by using ionising radiation and by the inability tovisualise...
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Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... study was to validate the model by means of the acquisition of new records for an additional analysis. Design: Non-paired case control study. Setting: Urban and rural hospitals and primary health ... analysis and bootstrap. Berkson’s bias was statistically assessed. Conclusions: The model, validated by means of logistic regression and bootstrap analysis, contains the variables AGE, TC, and ... colon in Dukes’ stages I and IIA by means of validation of a previous original model [18]. The model, validated by means of logistic regression and “bootstrap” analysis, contains the variables...
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Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... caldovelox and rat liver arginases alsoFig. 2. Effect of added Mn2+ and EDTA on the catalytic activity ofwild-type and D153N agmatinase. The enzymes were assayed before(Control) and after dialysis ... from decarboxylation of arginine by arginine decarboxylase [2], is a metabolic intermediate inthe biosynthesis of putrescine and higher polyamines [1] and may have important regulatory roles in ... catalysis by these enzymes, whichapparently evolved from a single primordial protein [6,7]. Inthis context, both enzymes exhibit an absolute requirement for Mn2+ for catalytic activity [8,9];...
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Báo cáo y học: "Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes" ppt
... positive for anti-Jo-1 by IPP were positive by LIA in all instances and by ALBIA in 14 (93.3%) cases. Sim-ilarly, sera with anti-U1RNP detected by IPP were also positive by ALBIA, and sera with ... with anti-fibrillarin by ALBIA were also pos-itive by TNT assay. Anti-PL-12 autoantibodies were detected by both IPP and LIA. However, a discrepancy in sensitivity wasnoted for anti-Ku, which ... extracted and purified from calf thymus (Immuno-vision. Springdale, AR, USA) [34]. For sera positive for anti-Ro by ALBIA, the specificity for anti-Ro52 and anti-Ro60 was fur-ther determined by ELISA...
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Báo cáo y học: "TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood" ppt
... dataanalysis. Study design was by LX, QZ, EMS, and BFB. LX, QZ, and RG were responsible for acquisition of data. Analysis and interpretation of data were performed by LX, QZ, RG, EMS, and BFB. ... haematopoiesis and incerebellar development. Nature 1998, 393:595-599.11. Yu X, Huang Y, Collin-Osdoby P, Osdoby P: Stromal cell-derivedfactor-1 (SDF-1) recruits osteoclast precursors by inducingchemotaxis, ... BFB, and QZ prepared the manuscript.Statistical analysis was performed by QZ and RG.AcknowledgementsThe murine TNF used in this study was provided by Amgen Inc. The authors thank Dr YR Zou...
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Báo cáo y học: " Effects of ischemic preconditioning on ischemia/ reperfusion-induced arrhythmias by upregulatation of connexin 43 expression" ppt
... electrophysiology of hypertrophied myocardium by up-regulating the expression of Cx43.Keywords: Cardioelectrial activity Connexin43, Ischemic preconditioning, Myocardial hypertrophyBackgroundVarious ... myocardial injury are present in hyper-trophic hearts of patients undergoing open heart surgery.The hypertrophied myocardium differs from normal myo-cardium in myocyte architecture and myocardial ... hearts.MethodsPreparation of animal models of myocardial hypertrophyHealthy New-Zealand rabbits weighing 2.3 ± 0.3 kg wereprov ided by the Laboratory Animals Center of Sun Yat-Sen University with the approval of...
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Báo cáo khoa học: Aptamers toEscherichia colicore RNA polymerase that sense its interaction with rifampicin, r-subunit and GreB ppt
... various ligands and regulatory factors and for investi-gating the conformational flexibility of the enz yme.Keywords: aptamers; conformational changes; elongationcomplex; Gr eB; R NA polymerase.DNA-directed ... r70-subunit and transcript cleavage factor GreB. Theresults indicate that stimulation of the R NAP endonucleaseactivity by GreB may be a ccompanied by significantconformational changes of the e nzyme. ... polymerase structure (Eur. J. Biochem. 271) 4925Aptamers toEscherichia colicore RNA polymerase that sense its interaction with rifampicin, r-subunit and GreBAndrey Kulbachinskiy1,2, Andrey...
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Báo cáo y học: "Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four-year clinical results" pdf
... culture-expanded chondrocytes in fibrin and polymer-based scaffolds made of polyglycolic acid or copolymers ofpolyglycolic and polylactic acid initiates chondrocyte re-differ-entiation in vitro and ... treatingconsecutive cartilage defects with BioSeed®-C, the study isFigure 7 Magnetic resonance imaging (MRI) before and four years after implan-tation of BioSeed®-CMagnetic resonance imaging (MRI) before and ... and used for autologous chondrocyte growth. Twenty millionchondrocytes were rearranged in fibrin and a polymer-basedscaffold (2 × 3 cm and 0.2 cm in height) of polyglycolic/poly-lactic acid (polyglactin,...
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Báo cáo y học: "Intensified thermal management for patients undergoing transcatheter aortic valve implantation (TAVI)" pdf
... cardiopulmonary bypass(CPB) is currently the treatment of choice for sympto-matic aortic stenosis but carries a significant risk of mor-bidity and mortality, particularly in frail elderly patientswith ... hypothermiacaused by general anesthesia and surgery. J Clin Anesth 2003, 15:119-125.20. Chassot PG, van der Linden P, Zaugg M, Mueller XM, Spahn DR: Off-pumpcoronary artery bypass surgery: ... management during off-pumpcoronary artery bypass graft surgery: a randomized clinical trial on theefficacy of a circulating water system versus a forced-air system. JCardiothorac Vasc Anesth...
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